GenomeNet

Database: UniProt
Entry: X6MD79_RETFI
LinkDB: X6MD79_RETFI
Original site: X6MD79_RETFI 
ID   X6MD79_RETFI            Unreviewed;       501 AA.
AC   X6MD79;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   15-FEB-2017, entry version 10.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=RFI_25411 {ECO:0000313|EMBL:ETO11968.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Rhizaria; Foraminifera; Monothalamids; Reticulomyxidae;
OC   Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO11968.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO11968.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ETO11968.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; ASPP01021859; ETO11968.1; -; Genomic_DNA.
DR   EnsemblProtists; ETO11968; ETO11968; RFI_25411.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000023152};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM     53     71       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    106    125       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    184    205       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    217    236       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    243    263       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    283    302       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    435    460       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   501 AA;  56758 MW;  6FC283EDCF092C84 CRC64;
     MVRDKGKGTD SRYNETNNCP FKGSPSTYFE ENELIAAFQA IVDTYGMPRY KEFNPVIPTV
     ITFPFLFGVM YGDMFHGSCL LLFALCLLLA GKLTDLSQSD LSSLYSARYV LLLMGVFALY
     CGVIYNDCMS VMVNGWNGSQ WQHGYTTDDQ VVMVQRNVYA VGIDPAWSGV DNQLSFANSL
     KMKLAVIIGV IQMTFGLFLK LSNHIQENDF VSVWFEFIPQ MVFMMCFFGY MVFLIFYKWC
     INWASSTLSD MPSIITILIK MFLSPGSVDS EVQIFGDKNL QVIIQVTFLL ALVLSIPIML
     CVKPCILRSR MANHNYQNIP DDEKEETEVQ LPVVQSKEGE KAQKSQTIDE ESKQTEHEDS
     KDTDSHHSTQ HGQGHEHESF GDIMIHQLIH TIEYVLGTIS NTASYLRLWA LSLAHAELSE
     VFFDKTLRMT LESTGVGAVI MNVASAAAFL SFTCTVLLIM DVLECFLHAL RLHWVEFQSK
     FFYADGKAFR PFAFEKLLKA E
//
DBGET integrated database retrieval system