ID   O87704_BACSU            Unreviewed;      2571 AA.
AC   O87704;
DT   01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1998, sequence version 1.
DT   19-JAN-2010, entry version 47.
DE   SubName: Full=Fengycin synthetase;
GN   Name=fenD;
OS   Bacillus subtilis.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=F29-3;
RX   MEDLINE=99369881; PubMed=10438779;
RA   Lin T.P., Chen C.L., Chang L.K., Tschen J.S., Liu S.T.;
RT   "Functional and transcriptional analyses of a fengycin synthetase
RT   gene, fenC, from Bacillus subtilis.";
RL   J. Bacteriol. 181:5060-5067(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=F29-3;
RA   Chen C.;
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AJ011849; CAA09819.1; -; Genomic_DNA.
DR   HSSP; P14687; 1AMU.
DR   SMR; O87704; 450-958, 962-1478, 1943-2076.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR010060; NRPS_synth.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   InterPro; IPR006162; PPantetheine_attach_site.
DR   Pfam; PF00501; AMP-binding; 2.
DR   Pfam; PF00668; Condensation; 3.
DR   Pfam; PF00550; PP-binding; 2.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 2.
DR   TIGRFAMs; TIGR01720; NRPS-para261; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 2.
DR   PROSITE; PS00455; AMP_BINDING; 2.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine.
SQ   SEQUENCE   2571 AA;  290801 MW;  83098B3ADA4BD488 CRC64;
     MTQATQIQDI YPLSYMQEGM LFHSLLDFSS KAYVEQTSFT ITGSLCIDSF QKSLNLLVSR
     YDIFRTIFIK EVPDLTGPQQ VVLTNRELTV QREDLSHLKH DEQLALIEDF MQQDREKGFH
     LQKDPLMRLT LFDRGDSTYT CVWTHHHIIM DGWCLGIILK EFFSMYDSLK NNRPVQLDST
     VPYSRYIEWL GEQDQEETAA YWRDYLQEYG NTASIPKLKS RSANGEYEAA NIRLSLEPAI
     VQKLTAAAQN WGVTLNTLFM SLWGVLLHRY NGTDDAVFGS VVSGRPSAID GIESMVGLFI
     NTVPVRIRSA EKMAFSTLVK SVQEDTLRSE QHGYYPLYEI QNSSALKQGL IDHILVFENY
     PVQLQQAVNR QSENDENALK LDDISMSEQT SYDLNVVIVP GESFYIKFSY NAAVYEREEV
     LRIQGHLMEA MDCILSNPDI AVDSINIVPT EERKLIQSFN ETERHYPNKT LSQLFEEQAL
     KTPDAAALRM GDECRTYRQL DERANQIAHA LIEKGAGSGG IVAVMMERSM DMAAALLGIW
     KAGGAYLPLD PSYPKERLSF LLHDSQAALL LTEEELISSI PSGYEGSIVT SGHTTHYRTD
     SPDASIGELA YLIYTSGTTG RPKGVLVDHQ GIANTLQWRR EEYGMSEGDT ALHLFSYVFD
     GCVTSLFTPL LSGACVLLTT DNEAKDVLAL RRKIAQYKVS HMLIVPSLYR VLLEVLTAED
