ID   Q52400_PSESY            Unreviewed;       614 AA.
AC   Q52400;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 2.
DT   19-JAN-2010, entry version 55.
DE   SubName: Full=Syringomycin biosynthesis enzyme 1;
GN   Name=syrB1;
OS   Pseudomonas syringae pv. syringae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=B301D;
RX   MEDLINE=99047670; PubMed=9830033; DOI=10.1074/jbc.273.49.32857;
RA   Guenzi E., Galli G., Grgurina I., Gross D.C., Grandi G.;
RT   "Characterization of the syringomycin synthetase gene cluster. A link
RT   between prokaryotic and eukaryotic peptide synthetases.";
RL   J. Biol. Chem. 273:32857-32863(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=B301D;
RX   MEDLINE=95332206; PubMed=7608074;
RA   Zhang J.H., Quigley N.B., Gross D.C.;
RT   "Analysis of the syrB and syrC genes of Pseudomonas syringae pv.
RT   syringae indicates that syringomycin is synthesized by a thiotemplate
RT   mechanism.";
RL   J. Bacteriol. 177:4009-4020(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=B301D;
RA   Zhang J.-H.;
RL   Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=B301D;
RA   Gross D.;
RL   Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; U25130; AAA85160.2; -; Genomic_DNA.
DR   HSSP; P14687; 1AMU.
DR   SMR; Q52400; 15-523, 538-607.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
SQ   SEQUENCE   614 AA;  66144 MW;  22E77CD3A7B63388 CRC64;
     MPITNTDESL SAASAPLKPG AFLHEIFSDR ARQFPERTAV SDAARTLSYA QLDALSTKLA
     ARLRDEGVTY GTRVGMYLPR SVDLVTSLLG ILKAGGTYVP VDPQYPGKRV EHIVRDSELS
     LIIGDAANLP KISSLRVLAL DELLSAPALQ PAAQDTRIDP NNSTAYIIYT SGSTGEPKGV
     QVSHGNVSRL LESTQRAYGF NAQDVWSMFH SIGFDFSVWE IWGALAHGGQ VAVVPYDISR
     SPAALRQWLA DQRITVLSQT PSAFRGLDEA DRGNTAPLAL RYVVLGGEAL PASVLRPWVE
     RHGDQKPALI NMYGITEATV HTTFKRVLAQ DLETAAMVSL GKPLDGWRLH LLDANQAPVA
     AGTTGELYIE GAGVAQGYLN REALNVERFV ELPGAVRAYR TGDLMTLESN GEYRYAGRCD
     EQLKISGFRI EPGEIEASLQ TSPSVAAAHV GVHDYGDGDL RLVAYVVPGQ GVDAWTEQAR
     SEVAALMAEN LPGYMRPSVY VPLAELPVTH HGKIDKQQLP SPAAGTALSG AADVKGLSEQ
     EHFVLKVWSE DLGLKNIGVN DDFFDSGGTS LALIRSLSKL KTHYKINLDP GILADGATAK
     VLADHITRSL VQAH
//