ID Y5095_DICDI Reviewed; 263 AA.
AC Q54NS3;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=TPR repeat-containing protein DDB_G0285095;
GN ORFNames=DDB_G0285095;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000073; EAL65011.1; -; Genomic_DNA.
DR RefSeq; XP_639994.1; XM_634902.1.
DR AlphaFoldDB; Q54NS3; -.
DR SMR; Q54NS3; -.
DR STRING; 44689.Q54NS3; -.
DR PaxDb; 44689-DDB0231412; -.
DR EnsemblProtists; EAL65011; EAL65011; DDB_G0285095.
DR GeneID; 8624912; -.
DR KEGG; ddi:DDB_G0285095; -.
DR dictyBase; DDB_G0285095; -.
DR eggNOG; KOG4132; Eukaryota.
DR HOGENOM; CLU_1059332_0_0_1; -.
DR InParanoid; Q54NS3; -.
DR OMA; FAINCEK; -.
DR Reactome; R-DDI-6804760; Regulation of TP53 Activity through Methylation.
DR PRO; PR:Q54NS3; -.
DR Proteomes; UP000002195; Chromosome 4.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR26312; TETRATRICOPEPTIDE REPEAT PROTEIN 5; 1.
DR PANTHER; PTHR26312:SF87; TETRATRICOPEPTIDE REPEAT PROTEIN 5; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..263
FT /note="TPR repeat-containing protein DDB_G0285095"
FT /id="PRO_0000389242"
FT REPEAT 87..120
FT /note="TPR 1"
FT REPEAT 121..154
FT /note="TPR 2"
FT REPEAT 162..195
FT /note="TPR 3"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 263 AA; 29748 MW; 9EA400BAEDC53F84 CRC64;
MGCCGSKEKY NGEDVPKSQR LENRPTNDVN GKQPQRQQPP NKRKNNTIRK GAASASQQNN
PTSLFEITDL SLKNDIIEGL QEQPQDSDLL AQYGVLLSME GKNKEAEESL RKAVEVDTDN
SRAWQAYGEF LERTNNPKKA KEVYGEAYKH AAPKIALDED DSSLLLSYAI FIQKSGEIDK
AEKLYKRIVT SGARSSESLG RYGLFLLEVK KDVEKGGIYL KDAADIDPPS PEWCTRYSNY
LKTYKKDEFE ATKYQKRVSL YVN
//
