ID YBAC_BACSU Reviewed; 318 AA.
AC P70981; Q797S3;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 27-MAR-2024, entry version 115.
DE RecName: Full=Probable aminopeptidase YbaC;
DE EC=3.4.11.-;
GN Name=ybaC; OrderedLocusNames=BSU01140;
OS Bacillus subtilis (strain 168).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8969501; DOI=10.1099/13500872-142-11-3039;
RA Yasumoto K., Liu H., Jeong S.M., Ohashi Y., Kakinuma S., Tanaka K.,
RA Kawamura F., Yoshikawa H., Takahashi H.;
RT "Sequence analysis of a 50 kb region between spo0H and rrnH on the Bacillus
RT subtilis chromosome.";
RL Microbiology 142:3039-3046(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO 316.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
CC -!- FUNCTION: Probable aminopeptidase. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peptidase S33 family. {ECO:0000305}.
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DR EMBL; D64127; BAA11005.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB11890.2; -; Genomic_DNA.
DR PIR; D69742; D69742.
DR RefSeq; NP_387995.2; NC_000964.3.
DR RefSeq; WP_003235060.1; NZ_JNCM01000029.1.
DR AlphaFoldDB; P70981; -.
DR SMR; P70981; -.
DR STRING; 224308.BSU01140; -.
DR ESTHER; bacsu-YBAC; Proline_iminopeptidase.
DR PaxDb; 224308-BSU01140; -.
DR EnsemblBacteria; CAB11890; CAB11890; BSU_01140.
DR GeneID; 936866; -.
DR KEGG; bsu:BSU01140; -.
DR PATRIC; fig|224308.179.peg.117; -.
DR eggNOG; COG0596; Bacteria.
DR InParanoid; P70981; -.
DR OrthoDB; 53505at2; -.
DR PhylomeDB; P70981; -.
DR BioCyc; BSUB:BSU01140-MONOMER; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR022742; Hydrolase_4.
DR InterPro; IPR002410; Peptidase_S33.
DR PANTHER; PTHR43689:SF53; ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43689; HYDROLASE; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PRINTS; PR00793; PROAMNOPTASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Aminopeptidase; Hydrolase; Protease; Reference proteome.
FT CHAIN 1..318
FT /note="Probable aminopeptidase YbaC"
FT /id="PRO_0000359934"
FT ACT_SITE 115
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 266
FT /evidence="ECO:0000250"
FT ACT_SITE 296
FT /note="Proton donor"
FT /evidence="ECO:0000250"
FT CONFLICT 316
FT /note="H -> N (in Ref. 1; BAA11005)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 318 AA; 36916 MW; 31A7250A58B6543A CRC64;
MIPEKKSIAI MKELSIGNTK QMLMINGVDV KNPLLLFLHG GPGTPQIGYV RHYQKELEQY
FTVVHWDQRG SGLSYSKRIS HHSMTINHFI KDTIQVTQWL LAHFSKSKLY LAGHSWGSIL
ALHVLQQRPD LFYTYYGISQ VVNPQDEEST AYQHIREISE SKKASILSFL TRFIGAPPWK
QDIQHLIYRF CVELTRGGFT HRHRQSLAVL FQMLTGNEYG VRNMHSFLNG LRFSKKHLTD
ELYRFNAFTS VPSIKVPCVF ISGKHDLIVP AEISKQYYQE LEAPEKRWFQ FENSAHTPHI
EEPSLFANTL SRHARHHL
//
