ID   O33938_SACER            Unreviewed;       322 AA.
AC   O33938;
DT   01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT   01-JAN-1998, sequence version 1.
DT   28-JUL-2009, entry version 30.
DE   SubName: Full=EryBIV;
DE   SubName: Full=Putative deoxyhexose reductase;
GN   Name=eryBIV; Synonyms=EryBIV;
OS   Saccharopolyspora erythraea (Streptomyces erythraeus).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Pseudonocardineae; Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=1836;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL 2338;
RX   MEDLINE=98015410; PubMed=9353926;
RA   Summers R.G., Donadio S., Staver M.J., Wendt-Pienkowski E.,
RA   Hutchinson C.R., Katz L.;
RT   "Sequencing and mutagenesis of genes from the erythromycin
RT   biosynthetic gene cluster of Saccharopolyspora erythraea that are
RT   involved in L-mycarose and D-desosamine production.";
RL   Microbiology 143:0-0(0).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL 2338;
RA   Summers R.G., Staver M.J., Donadio S., Wendt-Pienkowski E.,
RA   Hutchinson C.R., Katz L.;
RL   Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL2338;
RX   MEDLINE=98055166; PubMed=9393448; DOI=10.1007/s004380050566;
RA   Gaisser S., Bohm G.A., Cortes J., Leadlay P.F.;
RT   "Analysis of seven genes from the eryAI-eryK region of the
RT   erythromycin biosynthetic gene cluster in Saccharopolyspora
RT   erythraea.";
RL   Mol. Gen. Genet. 256:239-251(1997).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; U77459; AAB84071.1; -; Genomic_DNA.
DR   EMBL; Y11199; CAA72080.1; -; Genomic_DNA.
DR   RefSeq; YP_001102987.1; -.
DR   GeneID; 4940581; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; IEA:InterPro.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF01370; Epimerase; 1.
PE   4: Predicted;
SQ   SEQUENCE   322 AA;  34007 MW;  326C86A0E4BDFC19 CRC64;
     MNGISDSPRQ LITLLGASGF VGSAVLRELR DHPVRLRAVS RGGAPAVPPG AAEVEDLRAD
     LLEPGRAAAA IEDADVIVHL VAHAAGGSTW RSATSDPEAE RVNVGLMHDL VGALHDRRRS
     TPPVLLYAST AQAANPSAAS RYAQQKTEAE RILRKATDEG RVRGVILRLP AVYGQSGPSG
     PMGRGVVAAM IRRALAGEPL TMWHDGGVRR DLLHVEDVAT AFAAALEHHD ALAGGTWALG
     ADRSEPLGDI FRAVSGSVAR QTGSPAVDVV TVPAPEHAEA NDFRSDDIDS TEFRSRTGWR
     PRVSLTDGID RTVAALTPTE EH
//

ID   Q9XC69_STRFR            Unreviewed;       347 AA.
AC   Q9XC69;
DT   01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1999, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   SubName: Full=NDP-hexose 4-ketoreductase TylCIV;
GN   Name=tylCIV;
OS   Streptomyces fradiae.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1906;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=T59235;
RX   MEDLINE=20121747; PubMed=10658660;
RA   Bate N., Butler A.R., Smith I.P., Cundliffe E.;
RT   "The mycarose-biosynthetic genes of Streptomyces fradiae, producer of
RT   tylosin.";
RL   Microbiology 146:139-146(2000).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AF147704; AAD41822.1; -; Genomic_DNA.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; IEA:InterPro.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF01370; Epimerase; 1.
PE   4: Predicted;
SQ   SEQUENCE   347 AA;  36260 MW;  7A5AB5C5BF38DBB0 CRC64;
     MSMPLVPGPA RDGRRPLVVL LGASGFLGSA VAAELARRPV RLRLVARRPS PVPAGAVAEI
     EVRRRDLSLP GEVTEAVEDA DAVVHLVAHT GGEKSWRAAG ERSEHINVGL MRELAEALRP
     TGPADATRAP VVLFGSTLQA GMEQAHTPGT YAAQKLAAER VLHRADAEGA VRGVVLRLTT
     VIGRSPLTGS PGRGVIAVTA GRALAGDPIT MWHDGSVERD LLDVRDAATA FTTALEHADQ
     LRGKHWVVGT GRRHRLDRVF GTVAALAAEH TGRPPVPVVT VDPPGYAEVC DFRTPDSDPS
     AFRAVTGWRP RAEPADGIAA AIAAVAGAGD SPEPEGAGKR GGGTERR
//