ID   O85168_PSESY            Unreviewed;      9376 AA.
AC   O85168;
DT   01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1998, sequence version 1.
DT   19-JAN-2010, entry version 51.
DE   SubName: Full=Syringomycin synthetase;
GN   Name=syrE;
OS   Pseudomonas syringae pv. syringae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=99047670; PubMed=9830033; DOI=10.1074/jbc.273.49.32857;
RA   Guenzi E., Galli G., Grgurina I., Gross D.C., Grandi G.;
RT   "Characterization of the syringomycin synthetase gene cluster. A link
RT   between prokaryotic and eukaryotic peptide synthetases.";
RL   J. Biol. Chem. 273:32857-32863(1998).
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DR   EMBL; AF047828; AAC80285.1; -; Genomic_DNA.
DR   PIR; T14593; T14593.
DR   HSSP; P14687; 1AMU.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR006162; PPantetheine_attach_site.
DR   InterPro; IPR001031; Thioesterase.
DR   Pfam; PF00501; AMP-binding; 8.
DR   Pfam; PF00668; Condensation; 9.
DR   Pfam; PF00550; PP-binding; 9.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00823; PKS_PP; 9.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 8.
DR   PROSITE; PS50075; ACP_DOMAIN; 9.
DR   PROSITE; PS00455; AMP_BINDING; 8.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 5.
PE   4: Predicted;
KW   Phosphopantetheine.
SQ   SEQUENCE   9376 AA;  1029854 MW;  F770C08975EF9CE5 CRC64;
     MGGQRVLSKA PFKLEVTDFP EVDGDTEQAI AHLRESFRQP FESVTGQLWE SRLVRCGPQL
     HYWFNRLHHL VADGIGAVLI AHAVSDAYSG LLEGKETLAE GPSYLSFLEE DRAYMASSRY
     KRDRLFWEQS YAQLPPVLLQ RRADFKAGLT NVPAPSDQVQ AMLPRALYNA LTQFASECNL
     SVAHVLVGVI STYFCRTVGV DEIVVGMPVH NRTNARQKAT IGMFSSVSPI RVGFDPHETL
     VDLMNNIGTQ LRRTYRHQRF PIAELNRSLR LAQNGRHQLF DVSLSFESFD GDVTFGSEDP
     ARVLMLDNGY EQTPMAIFVR DYHPSEDIHL DFNFNTAYFT FEEAQRVQQR IFAMLEAVLN
     QHDTPLAHFP LMSTSEHQQL ATFNDTAHPY PRDVLIHQLI EQQAAQRPDA CAVRGDSGPL
     LTYAELNQQA NQLAHRLIEL GVEPDTRVAV SLRRGAEMVV ALLGILKAGG AYVPIDPDLP
     SARQAYMLED SSPQAVLTTR DLSDNLPASD LPVLVLDGHN DRAQLARQQS VNPDAKALGL
     QPNHLAYVLY TSGSTGTPKG VMNEHLGVVN RLLWARDAYQ VNSQDRVLQK TPCGFDLSVW
