ID YTFE_SALTI Reviewed; 220 AA.
AC Q8Z157; Q7C534;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 24-JAN-2024, entry version 107.
DE RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN OrderedLocusNames=STY4757, t4452;
OS Salmonella typhi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR EMBL; AL513382; CAD06878.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO71899.1; -; Genomic_DNA.
DR RefSeq; NP_458835.1; NC_003198.1.
DR RefSeq; WP_000331469.1; NZ_WSUR01000012.1.
DR AlphaFoldDB; Q8Z157; -.
DR SMR; Q8Z157; -.
DR STRING; 220341.gene:17588578; -.
DR KEGG; stt:t4452; -.
DR KEGG; sty:STY4757; -.
DR PATRIC; fig|220341.7.peg.4859; -.
DR eggNOG; COG2846; Bacteria.
DR HOGENOM; CLU_076075_2_0_6; -.
DR OMA; ACTTWRV; -.
DR OrthoDB; 9797132at2; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.120.520; nmb1532 protein domain like; 1.
DR HAMAP; MF_01606; RIC_YtfE; 1.
DR InterPro; IPR023742; FeS-repair_YftE.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR019903; RIC_family.
DR NCBIfam; TIGR03652; FeS_repair_RIC; 1.
DR PANTHER; PTHR36438; IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE; 1.
DR PANTHER; PTHR36438:SF1; IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF04405; ScdA_N; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Iron; Metal-binding; Stress response.
FT CHAIN 1..220
FT /note="Iron-sulfur cluster repair protein YtfE"
FT /id="PRO_0000213054"
SQ SEQUENCE 220 AA; 24866 MW; 5FA4D10F088375F5 CRC64;
MAYRDQPLGE LALSIPRASA LFRQYDMDYC CGGKQTLARA AARHDVDIDI IEAQLAQLAE
QPIEKDWRAV PLADIIDHIV VRYHDRHREQ LPELILQATK VERVHADKPN VPRGLTKYLT
ALHEELSSHM MKEEQILFPM IKQGMGRQAT GPISVMESEH DEAGELVDVI KHVTQNVTPP
PEACTTWKAM YNGINEMIDA LMEHISLENN VLFPRALAGE
//
