ID X6M3K0_RETFI Unreviewed; 1368 AA.
AC X6M3K0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|Pfam:PF05729};
GN ORFNames=RFI_29183 {ECO:0000313|EMBL:ETO08206.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO08206.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO08206.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO08206.1}.
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DR EMBL; ASPP01025261; ETO08206.1; -; Genomic_DNA.
DR EnsemblProtists; ETO08206; ETO08206; RFI_29183.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 2.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR001646; 5peptide_repeat.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF00805; Pentapeptide; 1.
DR Pfam; PF00400; WD40; 9.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 7.
DR PROSITE; PS50082; WD_REPEATS_2; 10.
DR PROSITE; PS50294; WD_REPEATS_REGION; 9.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 484..645
FT /note="NACHT"
FT /evidence="ECO:0000259|Pfam:PF05729"
FT REPEAT 937..978
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 979..1020
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1021..1062
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1063..1104
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1105..1146
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1147..1188
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1200..1241
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1242..1283
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1284..1325
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1326..1367
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 463..490
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1368 AA; 156766 MW; FAC9E72203FEA9FF CRC64;
MTKLEKNEID NDHDSKLDEV RSNVKKEKEK AGVGEIKLGI NLQGSCTNAD CLAAKATLPV
WINHGFVEMS LDPEKSLHFA CPDCRKETVD SITKIVIYNA EHSIHASGDT QPVHDNHYQC
SYTIKPGLSY KVKASKIRQH ATSLEDLRER SEQAMNSVEI TNLIVKLEKY EITVVKPPKL
KGNDRLLEKI RSDYSGDFNQ AFDIGRFTIL CDNPTKLQTA VVVMKNAEEF NLIVSEDKDF
FDKQSKTHHR FHNIKLYVPK HDVYIEMQAT LKNFTTLEGY TVIENPKLSH LFYELIRAWK
PDNSSREEEL KQASDKTLTK INDVICEWIN ESEIKKIANR YKPHSDIGIL KPPQLNNKSE
LKDIDTDVPL KLAQFLYNQL CTFSPTKLKG KAIYVILFEY YKKHIVSEKH LATCFEVAST
LQESRKQELE EDVAILQALS TYTPLQANNY FYTDNDDQPD HGFDCYQHVI EFLEEKKDEQ
QRQVMILQGN SGSGKSLFCR YLEEHLWSNY INGLTKSIPV YISLPKCYKK EYESDVIAHA
LQVKHISKEM IEVIREQMSF ILIMDGFDEI FDAYSKTDCN EKFFYNRFHL NKWHAKVILT
CRSHVLNENN TKSTLIGSNS NNATAMIYLW PFSSQQMHGY IEKFVKLRKN NANNDNWTVE
QYEETLKKAQ VYEAFNEQWF DHHIQNISTK LAELRIQTNI RKMKLSLQSY CQDLGFDMFL
HGNQVATENN LEDEYKTESL RTKDIWEKYF NGDSVAKYVL RKVGENQYTF LHKSCQEYFA
AHKIICDILS WKQPTFDDDH KQFETQIQQQ SINCKLLNEE NGIIQFIVER LREKDSAFDN
LEYKLFQIIE ASKNLNTINI AAANAVTVLN SARINIHHKD WSNIKIPYAI LDNAFLEGTN
FANANLSNIS LAQAFLNETN FQNADMTGIY FGEHPNLEGH SGNVTSAYFS PDGQTVVSCS
WDKTIRLWDA DSGQELQIWK GHSDTVTEAQ FSPDGNTIVS SSWDKTIRLW DVKSGQELQK
WKGHSNYVSG VQFSSNGLTI LSCSFDKTIR IWEVASGKEI QKFQGHSESV RAAQFSPDCN
TIVSCSNDKS IRIWNVASGR ELQKLVGHSA NVLDVQFSPN GCFIVSASED QTVRIWDIMS
GQQLQKLEGH SEGVTAVQFS PDGRNIISSS LDKTIRLWEA LSGREIRKFE GHSNGFRGHV
DGHSNWVGGV QFSPDGNTVI SWSFDKTIRM WDAKTGRAIH KFDGHSRCVS QAQFFPNGHT
IVSCSYDNTI RLWDVDSGRE IQKLDLHSAP VGVVEFSPNG ETLLSCSYDQ TLRLWDTTSG
QLVPKIERHS KIISGAHFSP DGLTILLWFE DQVVRIWDAT LEREIQKI
//
