ID   O52554_AMYMD            Unreviewed;       235 AA.
AC   O52554;
DT   01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 2.
DT   19-JAN-2010, entry version 29.
DE   SubName: Full=RifN;
GN   Name=rifN;
OS   Amycolatopsis mediterranei (Nocardia mediterranei).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Pseudonocardineae; Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=33910;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S699;
RX   MEDLINE=98174059; PubMed=9512878; DOI=10.1016/S1074-5521(98)90141-7;
RA   August P.R., Tang L., Yoon Y.J., Ning S., Muller R., Yu T.W.,
RA   Taylor M., Hoffmann D., Kim C.G., Zhang X., Hutchinson C.R.,
RA   Floss H.G.;
RT   "Biosynthesis of the ansamycin antibiotic rifamycin: deductions from
RT   the molecular analysis of the rif biosynthetic gene cluster of
RT   Amycolatopsis mediterranei S699.";
RL   Chem. Biol. 5:69-79(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S699;
RX   MEDLINE=98165773; PubMed=9497318; DOI=10.1074/jbc.273.11.6030;
RA   Kim C.G., Yu T.W., Fryhle C.B., Handa S., Floss H.G.;
RT   "3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the
RT   formation of the precursor of mC7N units in rifamycin and related
RT   antibiotics.";
RL   J. Biol. Chem. 273:6030-6040(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S699;
RX   MEDLINE=21201076; PubMed=11278540; DOI=10.1074/jbc.M009667200;
RA   Yu T.W., Muller R., Muller M., Zhang X., Draeger G., Kim C.G.,
RA   Leistner E., Floss H.G.;
RT   "Mutational analysis and reconstituted expression of the biosynthetic
RT   genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the
RT   starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei
RT   S699.";
RL   J. Biol. Chem. 276:12546-12555(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S699;
RA   Yu T.-W., Pogosova-Agadjanyan E.L., Kuan L.-Y., Bai L., Tin A.M.,
RA   Adman E., Floss H.G.;
RT   "Rifamycin insusceptibility: exploring the rif gene cluster of
RT   Amycolatopsis mediterranei S699.";
RL   Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S699;
RA   Yu T., August P.R., Tang L., Yoon Y.J., Ning S., Mueller R.,
RA   Taylor M., Kim C., Zhang X., Pogosova-Agadjanyan E.L., Tin A.M.,
RA   Hutchinson C.R., Floss H.G.;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AF040570; AAC01722.2; -; Genomic_DNA.
DR   SMR; O52554; 1-227.
DR   InterPro; IPR000600; ROK.
DR   Pfam; PF00480; ROK; 1.
PE   4: Predicted;
SQ   SEQUENCE   235 AA;  23689 MW;  018C56F6E2F30211 CRC64;
     MPGTVGADGR VATWPSRPEW TGVDLKTALH SLFPEAAVAW ADDGDLGALA ESRASGCENL
     LYIGIGTGIG GGLVLGGVPC PGLGRGSFEI GHVIVEMGGV RCVCGRRGCL QALASGPATL
     RRASLLRGAD VTYYRLQRAL RNGEPWAADA LEGSTRALAA AVTGVQELVH PDRVLIGGGF
     AAGIPEIVPS VSGFLADLVR QGQAPLPVEP AALGGLSSLR GAVALAGLVA AGEVP
//