     EFFLPLLTGA ELVMAPPGGH QDPDYLAQVM SDAGITLLHF VPSMLDVFLE HRSTRDFPQL
     RRVLCSGEAL PRALQRRFEQ QLKGVELHNL YGPTEAAIDV TAWECRPTDP GDSVPIGRPI
     ANIQMHVLDA LGQLQPMGVA GELHIGGIGV ARGYLNQPQL SAERFIADPF SNDPQARLYK
     TGDVGRWLAN GALEYLGRND FQVKIRGLRI EIGEIEAALA KHPAVHEAVV TAREDIPGDK
     RLVAYYTQSA EHTAVDLEAL RSHLQQVLPE YMVPAIYVLL EAMPLTSNGK LDRKALPAPD
     GDALISRGYE APQGEVETLL ASIWADVLKV EQVGRHDHFF ELGGHSLLAV KLIERMRQVG
     LSADVHVLFG QPTVAALAAA AGGGSEVVVP ANLIPEHCDR ITPQMLPLIN LSQAQIDHVV
     KDMPGGVANV QDIYPLAPLQ AGILYHHISA EQGDPYTLKA LFALSDRAQL DDFSGALQGV
     INRHDILRTA VLWEDLDEPV QVVLRQAELH VTELLLDPVD GPVDEQLHQR FDRRHYRLDV
     RTAPLMRIVF SHDPVNDRWL AMLLCHHLVS DATSLSVILQ EIQAHLLGQG NALGEAVPYR
     NYVAQARLGV SEAQHEAFFR DMLGDIDEPT LPFGLQDVQD RGRNLEEASV TLAAELNLRL
     RAQARQAGVS VASLMHLAWA RVLGNVSACE QVVFGTVLLG RMQAGDGADR ALGMFINTLP
     LRVDIGATTV AEGLKATHER LTALLGHEHA PLVLAQRCSG VAAPTPLFSA LLNYRHSVVS
     DVRQKLPGLG GSSLRHRRPY QLPVDLNVDD LGDAFTLTIQ AVQQISATRI GEYMQVALRN
     LVDALEHTPQ AALNSLSILP DDERELLLTG FNDTAHPYPR DVLIHQLIEQ QAAQRPDACA
     VRGDSGTLLT YAELNQQANQ LAHRLIELGV EPDTRVAVSL RRGAEMVVAL LGILKAGGAY
     VPIDPDLPDA RQAYMLSDSA PRAVLTSHEL LADLPDLGVP ALVLDGRDDS ALLKKQPTGN
     PDAKALDLQP NHLAYVLYTS GSTGTPKGVM NEHLGVVNRL LWARDAYQVN SQDRVLQKTP
     FGFDVSVWEF FLPLLTGAEL VMARPSGHQD PDYLAQVISD AGITLLHFVP SMLDVFLEHR
     STRDFPQLRR VLCSGEALPR ALQRRFEQHL KGVELHNLYG PTEAAIDVTA WECRPTDPGD
     SVPIGRPIAN IQMHVLDALG QLQPMGVAGE LHIGGIGVAR GYLNQPQLSA ERFIADPFSN
     DPQARLYKTG DVGRWLANGA LEYLGRNDFQ VKIRGLRIEI GEIEAALAKH PAVHEAVVTA
     REDIPGDKRL VAYYTQTAEH TAVDLETLRG HLQQVLPEYM VPAIYVLLEA MPLTSNGKLD
     RKALPAPDGD ALISRGYEAP QGEIEEQIAV IWQDLLGVEQ VGRHDHFFEL GGHSLLAVSL
     IDRLRKQDLN LNVNTVFTAP SVREMALAIS QEKQALFRAP ANRIPAHCTQ LTPDMLPLVE
     LSVAQIELIA SAVPGGAANI QHIYPLAPLQ EGILFHYLLN LERDAYLVRS TIEFDSRARL
     DAFLEGLQTV IDRHDVLRSS VHWVGLPQAV QVVHRQAQSP IHTLTLRPDE DALSQLDRLS
     DPGRLRLDLR QAPLLLAYIA RDPDSERWLL ALIDHHMISD HVTLELILEE IRLLMRGQSA
     ELLPPQPYRE FVAQTLASPS SAHEAYFTGR LADVDSPTAP FELLEVQGDG NDVEESELAL
