ID X6N7C8_RETFI Unreviewed; 888 AA.
AC X6N7C8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=RFI_15286 {ECO:0000313|EMBL:ETO21916.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO21916.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO21916.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO21916.1}.
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DR EMBL; ASPP01011191; ETO21916.1; -; Genomic_DNA.
DR AlphaFoldDB; X6N7C8; -.
DR EnsemblProtists; ETO21916; ETO21916; RFI_15286.
DR OrthoDB; 1095660at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51808; CHCH; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ETO21916.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT DOMAIN 192..368
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 382..568
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 649..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 101435 MW; D18A6D76A5EE1B0D CRC64;
MANTALPGRV QVVPPIKGVF PLDHFKECKR AEFAYLHCVK KHNGETYHCS SLIKDFLNCR
MDRSLMKRED LKQLGIPDTP EQTKNQFFFQ FKIKFVPILC NFGLLLKKII KFLNLGSINY
YYSNFLFIFK NATDFIFENL EQLWKVFFVF DLKGKIKMAG REKGLIQRIK NKTIKKMAQD
LLPVSRHEKE IIRTVAKNQV VLIVGATGSG KTTQVPQFML ELKREQVGKS TQVICTQPRQ
VAATSVAERV AKEMNCSLGS TVGYQIRFER KASDNTELMY VTEGILVRWI LSPEHANFKG
FSIVIVDEAH ERTVNTDILM ALLKKRIQMS KDSNNKDMPF FRAVIMSATM DKNRFQSYFP
GNPDVVDIPG RVYPVARNFL SEPVQDYVKT AAEIAYGIHS SLGNESGDIL IFLTGSQEID
DCIRHIDDLK RGSQSPRELL AIKFHSHIAN AKQDVFRKAL SSQRKCVVAT NIAETSLTID
GIVYVIDCGM SKQKLYDEAK HVDALEIRPI SKASVKQRVG RAGRTKPGMS FHLYPLKNYE
MLENENQPEI LRVSMIYETL CMLALGIENP LEFDYIDPPS ETTVARAVNM LFHLKAIDDK
GKLTKEGKHL TDFPLDPRLS KALLAASKYG VVNEVLSIAA MLEIHEKLSG RSDSKDNNSD
DDDNNGDDDN DNDGNGYGRR YKKGPSQNRP KNPMKIYKHC DGDHLTLLNI FNAYKHKHFQ
ESGYYRDPNV GHLERADKIR GRLEFALLRI LPEIKTSDQC DYKSRHYYPN ILKALLSGYF
LNVATYGYAD KYWTFRLASL NDKHKVVEFL DRAKPHRSSV FGGNKVQRRP WVFFHEVVVQ
QTVFLRILSA IQPKWLLEVA PDYFNVEQLA RDKSSVASIL RDLRNASS
//