     AKSLRIVTFA GEAVTPDLLE TSRKICPSAE LANEYGPTEN SVATTILRHL NEEERITIGH
     PIANTKVYIL QGEQLQPIGA AGELCISGAG LARGYYKRTE LTEKAFTDHP FLKGERLYRT
     GDAGRFLPDG TIEYIGRFDD QVKIRGYRIE LSEIETVLRQ ASGVKEAAVL ARDVSDEEKE
     LVAYIVPEKG NGLPNLHQHL AGTLPSYMIP ASIIKITQMP LTSSGKLDRS ALPEPENTTS
     LTYMPPQTLM ETELARIWEE GLNKNQIGIR DDFFQLGGQS LKAATLVSRI HKRLNIELPL
     SDVFSYPTVE SMAAKLMSLH EHAFMQIEPA DFRDVYPLSF SQKRLYALYQ LADDSTGYNM
     PAVLELRGHL DRGRLRKVLT ELVNRHESLR TAFELNNGEP VQKIHPALTA DLKELEIDSE
     QMLQSAISSF IKPFDLTAGP LFRASLISLE KERAYLLLDM HHIIADGISM STLVQEFTDL
     YCGKELPALN LHYKDFAVWQ QEKFPETHYS KQEAYWLKQL GGSLPVLDLP LDKTRPLLPD
     FSGGTFEVNI DKRTAEELHR LMFETGTTMY MLLLAVYSIM LSKLSGQEDI VVGSPAAGRP
     HADLERVIGM FVNTLAMRCQ PEGRKTFSSY LQEIRELALT AYEHQDYPFE ELVNKLETKR
     EVNRNPLFDA MLVLQNSEDF QFEVPGLSIS SVTPSHNVSK FDLTLHAEEH SNGIRCRFEY
     STALFEEETI ARWASHFIEL VKGITSDIHM KLSEMQLLSA PARELLLETM GQYADYPRDE
     SIVRLFEKQA AEHPEHTAVV CDHIRLTYRD LNEKAERTAT MLMKQGVRSG DIIGLMFDRS
     PDMVIGVLSI LKAGGAYLPI DPEYPQERIS FMLNDSGARI LLTEHGHNKP ADYHGQILYL
     NDAENELISP DLKAQETLAD QPAYVIYTSG TTGQPKGVVV EHRNVISLLK HQDLPFDFGS
     EDVWTLFHSY CFDFSVWEMF GALLNGSTLV VVSRETARDP NAFRLLLKNE GVTVLNQTPT
     AFYGLIHEEE NHTDRLHVRY VIFGGEALQP GMLVTWNEKY PDTDLINMYG ITETTVHVTY
     KKLSSADIEK NKSNIGKPLA TLQAYVMDAH MNLQPTGVPG ELYIGGEGVA RGYLNRDDLT
     AARFVPNPYL PGDRLYRTGD LAKRLASGDL EYMGRIDDQV KVRGHRIELG EIQASLLQLP
     IIKEAAVITR DDEQGQSAVY AYLVAEDGQV VNEADIRAAL RAVLPDFMVP ARLIQIDSIP
     LTVNGKLDQK ALPEPDKRAQ AENDISPRNE IEKAMADIWE ELLEAEEIGV SANFFELGGD
     SIKALQVCAR LKQRGYETTV REMFEHQTLG ELSARVRKAV RVIDQTPVEG ELPWTPVQQW
     FFSQSLETHH FNQSVMLYRA ERFDDIALRN VLRSLVTHHD ALRMICRYKD GKPVQVNRGA
     DLPDEELYAF DLFDIRDHRS NTAGNAQGLS AEAHKQIEEM ANQIQRTIRL ETGPLLHAGL
     FKAEDGDHLF LTIHHLVIDA VSWRILFEDF SIAYEQAVSG KPIVLPEKTD SYFTYAQTLA
     DYSKSRRLQR EIAYWNERED RHIERIPTDH TITSNSFKDT EVIDFELSRE DTELLLTAAN
     NAYNTETNDI LLTALGLALQ EWTGFDHFKI SMEGHGREDY LDNIDMNRTV GWFTSIYPVW
     LDMSDSDHTD EGERLGRHIK QTKDMLHRIP HKGAGYGVLK YINKIWDSEY SDPEISFNYL
     GQFDQDVQSK AFEISDIKTG NEISPDWERP YVLDISGAVS SGCLHMHIIY NRLQFKKQTI
     QALADHFKHA LENMIQHCTG KENREWSAAD FTDEDLTLED LSEIMGAVNK L
//