     SSDLCARIRT QARERGMSPA VLFHVAWAQV LARCTGRDDV VFGTAVTGRL QGTLGAERAM
     GMFMNTLPVR VQLATQSVQE LVMATHRDLS ELLSHEQASL ALAQRCSSVA TGVPLFSSLL
     NYRHQNEDSQ LQWPGLRLLD SAERTNYPLC LSVNDYGSDL GLLIHSVQPA DPQRLCAMMQ
     CALEQLTDAL AHTPQKEVTQ LDVLPAAERN LLLETFNQTR QDYPTDLCIQ HLFEAQVRTQ
     PDAIAVAFQA QRLSYAELNR QANRLAHHLI GLGIGPDDRV AICVERGVEM MVGLLGVLKA
     GAAYVPLDPA YPAERLAYMI EDSQPAALMT QRHLQEYLPT LTLPLVLLDD DQRKTFTERD
     DNPVVEALGV RNLAYVIYTS GSTGNPKGVM IEHRGLVNYS VDAARLFDLS PTDTVLQQNT
     LNFDLSVEEI FPALLAGATL TPSREIFGSE GTENHGINPT VLHLTAAHWH TLVAEWHKQP
     QVAEQRLQHV RLINVTGDAL SAQKLKLWDE VRPAHTRLIN TYGPTEATVS CTAAYVSHDA
     AAGSEGSGNA TIGKPMANTR IYLLDAHQQP VPYGVAGEIY IGGDGVARGY LNLEEVNAER
     FLADPFSESP DARMYKTGDL ARYMADGRIE YLGRNDFQVK VRGFRIELGE IEARLGNCTG
     VKEAVVIARE DNPGDKRLVA YVVAQPQSQL TAADLRAELA PQLAEYMLPS AFVLLDELPL
     TPNRKLDRKA LPAPDADALI SRGYEAPQGE TETQIVAIWQ DLLGIEQVGR HDHFFELGGH
     SLLAVSLIER LRKQGLNLNV KTVFTAPTVR EMALAISQDK HVLFQVPANR IPAHCTQLTP
     DMLPLVELSV AQIELITSAV AGGAANIQDI YPLAPLQDGI LFHYLLNRER DAYLMRSMIE
     FDSRARLDAF LEGLQTVIDR HDILRSSVHW IGLPQAVQVV HRQAQLPVHT LTLTPEEDAL
     SQLDRLSDPG RLRLDLRQAP LLLAYIARDP NSERWLLALI DHHMISDHVT VELILEEIRL
     LMRGQSADLL PPQPYRDFVA QTLASPSSAH EAYFTRRLAD VDSPTAPFEL LEVQGDGNDV
     EEAKLALNSD LCIRIRTQAR ERGMSPAVLF HVAWAQVMAR CTGRDDVVFG TVVTGRLQGT
     AGAERAMGMF MNTLPVRVQL TTQGAQELVM ATHRDLSELL SHEQASLALA QRCSSVATGV
     PLFSSLLNYR HQGEDNRLQW PGMRLLDGTE RTNYPLCLSV NDYGSELDLI IHSMQPANPQ
     RLCAMMQCAL EQLTDALAHT PQMAVTQLDV LPAAERNLLL ETFNQTRQDY PTDLCIQHLF
     EAQVRTQPDA IAVAVQGQRL SYADLNRQAN RLAHHLISLG IVPDDRVAIC VERGVEMMIG
     LLGVLKAGAA YVPLDPAYPA ERLAYMITDS QPAALLTLPG LQDRLPALSM PLVLLDDEQY
     QGLAECDDNP VVPTLGVRNL AYVIYTSGST GNPKGVMIEH RGLVNYSVDA ARLFDLSQSD
     TVLQQNTLNF DLSVEEIFPA LLAGATLAPS REIFGSEGTE THGIQPTVLH LTTAHWHTLV
     AEWHNQPQAA EQRLQHVRLI NVTGDALSAQ KLKLWDEVRP AHTLLINTYG PTEATVSCTA
     AYVSYDAAAG SEGSGNATIG KPMANTRIYL LDAHQQPVPY GVAGEIYIGG DGVARGYLNL
     EEVNAERFLA DPFSESPDAR MYKTGDLARY MADGRIEYLG RNDFQVKVRG FRIELGEIEA
