ID   Q54491_STRNO            Unreviewed;       262 AA.
AC   Q54491;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   19-JAN-2010, entry version 50.
DE   SubName: Full=SnoaD;
GN   Name=snoaD;
OS   Streptomyces nogalater.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=38314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 27451;
RX   MEDLINE=96242142; PubMed=8668120; DOI=10.1007/s004380050147;
RA   Ylihonko K., Tuikkanen J., Jussila S., Cong L., Mantsala P.;
RT   "A gene cluster involved in nogalamycin biosynthesis from Streptomyces
RT   nogalater: sequence analysis and complementation of early-block
RT   mutations in the anthracycline pathway.";
RL   Mol. Gen. Genet. 251:113-120(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 27451;
RX   MEDLINE=98007868; PubMed=9349712; DOI=10.1007/s004380050562;
RA   Torkkell S., Ylihonko K., Hakala J., Skurnik M., Mantsala P.;
RT   "Characterization of Streptomyces nogalater genes encoding enzymes
RT   involved in glycosylation steps in nogalamycin biosynthesis.";
RL   Mol. Gen. Genet. 256:203-209(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 27451;
RX   MEDLINE=96349102; PubMed=8760909;
RA   Ylihonko K., Hakala J., Kunnari T., Mantsala P.;
RT   "Production of hybrid anthracycline antibiotics by heterologous
RT   expression of Streptomyces nogalater nogalamycin biosynthesis genes.";
RL   Microbiology 142:1965-1972(1996).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 27451;
RA   Palmu K., Hautala A., Kunnari T., Hakala J., Mantsala P., Ylihonko K.;
RT   "Identification and fuctional analysis of a glycosyltransferase gene
RT   (snogZ) and a resistance gene (snorO) from the nogalamycin producer,
RT   Streptomyces nogalater.";
RL   Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 27451;
RA   Ylihonko K.P.J.;
RL   Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family.
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DR   EMBL; AJ224512; CAA12013.1; -; Genomic_DNA.
DR   PIR; S69225; S69225.
DR   HSSP; P25716; 1Q7B.
DR   SMR; Q54491; 1-262.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002198; DH_sc/Rdtase_SDR.
DR   InterPro; IPR002347; Glc/ribitol_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR19410; ADH_short_C2; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
SQ   SEQUENCE   262 AA;  27420 MW;  5814CF204941DA60 CRC64;
     MPDTDGRVAV VTGGTSGIGL AVVKALAATG YACRSLCARS QDAVDSTVEE LRDEKLEVDG
     RSCDVRSTDD VREFIGFATR RFGGVDVLVN NAGRNGGGPT ARITDELWLD VIETNLTSVF
     RVTREVLTTG GMLAAGRGRI INIASTGGKQ GVVLGAPYSA SKHGVVGFTK ALGLELAKSG
     ITVNAVCPGY VETPMGERVG RGYAEVWDTS EEAVLERFQA KIPLGRYAQP EEVAGLVTYL
     TTPTADSITA QALNVCGGLG NY
//