ID   Q8RJY1_STIAU            Unreviewed;      2218 AA.
AC   Q8RJY1;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   19-JAN-2010, entry version 43.
DE   SubName: Full=StiF protein;
GN   Name=stiF;
OS   Stigmatella aurantiaca.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Cystobacteraceae; Stigmatella.
OX   NCBI_TaxID=41;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Sg a15;
RX   MEDLINE=21935336; PubMed=11809757; DOI=10.1074/jbc.M111738200;
RA   Gaitatzis N., Silakowski B., Kunze B., Nordsiek G., Blocker H.,
RA   Hofle G., Muller R.;
RT   "The biosynthesis of the aromatic myxobacterial electron transport
RT   inhibitor stigmatellin is directed by a novel type of modular
RT   polyketide synthase.";
RL   J. Biol. Chem. 277:13082-13090(2002).
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DR   EMBL; AJ421825; CAD19090.1; -; Genomic_DNA.
DR   HSSP; P96202; 1PQW.
DR   SMR; Q8RJY1; 27-901, 1477-1789, 1810-2170.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR001227; Ac_transferase_dom.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPlipase.
DR   InterPro; IPR013154; ADH_GroES-like.
DR   InterPro; IPR013149; ADH_Zn-bd.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR011032; GroES-like.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   InterPro; IPR020842; PKS/FAS_KR.
DR   InterPro; IPR020801; PKS_acyl_transferase.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_reg.
DR   InterPro; IPR020807; PKS_dehydratase.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR013968; PKS_KR.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR016038; Thiolase-like_subgr.
DR   Gene3D; G3DSA:3.40.366.10; Ac_transferase_reg; 1.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 2.
DR   Gene3D; G3DSA:3.40.47.10; Thiolase-like_subgr; 2.
DR   PANTHER; PTHR11712; Ketoacyl_synth; 1.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF08659; KR; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00827; PKS_AT; 1.
DR   SMART; SM00826; PKS_DH; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE   4: Predicted;
KW   Transferase.
SQ   SEQUENCE   2218 AA;  237401 MW;  B85339D5457FA4F5 CRC64;
     MSSFLERVAE LSPEKRAALA ELLRLAPEPI AIVGMACRYP GGVKDSDSYW DLLKRGGDAV
     TEIPAARWDI NAFYDPNQDS PGKTTTRWGG FLDDVEGFDP HLFGISPREA ASMDPHQRLF
     LEVAWEALEN AGQQTDRLAG SKTGVFVGLY TSDYSPVVLS DLNAINVYTG TGTANNVAAG
     RLSYLLDLQG PSFVVDTACS SSLVAVHLAC QSLLNRECRM AVVGGVTLLL TPLTLVMASK
     MQLMAADGRC KTFDSRADGI AMGEGCGVVI LKRLSDAQAD GDRILAVIKA SAINQDGRTN
     GLTAPSGASQ QVLLRQALTR AGISPSQVTY VEAHGTGTPL GDPIEVEALA EVIGQPRPSG
     PPCVLGSVKA NLGHTGAAAG VAGLIKVVLS MQNEAIPPQL HYRELNSNIS LENTSLVIPK
     ELHPWPAGKG PRIAGISAFG WSGTNAHVLV EEAPAAPKAR AAVERPVHLL TLSARTEAAL
     REFAERVKTY VSAHADLPIA DLCYSANTGW SKFEHHLAVP AGTTAQLSER LSAFLEGQPQ
     AGTSYGQVTG RRGPGVAFLF TGQGSQYAGM GRQLYQTQPT FRRALDRCDE LLRPLLGRSI
     LSVIYPEAGQ ASPIDETAFT QPALFAFEWA LAELWRSWGV VPTVVMGHSV GEYVAACVAG
     VFTLEEGLAL IVERARLMQS LPPGGEMAAV FTDGARTAQA IAPYASQVSI AAFNGPSETV
     ISGDGKAVEA ILGALSAEGV KVRRLGVSHA FHSPLMDPML DAFERAAAKT RFMPPKITLI
     SNLTGGPSEE FSARALRRHA REPVRFSDGM AALKARGVSV AVEIGPNATL LGIGSRCLPE
     GSVAWLPSLR KDKDEWEVLL ATLGALSVRG VPVNWAGFDS DYPRRRVSLP NYPFQHERFA
     LKQMDGRGVA PSGQVVGHPL LGSRLRVATV DGTLFESKFR ADEPSFFSEH RVYGMSTVPA
     TAYLEGALAA AEEIFGAGEH ALESVDIQEA LVLSDAPRTV QYLIGSREEG GTARFQVFSL
     ASSGSGSEGV WTTHSSGQIR IASGAEPLSG TPLTPEQALE AIRTRCPRGL EPRAFYDWLE
     GQGLEYGPRF RGVQQVWRGD GEALGLVELP ESAVDEAKAF KVHPGLMDAC VQLFGVIEYR
     EGAQDDTEVY LPVSIDRYRL KGRLGSKVWS HARIRPSEGT ARETLKADIR LYDEAGRIVA
     EVEGMCIKRA PREMLARFGQ AQFSNWLHEV EWKEEVRSAA AGAARPGSCR WVVFADRSGV
     AEALIDRLTA RGEPVVRVLA DDHYSREGDL VRLHPEQPEH VRSLMESAAS SGGAVTRYLY
     LWGLDSSGPV SRGEASRVDT RAIGSNPLLH LVQELAGQQG SHQLFLVTRG AQATTREHAP
     IDAFQASLWG FARTIAFEHP ELRPVRIDLE PSRKGGSPRE TEILLGEVTR SDAASAEDAI
     AFRGSLRLVS RLMRQAKRAS SNRKLRIPPA PAFRLEISQR GTLEDLTVRP VERRPPGPGE
     VEIRVRATGL NFRDVLNALG MYPGDPGLLG GECAGVISAI GPGVEGFKVG DPVVAVISLG
     SFATYCTVLA DFVAHKPAAL SFAQAAAIPI AFLTAQYGLQ QLGRMAAGSR VLIHAAAGGV
     GMAAVQLAKR AGAEVFATAS SGKWDVLEAM GVEHRMNSRT LDFADEVMAR TEGQGIDIVL
     NSLADDFIPK SLSVLRSGGR FLEIGKRGVW TSAQVAERYP GVSYAIYDLG EVGTKDPSII
     RSMFRALMAE FEQGTLVPPP LRVFALQDAV EAFRHMALAK HVGKVVITVN DGAPESAETT
     ARAGAAVPIR GDSTYLITGG LSGLGLKTAQ WMARRGARHL VLVARSEPGP EALGVIGELE
     LSEVQVVVAR GDVSRIDEVR GILDRVRDSL PPLRGIVHSA GVLDDGVLRQ QTAGRFDRVL
     APKAGGAWNL HLLTRDLPLD FFVLYSSIAS MFGSASQGNY AAANAFLDAL AHHRRALGLA
     GLSINWGAWS EAGMAARLSQ RDMNRLSGQG IGTIAPDQGT QVLEMLLGQD AAQVGVLPID
     WGTFFQRNPA SKTSPFFSSL EGGTSVKKAA PTQVPSDILP RLREAAVGRR EQLLSAHIRE
     QAIKVLGLNP SHPLNPLQPL NEIGLDSLTA VELKNALGRT LGSSLHATLL FDYPTIDALT
     RYLAKEVMGW SAPALAPEAA EGAEDAEKAR RVAEIQQLSD DEVAASINEE LAALRQES
//