ID Z9JQN9_9MICO Unreviewed; 298 AA.
AC Z9JQN9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Dihydrodipicolinate synthase {ECO:0000313|EMBL:EWS80353.1};
GN ORFNames=BF93_04005 {ECO:0000313|EMBL:EWS80353.1};
OS Brachybacterium phenoliresistens.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=396014 {ECO:0000313|EMBL:EWS80353.1, ECO:0000313|Proteomes:UP000023067};
RN [1] {ECO:0000313|EMBL:EWS80353.1, ECO:0000313|Proteomes:UP000023067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W13A50 {ECO:0000313|EMBL:EWS80353.1,
RC ECO:0000313|Proteomes:UP000023067};
RA Wang X.;
RT "Genome sequence of Brachybacterium phenoliresistens strain W13A50.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWS80353.1}.
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DR EMBL; JDYK01000016; EWS80353.1; -; Genomic_DNA.
DR RefSeq; WP_038373503.1; NZ_KK069999.1.
DR AlphaFoldDB; Z9JQN9; -.
DR STRING; 396014.BF93_04005; -.
DR PATRIC; fig|396014.3.peg.2834; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_049343_5_0_11; -.
DR OrthoDB; 9778880at2; -.
DR Proteomes; UP000023067; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000023067}.
FT ACT_SITE 137
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 165
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 206
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 298 AA; 32436 MW; 13CEC7DAC82D4533 CRC64;
MTDRKPWHGI IVASSLPFRE DLEIDHEAYA ADVAWLAEQG CDGVAPNGSL GEYQSLSWQE
RDAVVATAID AAPEGFTVMP GVGAYSGRES LRHAQAARDL GAQAVMALPP NAYRADERAI
LEHFELIASA GLPVTAYNNP LDTKVDLTPR LLAKLHHEGL VVGVKEFSGD VRRCYELAEL
APGMDLIIGT DDSVLEVGLC GAKGWVAGFS QVFPQATRTL YEASVAGDVA TALPLYRELH
ALLRWDTKTE FVQAIKIGQE MIGRAPHARC RPPRQPLLPE QEAEVRSLVQ RHLDAGLR
//
