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Database: UniProt
Entry: X6N126_RETFI
LinkDB: X6N126_RETFI
Original site: X6N126_RETFI 
ID   X6N126_RETFI            Unreviewed;       469 AA.
AC   X6N126;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   15-FEB-2017, entry version 10.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
DE   Flags: Fragment;
GN   ORFNames=RFI_17612 {ECO:0000313|EMBL:ETO19618.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Rhizaria; Foraminifera; Monothalamids; Reticulomyxidae;
OC   Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO19618.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO19618.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ETO19618.1}.
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DR   EMBL; ASPP01013474; ETO19618.1; -; Genomic_DNA.
DR   EnsemblProtists; ETO19618; ETO19618; RFI_17612.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000023152};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    446    468       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:ETO19618.1}.
FT   NON_TER     469    469       {ECO:0000313|EMBL:ETO19618.1}.
SQ   SEQUENCE   469 AA;  53634 MW;  23BB99FDFED3E1F8 CRC64;
     RDVSKSFQEL SSQRSADIDL KRQWTERKSL FVLACHNPGN SFYEQAKVAV LRKLSAVLSE
     QSESAKQKLV GKYLLFVLER DKRGGEEGLK RVKGWNEIKT IMISYSDKKE DEGVSFSYIA
     GVVTRAQRVS LERQVYLTSR GNSWIRFEEA AATTTTTTTT KTLTVFVVFF LGSELHRSLR
     RLCQFMGISI CFECGAGEVM GATQSQEQLL EQTMKECEED KRAYVATHKL LKHVMRGIVK
     DLKQWKLTLL QERGICVIMN QFQSHSVHSV LRCEGWCPSY QKDHIQHILE QVVRDKGVGH
     AILTELILPN NNNNNNNNNN NNNNNNNKKQ LHTHKSHIRQ SPKTIVKQEG TNNAPIPLQT
     INREHHLLPT NDDDNDNDND NDDDTDNEEE MDFAHAQMIS LSQLQPPTHF EDNAFMTAFQ
     QIVDTYGVPR YKEFNPAVPT VITFPFLFGV MYGDIFHGMC LLLFSLALF
//
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