     RLGNCKGVKE AVVIAREDNP GEKRFVAYVV AQPQTQITAA ELRAELAPQL AEYMLPSAFV
     LLDELPLTPN RKFDRKALPA PADDAFASRE HVEPQGATEI ALAQIWQSLL DLERVGRHDQ
     FFELGGHSLL AMRLISQARH QLGVELGLAA LFAHPEVSAL AVAIAQAGRS KFPDIVPVAR
     DQAWPLSFGQ QRLWFLAQME GASAAYHIPA GLSLHGNLNL KALQRALERI VARHEGLRTT
     FMQGDDGQPV QRISPADTGF NLQMHDLQGL ADAEEKLQAL ASEESLQSFD LQQGPLIRGR
     LIRMAEDHHV LLLTLHHIVS DGWSVDVLTR ELSALYAAFS QDQDDPLAPL ELQYLDYAVW
     QRRWLSGDVL QQQSNFWQQT LADAPALLML PTDRARPALQ DYAGAALPVV FDKDLTRGLK
     ALSQRRGSTL FMTVMAAWAG LLGRLAGQDD VVIGTPVANR TRSEVEGLVG LFVNTLAIRV
     DLSDKPTAET LLARVKQQTL DAQAHQDLPF EQVVEVINPL RSLSHSPIFQ AMLSWENNEA
     SDLTLGDMTL KSIELAADTA QFDLTLDMAE VDEQLVGTLE YATALFDEST MRRYLGYFQR
     VLEAMVADDQ QVLEHVALLG ADEREHLLAG LNATEAPFPQ DRTIHQLFEE RVQAQPDAIA
     VAFGAQRLSY AELNRQANRV AHHLISLGIK PDDRVAICVE RGVEMLIGVL GVLKAGAAYV
     PLDPAYPAER LAYMIEDSTP SALLAQRDVQ AHLPTLDLPL VLLDEDQRTT LSERDDNPVV
     ETLGAHNLAY VIYTSGSTGV PKGVMVEHRG LFAVSAAWEQ LYALHAPLNH LQMAGFFDVF
     SADLIRSLAF GGTLVLCPRE TLMDPPALYR LLSEESIGFA DFVLAVLNAL LGWVEETGHD
     LSFMRTVVCG SDIWTAHSAR QLRKLCGDHV QVVQAYGVTE ASIDSTCFEF EATSQVDGVL
     PIGRALANTR IYLLDELGQA VPPGVAGELY IGGAGIARGY LNLPQLTAER FMDNPFVAGE
     RLYRSGDMAR YRADGNIEFL GRNDSQAKLR GLRLELGEIE ARLAEVAGVR ESLVVIREDS
     GGTPKLIAYF VEYATRDESG PALTPRALRQ QLQLNLPEYM IPAAFVRMAA LPLSANGKLD
     RRALPEPDAD AFDQHDFEAA DGPLETAIAA IWADVLGVAQ VGRHDDFFAL GGHSLLVMRV
     LAQVRQQLNL EVSPSVFFAA PVLRQFAERL GNTQDNARVA IKPVQRSGAL PLSYAQQRLW
     FLAQLEGGSA AYHIPAGLRL RGNLDQASLQ RALDRIVARH EALRTTFVQE QGQPAEQRIS
     AAETGFRLQL QVLAGQTDAE DKLLAIAAQE ASEHFDLVNG PLVRGRLVRM ANDNHVLLVT
     MHHILSDGWS TGVLNRELGA LYAPFRQGAG DPLPALPVQY VDYALWQRDW LSGDVLQQQR
     QYWQQALAGA PALLTLPTDR PRPAQQDYSG QTLELVLDTQ LTRGLKALSQ RHGSSLFMTV
     MGAWAALLGR LSGQDDVVIG TPVANRMSAE VENLIGFFVN TLAIRVDLSG TPSVEALVRQ
     VKQRTLAAQA NQDLPFEQVV EVVQPQRSLS HSPIFQAMLS WQNNEDTALV LGDLTLQGVA
     VAGDTAKFDL ALDIGEVDGQ LIGTLEYATA LFDESTMRRY RGYFLRLLEA MAADDQQVLE
     QVPLLDTAER EYLLKDINAT ERTYPVGQLM HRLFEAHAEA APQAIAVRQG EQTLTYAELD
     SRANALAQHL RKHGVGPGTR VAILLDRSVE LLASMLATLK CGAAYLALDR LAPEERLRFM
