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Database: UniProt
Entry: X7F2X8_9RHOB
LinkDB: X7F2X8_9RHOB
Original site: X7F2X8_9RHOB 
ID   X7F2X8_9RHOB            Unreviewed;       338 AA.
AC   X7F2X8;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   RecName: Full=Exodeoxyribonuclease 7 large subunit {ECO:0000256|SAAS:SAAS00723543};
DE            EC=3.1.11.6 {ECO:0000256|SAAS:SAAS00723538};
DE   Flags: Fragment;
GN   ORFNames=RISW2_16350 {ECO:0000313|EMBL:ETX27145.1};
OS   Roseivivax isoporae LMG 25204.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Roseivivax.
OX   NCBI_TaxID=1449351 {ECO:0000313|EMBL:ETX27145.1, ECO:0000313|Proteomes:UP000023430};
RN   [1] {ECO:0000313|EMBL:ETX27145.1, ECO:0000313|Proteomes:UP000023430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 25204 {ECO:0000313|EMBL:ETX27145.1,
RC   ECO:0000313|Proteomes:UP000023430};
RA   Lai Q., Li G., Shao Z.;
RT   "Roseivivax isoporae LMG 25204 Genome Sequencing.";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Bidirectionally degrades single-stranded DNA into large
CC       acid-insoluble oligonucleotides, which are then degraded further
CC       into small acid-soluble oligonucleotides.
CC       {ECO:0000256|SAAS:SAAS00723532}.
CC   -!- CATALYTIC ACTIVITY: Exonucleolytic cleavage in either 5'- to
CC       3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.
CC       {ECO:0000256|SAAS:SAAS00723505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00723552}.
CC   -!- SIMILARITY: Belongs to the XseA family.
CC       {ECO:0000256|SAAS:SAAS00723548}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ETX27145.1}.
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DR   EMBL; JAME01000040; ETX27145.1; -; Genomic_DNA.
DR   RefSeq; WP_043774190.1; NZ_JAME01000040.1.
DR   EnsemblBacteria; ETX27145; ETX27145; RISW2_16350.
DR   Proteomes; UP000023430; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR   GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR   CDD; cd04489; ExoVII_LU_OBF; 1.
DR   HAMAP; MF_00378; Exonuc_7_L; 1.
DR   InterPro; IPR003753; Exonuc_VII_L.
DR   InterPro; IPR020579; Exonuc_VII_lsu_C.
DR   InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR   PANTHER; PTHR30008; PTHR30008; 1.
DR   Pfam; PF02601; Exonuc_VII_L; 1.
DR   Pfam; PF13742; tRNA_anti_2; 1.
DR   TIGRFAMs; TIGR00237; xseA; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000023430};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00723549};
KW   Exonuclease {ECO:0000256|SAAS:SAAS00723511};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00723558};
KW   Nuclease {ECO:0000256|SAAS:SAAS00723518};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023430}.
FT   DOMAIN       15    108       tRNA_anti_2. {ECO:0000259|Pfam:PF13742}.
FT   DOMAIN      131    336       Exonuc_VII_L. {ECO:0000259|Pfam:PF02601}.
FT   NON_TER     338    338       {ECO:0000313|EMBL:ETX27145.1}.
SQ   SEQUENCE   338 AA;  36578 MW;  BDE4D56C4D6BFE4C CRC64;
     MDLIEDEDSG NTPEFTVSEI SGAVKRTIEG AFGHVRIRGE VGRVSRPRSG HVYLDLKDDR
     AVISGVVWKG TAVRLDTQPE EGLEVVATGR LTTFPGQSKY QMVIEDIRPA GQGALMAMLE
     KRRTALAAEG LFDEARKRPL PFLPEVIGVV TSPSGAVIRD ILHRLRERFP RKVLIWPVAV
     QGAACAPEVA RAIAGFNALT PGGALPRPDL LIVARGGGSI EDLWGFNEEA VVRAAAASDI
     PLISAVGHET DTTLIDFAAD RRAPTPTAAA EIAVPVRRDL LAWTGEMQAR LGRAVADRLD
     RRAERLRDLS RALPRPDALL DPARQRLDIA SERLPAAL
//
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