ID   Q8GHB8_9ACTO            Unreviewed;       501 AA.
AC   Q8GHB8;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   19-JAN-2010, entry version 33.
DE   SubName: Full=Acyl-CoA synthetase;
GN   Name=cloN4;
OS   Streptomyces roseochromogenes subsp. oscitans.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=149682;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DS 12.976;
RX   MEDLINE=22368916; PubMed=12480894;
RA   Pojer F., Li S.M., Heide L.;
RT   "Molecular cloning and sequence analysis of the clorobiocin
RT   biosynthetic gene cluster: new insights into the biosynthesis of
RT   aminocoumarin antibiotics.";
RL   Microbiology 148:3901-3911(2002).
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DR   EMBL; AF329398; AAN65233.1; -; Genomic_DNA.
DR   HSSP; P14687; 1AMU.
DR   SMR; Q8GHB8; 4-491.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR020459; AMP-binding.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   Pfam; PF00501; AMP-binding; 1.
DR   PRINTS; PR00154; AMPBINDING.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding; Nucleotide-binding.
SQ   SEQUENCE   501 AA;  53699 MW;  F221FE631B362C0F CRC64;
     MSDRRGLHDL LAASAARTPN APAVIGPAGS MSYGELDERA NDLAGRLSGR GIEKGDRVLI
     WSPKSANAIA AMQAVLRLGA IYIPVDPLTP PERFAAIARE SGALALCAPD DLSARVPSPL
     RDRLACVDLD AAPVPNALPT APVNTRVEPD DLAYILYTSG STGTPKGVCV SHRSALAFID
     WAVAELAPGP QDRFANHSGL SFDLSVLDLY AAFTVGAAVC PIHAEFAYAP ERLVEFLHRE
     RISVWYSVPS VLILMLRDGG LLDRPAPETL RALLFAGEPF PIGYVRALAA WSDARLLNLY
     GPTETNVCTY HEVRPADLAR DLPVPIGRPC SGDRVWARRP DGSEAEPGEE GELVVSGPTV
     FAGYWGRQPQ EGPYATGDRV KVRPDGSFDY LGRHDDMVKI RGHRIELGDV VAALNSHPGV
     AEAAVVAVGE GLDRNLAAFV IRSQGSSFGN VALRRHLADR LAPHMIPGDI RFVDQLPHND
     RGKLDLAALQ IPLHGAQKVQ G
//