ID   Y595_COREF              Reviewed;         530 AA.
AC   Q8FS11;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   RecName: Full=Uncharacterized transporter CE0595;
GN   OrderedLocusNames=CE0595;
OS   Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS   / NBRC 100395).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=196164;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX   PubMed=12840036; DOI=10.1101/gr.1285603;
RA   Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA   Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT   "Comparative complete genome sequence analysis of the amino acid
RT   replacements responsible for the thermostability of Corynebacterium
RT   efficiens.";
RL   Genome Res. 13:1572-1579(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; BA000035; BAC17405.1; -; Genomic_DNA.
DR   RefSeq; WP_006769728.1; NZ_GG700687.1.
DR   AlphaFoldDB; Q8FS11; -.
DR   STRING; 196164.gene:10740997; -.
DR   KEGG; cef:CE0595; -.
DR   eggNOG; COG0569; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_0_11; -.
DR   OrthoDB; 9155749at2; -.
DR   Proteomes; UP000001409; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR018225; Transaldolase_AS.
DR   InterPro; IPR006512; YidE_YbjL.
DR   NCBIfam; TIGR01625; YidE_YbjL_dupl; 2.
DR   PANTHER; PTHR30445:SF3; TRANSPORT PROTEIN YIDE-RELATED; 1.
DR   PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR   PROSITE; PS51202; RCK_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..530
FT                   /note="Uncharacterized transporter CE0595"
FT                   /id="PRO_0000208768"
FT   TRANSMEM        4..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        352..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        379..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        419..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        451..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          260..344
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   530 AA;  55367 MW;  DE3D333CC304CA1F CRC64;
     MLDFLAANPL IALAVILAVG LAIGRISLFG VSLGAAAVLI VALVVSTLNP DIQIPAFVFQ
     LGLAMFVYVI GISAGPAFFR EFRSRGWKLT LFMITLLVSL TALAWVLIRA FGLGAGAGAG
     MFAGSLTSTP GMAAVVALMD PAQAGDPVIG YSLAYPGAVL GSILVAAVGA KLLKVNHTED
     AREEGLVTEP LVWKGVRIGE GISGTIGDLP RLSGQQIIAT RIVEDPHEHR LADPTLPIKP
     GMELVINGTV NAVDRAIAAL GGECDTKIED TELVYSRFTV SNPDIVGRTV AELDPVANGF
     MIARIRQGDT EIVPHRDTVL NYSDRVRVVA APGRMGEVRR FLGDSEKALG DVNLLPFAIG
     LSLGLLLGAI PVPLPGDTTM YLGFGGGPIV AGLILGALNR TGPITWQLPF HANRTISTLG
     LALFLAGVGT SAGAGFRQAL TDPQSFVYMG VGFAITVTSA LVCAVVGMWL LKLKWDESMG
     VAAGATTNPA IISYLNDQTG TDLANRGYAT VYPTAMIGKI LACQVLFLLL
//