ID   Q8KUI0_ACTPA            Unreviewed;      1005 AA.
AC   Q8KUI0;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   19-JAN-2010, entry version 35.
DE   SubName: Full=Cytochrome P450;
GN   Name=asm30;
OS   Actinosynnema pretiosum subsp. auranticum.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Pseudonocardineae; Actinosynnemataceae; Actinosynnema.
OX   NCBI_TaxID=42198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 31565;
RX   MEDLINE=22056096; PubMed=12060743; DOI=10.1073/pnas.092697199;
RA   Yu T.W., Bai L., Clade D., Hoffmann D., Toelzer S., Trinh K.Q., Xu J.,
RA   Moss S.J., Leistner E., Floss H.G.;
RT   "The biosynthetic gene cluster of the maytansinoid antitumor agent
RT   ansamitocin from Actinosynnema pretiosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:7968-7973(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 31565;
RA   Yu T.-W., Bai L., Clade D., Hoffmann D., Toelzer S., Trinh K.Q.,
RA   Xu J., Moss S.J., Leistner E., Floss H.G.;
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AF453501; AAM54108.1; -; Genomic_DNA.
DR   HSSP; P14779; 1JPZ.
DR   SMR; Q8KUI0; 6-461, 481-1005.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017973; Cyt_P450_C.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR003097; FAD-binding_1.
DR   InterPro; IPR017927; Fd_Rdtase_FAD-bd.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR015702; NADPH_Cyt_P450_Rdtase.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD_bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19384:SF17; NADPH_Cyt_Red; 1.
DR   Pfam; PF00667; FAD_binding_1; 1.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   4: Predicted;
SQ   SEQUENCE   1005 AA;  108751 MW;  647E9EDA09935708 CRC64;
     MVATGTRIPG PKPLPLVGNL LDVLTSDLDT DVDFLDRCHR EHGGIVALTF AGQRQVFASS
     HELVARMCSD PSWGKAVHPA LEQVRDFAGD GLFTARGDEP NWGKAHRLLM PAFGPTAMRD
     HFPAMLDIAE QMLVRWRRFG PDHRIDVADD MTRLTLDTIA LCAFGARFNS FYRDRAHPFV
     DAMVRSLVEA GERAERLPGV QPFLVGRNQR YRDDIATMNR IADGIVAARA ALPAGERPDD
     LLERMLTCAD PVTGERLSAR NVRYQLATFL IAGHETTSGL LSFAVHRLLA HPEVLRKAKD
     AVDGVLGDRV PAFEDLARLD YLGQVLRETL RLHPTAPAFA LAPDEPAELG GHAIGAGEPV
     LVMLPTLHRD PAVWRDPDVF DPERFAPERM DEIPACAWMP FGHGARACIG RPFALQEATL
     VLALVLQRFD LALADPDHRL TIKQTLTLKP DSLVVRARPR ADRPGATATV ETVVPHQVPA
     THRHGTPLHV FYGSNGGSGE GLARTIAGDG AARGWATSVA PLDDAVRALP ASGPVVIVSS
     SYNGAPPDNA AHFVRWLTQD GPDLSGVDYL VLGCGNLDWS ATYQRVPTLI DEAMAAAGAR
     RLRERGATDA RADFFGDWER WYEPLWPLLS AECGVEVGEI GPRFRVVESD AADGLGDLAS
     AVVLENRELV RGPDAGSKRH LELRLPDGTS YRTGDYLSVL PQNHPDLVRR AVARLGTRAE
     RVVTVESSAP TGLVPVGRAL RVDELLTRCV DLSAPAGAGV VARLAERCPC PPERAELAAT
     TGATLLELLE RFPSCAVDLA LALELLPAPR TRLYSISSAA EEQRAEVALT VSVTGVTSGY
     LSRVRPGDRV AVGIASPPES FRPPADNTVP VVLIAAGTGI APFRGFLRAR AALGGEPGPA
     LLLFGCRGPE LDDLYAEEFA ALGDWLEVDR AYSRHPDGEV RHVQHRLWQR RDRVRELVDA
     GARVYLCGDA TRVGPAVEEV LGRIGPGAGW LDALRAGGRY ATDVF
//