     LEDSEAIMLL SRSDLTAPDM TPRLDLDTLE LSALNQEPVV PATEVAGETP ACIIYTSGST
     GVPKGVIVTH NGIVRLVQDN GYYDFSAEDR VAFSSNPAFD ASTPEIWGAL LNGCQSVIIE
     PQVLLEPVAF AALLKRHGVT AMISSTALFN LYAGLIPEAL AGLRMIMCGG ERADPASFRR
     VREHSAQVRL FNGYGPTEGT TCATSYEIFD VLPDTLSLPI GKPNANVRVY VLDARREPVP
     MGVVGDIYIG GTGVALGYLN RPELTAERFS EDPFSQQAGA RLYRTGDLAR WLPDGNLEYL
     ARNDGQVKVR GFRVELGEIE SVLHLYDGVR NSVVVAHEAS PGDTRLVAYY TVHAGVAAPD
     PEDLRAQLSA DLAEYMVPSV FVRLDALPLT LNGKVDQKAL PVPDLNAMFE RTYVAPEGAT
     EQALAEIFQE LLGLERVGRH DGFFELGGHS LLAAQLVSRV RQQLNGDMAL RQLFNHPTVA
     ELAKVVDGLQ TVDSDSIEPI ERNAPLALSF SQQRLWFLDR LDPGASSAYH MPMSLLLRGE
     LDHRALKAAL DRLVARHESL RTTFELHGEQ PVQVIAAADS GFALAEDDLR SQPYEQASLN
     ASRIADSEAA APFDLRQGPL IRGRLLRLAD DEHMLLITQH HIISDGWSVG VLINEFTALY
     QAFTEQRPDP LPALSIQYAD YAAWQRRTFT GERLAEQADL WREHLGGAPT LLSLPTDRPR
     PVVQSYRGGA VPVTIDAALH QRLERFCQAH NVTLFMGLLS AWSVLMTRLG NERDVVIGVP
     SANRGRTETE NLIGFFVNAL ALRVDLTQNP SVAQLLEQVR QTTLAAHEHQ DIPFEQVIEA
     LQPPRSMSHS PLCQVALSLD NTSIGGELKL PGLSLHPVLQ AHETAQFDLM LTLASENGAL
     NGVIEYASDL FDRSTVERFA QHFHTLLEAM VEDVAQPVLG LPLLSPAQRL ASPALLQPKA
     VFASGLMVHQ RFEQFAAAHP QNIALVFGRH EVSYQALNRR ANRLAHELLA QGVRPDDRVA
     ILAERGTQMI CAVLAVLKSG AAYVPLDPTY PTERLGYLLT DSAPVALLAQ SACLDVLPAH
     SVPVLTLGAD NDSADLADES VDRNPEPAAL GLSREHLAYV IYTSGSTGLP KGVLVEHGNV
     ARLFDATAGQ FNFGHEDVWT PFHSFAFDFS VWEIWGALCY GGKLVIVPSE VARSPDDFYA
     LVCEQQVTVL NQTPSAFRQF IQARERSPQE HALREVVFGG EALDFRSLQP WTARTPLSRT
     RLVNMYGITE ITVHATYYPI SQSEIDTAMP SLIGPALDDL CLRILDDYQQ PVPVGVNGEI
     YIGGAGVARH YLNRTELNAE RFIADPYALQ SGARLYRTGD VAHYRSDGGV VNVGRNDSQI
     KIRGFRIELG EIEAQLLACP EVREAMVILR EDRPGDKRLV AYLIAEDGAA PESALLRSQL
     ASVLAEHMLP SAFVTLETWP LTTNGKLDRA ALPAPDQFAT VSRDYEAPLG AIETTLAAAW
     QELLGVERVG RQDHFFELGG HSFLVISLIE RLRQIGLLLD VSTVFSAPTL QAMAAVLAGG
     TAAERVAPAN LIPVDCTALT PDMLPLVKLT RQELEHIVAD VPGGVANVQD IYPLSSLQEG
     ILFHHLLQSE GDAYLMRTLA TFDSRALLDK FLGALQVVIN RHDIMRSSLR WQGLPQPVQV
     VHRQAQLPVI QLDTAPGEDA LQMLRERTNT YHMRLDLQQA PLIAAYITYD TRQEKWLMAL
