ID   O69208_ACTPA            Unreviewed;       387 AA.
AC   O69208;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   19-JAN-2010, entry version 35.
DE   SubName: Full=Oxidoreductase;
OS   Actinosynnema pretiosum subsp. auranticum.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Pseudonocardineae; Actinosynnemataceae; Actinosynnema.
OX   NCBI_TaxID=42198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC31565;
RA   Kim C.G., Kirschning A., Bergon P., Ahn Y., Wang J.J., Shibuya M.,
RA   Floss H.G.;
RT   "Formation of 3-amino-5-hydroxy-benzoic acid, the precursor of mC7N
RT   units in ansamycin antibiotics, by a new variant of the shikimate
RT   pathway.";
RL   J. Am. Chem. Soc. 114:4941-4943(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC31565;
RX   MEDLINE=98174059; PubMed=9512878; DOI=10.1016/S1074-5521(98)90141-7;
RA   August P.R., Tang L., Yoon Y.J., Ning S., Muller R., Yu T.W.,
RA   Taylor M., Hoffmann D., Kim C.G., Zhang X., Hutchinson C.R.,
RA   Floss H.G.;
RT   "Biosynthesis of the ansamycin antibiotic rifamycin: deductions from
RT   the molecular analysis of the rif biosynthetic gene cluster of
RT   Amycolatopsis mediterranei S699.";
RL   Chem. Biol. 5:69-79(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC31565;
RX   MEDLINE=98165773; PubMed=9497318; DOI=10.1074/jbc.273.11.6030;
RA   Kim C.G., Yu T.W., Fryhle C.B., Handa S., Floss H.G.;
RT   "3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the
RT   formation of the precursor of mC7N units in rifamycin and related
RT   antibiotics.";
RL   J. Biol. Chem. 273:6030-6040(1998).
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DR   EMBL; U33059; AAC14003.1; -; Genomic_DNA.
DR   SMR; O69208; 11-340.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR000683; Oxidoreductase_N.
DR   InterPro; IPR004104; OxRdtase_C.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
PE   4: Predicted;
SQ   SEQUENCE   387 AA;  40105 MW;  50FA9628F882770D CRC64;
     MSAGSGGVRG GPVRVAVVGL GWVAREVWLP RLLGGAAYRV VAVVEPSARA RAAVLGDLTG
     VAALERAEDL RRDEVDLAVV AVPNHLHAPV ASGLLRRGVP VFLEKPLCLG SAEAAALTAA
     ERAGGAVLLG GSAARHRADV RALREVAASL GALRHVDVSW VRSRGIPDRG GWFTDRTRSG
     GGALVDLGWH LLDTARVLLR GATGDPEGAE LEHVTGAVSA DFVDDHAFRA AWRGDGAQAD
     PVVGDVEDTA RGFLVTRSGI SIGVRAAWAS HQALDTTVVR VEGSGGTAEL RCTFGFSPNR
     EGPSRLLLTT DGRTTPVELP AEPVGAEYDA QLASLPARLA DPAARGEAAS GARWIAGAIE
     RVYRAADAVR CAERRHAPVD LAPTGAP
//