ID X6NS35_RETFI Unreviewed; 468 AA.
AC X6NS35;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=RFI_08602 {ECO:0000313|EMBL:ETO28529.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO28529.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO28529.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO28529.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ASPP01006616; ETO28529.1; -; Genomic_DNA.
DR AlphaFoldDB; X6NS35; -.
DR EnsemblProtists; ETO28529; ETO28529; RFI_08602.
DR OrthoDB; 51135at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF151; TNF RECEPTOR ASSOCIATED FACTOR (TRAF) HOMOLOG; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF02176; zf-TRAF; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50145; ZF_TRAF; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 98..143
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 175..223
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 402..468
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT ZN_FING 98..143
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 175..223
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT COILED 242..269
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 303..337
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 468 AA; 54579 MW; 3C1836B6873A5E91 CRC64;
MSNSIVDTNI KEESIDCPAN IIVKSKCVAF EKYRLLDGVL QGSNGKTLSC VQDESKRKKN
KRYLKAHTEL QKEINVNVIV KCAKCKSGEM NLKDYKLHVS ERCPKTLVLC PFCSTQVFRK
HLNKHKKSCP MATVDCPLAC DKEGGERKIK KNGVDQRKDF GEDFFFLKRV FESHHVKTEC
ENALLICPNV SCKKRVLRRD MANHLAVECY YRLVDCPFAK HGCSQKSLIP SEMKRHEDSN
LLHHLKLRMD HLEEKNDETV SRLHQEQEAF EQKFEKRLLR LERQNYRMKR KYRTIIRTLK
GSKAELQRKE TLLLDEKQQL EEKCSEWRSL YGQLKCQSNM NRMSLVSDDT SLSENTRSEL
MSSKHRELQN TVENNSDDSE IVIFDVSDQE GLDKEEIMNQ CKVVKQGNLL KQGNKFHTWR
KRFFVLMDDG CLYYYDMAKK TSNPLGQINT FEVTEAKAIH VSPKRPYG
//
