GenomeNet

Database: UniProt
Entry: Z4YLZ2_MOUSE
LinkDB: Z4YLZ2_MOUSE
Original site: Z4YLZ2_MOUSE 
ID   Z4YLZ2_MOUSE            Unreviewed;       474 AA.
AC   Z4YLZ2;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   30-AUG-2017, entry version 25.
DE   SubName: Full=Transient receptor potential cation channel subfamily V member 1 {ECO:0000313|Ensembl:ENSMUSP00000116400};
DE   Flags: Fragment;
GN   Name=Trpv1 {ECO:0000313|Ensembl:ENSMUSP00000116400,
GN   ECO:0000313|MGI:MGI:1341787};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000116400, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000116400, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000116400,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000116400}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000116400};
RG   Ensembl;
RL   Submitted (APR-2014) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000116400}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AL663116; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PaxDb; Z4YLZ2; -.
DR   Ensembl; ENSMUST00000138853; ENSMUSP00000116400; ENSMUSG00000005952.
DR   MGI; MGI:1341787; Trpv1.
DR   eggNOG; KOG3676; Eukaryota.
DR   eggNOG; ENOG4110DG4; LUCA.
DR   GeneTree; ENSGT00550000074425; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   Bgee; ENSMUSG00000005952; -.
DR   ExpressionAtlas; Z4YLZ2; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043005; C:neuron projection; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0097603; F:temperature-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050960; P:detection of temperature stimulus involved in thermoception; IEA:Ensembl.
DR   GO; GO:0002024; P:diet induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0001660; P:fever generation; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0002790; P:peptide secretion; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0050954; P:sensory perception of mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0060083; P:smooth muscle contraction involved in micturition; IEA:Ensembl.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR024862; TRPV.
DR   InterPro; IPR008347; TRPV1-4_channel.
DR   InterPro; IPR024863; TRPV1_channel.
DR   PANTHER; PTHR10582; PTHR10582; 1.
DR   PANTHER; PTHR10582:SF38; PTHR10582:SF38; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01768; TRPVRECEPTOR.
DR   TIGRFAMs; TIGR00870; trp; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    126    145       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    165    183       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    204    224       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    230    249       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    270    292       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    350    374       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      128    386       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   NON_TER     474    474       {ECO:0000313|Ensembl:ENSMUSP00000116400}.
SQ   SEQUENCE   474 AA;  54797 MW;  0B7485269FCDD4A6 CRC64;
     MYNEILILGA KLHPTLKLEE LTNKKGLTPL ALAASSGKIG VLAYILQREI HEPECRHLSR
     KFTEWAYGPV HSSLYDLSCI DTCEKNSVLE VIAYSSSETP NRHDMLLVEP LNRLLQDKWD
     RFVKRIFYFN FFVYCLYMII FTTAAYYRPV EGLPPYKLNN TVGDYFRVTG EILSVSGGVY
     FFFRGIQYFL QRRPSLKSLF VDSYSEILFF VQSLFMLVSV VLYFSHRKEY VASMVFSLAM
     GWTNMLYYTR GFQQMGIYAV MIEKMILRDL CRFMFVYLVF LFGFSTAVVT LIEDGKNNSL
     PVESPPHKCR GSACRPGNSY NSLYSTCLEL FKFTIGMGDL EFTENYDFKA VFIILLLAYV
     ILTYILLLNM LIALMGETVN KIAQESKNIW KLQRAITILD TEKSFLKCMR KAFRSGKLLQ
     VGFTPDGKDD FRWCFRVDEV NWTTWNTNVG IINEDPGNCE GVKRTLSFSL RSGR
//
DBGET integrated database retrieval system