     LDHHLISDNV TLRLIMGEIQ AVMDGRADAL PPSQPYRNFI ARAACVSQAE HEAYFRQLLG
     DVDTTTAPYG VLDVRGGDAT ILRSVQDLSD DLSARIHSTA RAQGVPTSVL FHAAWGLVVA
     ATSGRDDGIF GTVLSGRSQG TSGANHALGM FINTLPMRIR LQQNSVRDIV QDAYQQLSGL
     LTHERAPLAL AQRCSAVDAS LPMFTVILNC RHGDLVNTAG ENIEDMGEEQ EGVHFLGSET
     RTNYPIEIAV ANEANGFSLT AQSIDGIDPH RIAAYLGQAV AELVNALEQD PARLASSLEV
     IPQAERQLLL NDFNDTASDF APAVPIHALF EDQVRRNPDA VALVYEDRQL SYRQLNRRAN
     HVARQLLQLG VQPDERVAIC AERSLDMIAG LLGVLKSGAA YVPIDPAHPA DRMAFMLQDS
     QPRALLTQGA LSLPVGDTPL MLLDSAESLL AADDQAFDAN PVVDGLTAEN LAYVIYTSGS
     TGQSKGVMVE HRSVFNFWNV LTRTTHQHCP TPATVALNAG FFFDMSIKGI SQLFSGHKLV
     IIPQLLRANG SELLDFLEAH QVHAFDSTPS QLDTLLSAGL LERSSYQPVS VLLGGEAINA
     STWEKLRNCP TIRLYNMYGP TECTVDATID LIRDLGEKPS IGRPIANVQV HVLDARGEPA
     PLGVAGEIHI GGSGVARGYL NRDELSAERF IVDPFSDAAN ARLYKTGDLG RWLADGTLEY
     MGRNDFQVKV RGFRIELGEI ENVLLAVPGI REVVVIARND SQGDSDSQRL VAYVCGESVA
     AEHLRSELLR HLPEYMVPSA FVQLDALPLT ANGKLDRRAL PAPGQDALAS KVYEAPQGET
     EEAIAEIWKA LLHLDQVGRN DGFLELGGHS LLAVQLLSRL RRKLGTRITL RELFDAPTVR
     GLASLVNAAA PGEAQSIPRA NRSGRLPLSF SQQRLWFLDH LDHAAGAAYH LPMALRLTGA
     LDTAALEATL DRLVARHETL RTRFELVDGE PVQKIAPADS RLPLLKQDLR DLSGDERTST
     LARLGQENAT QLFDLTKGPM LRGHLLRVAD AEHVLLITLH HIVSDGWSNS VLAQEVSALY
     AAFSQGQKDP LPALPLQYVD YAAWQRQSLD GPALQAQIDF WRKHLEGAPS VLNLPLDRPR
     PAIQSYTGGM VEHVFSPALS ADLRAFSQAQ GSTPFMVLLA GWSMLMSHLS EQTDVVVGTP
     VANRQHPELE PMIGFFANTL ALRVATDRET RLNDMLDRIK SLTLAAYNHQ DLPFEQVVSA
     LQPTRNVSHS PLFQVMLSLD NTPPSLLQLP DLEVELLDSE HHTTQFDLSL SLVDSSESLG
     GGLQYSSDLF DKTTAQAIMQ LFARVLENMV SDARQSIGQV LDNTPALPRS AHTATIAATV
     EDEQPEALPY EAPEGETEIA LANLWKELLK LEKVSRHDDF FKLGGISLMA VQMASRLRKV
     LGKPIAVRDL FIEPTIAGFA RTLDGQARPG QHSNLVPVRR TGSQRPLFLV HPLGGEVQYV
     RDLAAAIDPQ VPLYGLAASG LAAGETPLYE VPAMAARYLA AIRQVQPKGP YRIGGWSAGG
     LIAYEMARQL QSSGEKLEFL GIIDTSARLE QQAPEALSEG QFLMDWLPEQ LDPEVFRQLT
     ELAGTDAIDE MLALCMAHRL LPEELPQDVD ATLLRSHLAV AHATHIAIGN YVSPPAPLTV
     TLFTASAEER DDPLLGWTAL LDSPVNVTEL PGTHETLVRA PQVSALGQAI SRALNKEPNQ
     EPRREEVLRS ITAPAE
//