ID   Q93NX6_9ACTO            Unreviewed;       396 AA.
AC   Q93NX6;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   01-SEP-2009, entry version 36.
DE   SubName: Full=AmphL;
GN   Name=amphL;
OS   Streptomyces nodosus.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=40318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=21344785; PubMed=11451671; DOI=10.1016/S1074-5521(01)00046-1;
RA   Caffrey P., Lynch S., Flood E., Finnan S., Oliynyk M.;
RT   "Amphotericin biosynthesis in Streptomyces nodosus: deductions from
RT   analysis of polyketide synthase and late genes.";
RL   Chem. Biol. 8:713-723(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16079135; DOI=10.1074/jbc.M506689200;
RA   Carmody M., Murphy B., Byrne B., Power P., Rai D., Rawlings B.,
RA   Caffrey P.;
RT   "Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl
RT   groups.";
RL   J. Biol. Chem. 280:34420-34426(2005).
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DR   EMBL; AF357202; AAK73504.1; -; Genomic_DNA.
DR   HSSP; Q8RN03; 1UED.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002397; Cyt_P450_B.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19383; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00359; BP450.
PE   4: Predicted;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase.
SQ   SEQUENCE   396 AA;  43135 MW;  E2E4E03B41737289 CRC64;
     MVNPTPPPSL EDAAPSVLRL SPLLRELQMR APVTKIRTPA GDEGWLVTRH AELKQLLHDE
     RLARAHADPA NAPRYVKSPL MDLLIMDDVE AARAAHAELR TLLTPQFSAR RVLNMMPMVE
     GIAEQILNGF AAQEQPADLR GNFSLPYSLT VLCALIGIPL QEQGQLLAVL GEMATLNDAE
     SVARSQAKLF GLLTDLAGRK RAEPGDDVIS RLCETVPEDE RIGPIAASLL FAGLDSVATH
     VDLGVVLFTQ YPDQLKEALA DEKLMRSGVE EILRAAKAGG SGAALPRYAT DDIEIADVTI
     RTGDLVLLDF TLVNFDEAVF DDADLFDIRR SPNEHLTFGH GMWHCIGAPL ARMMLKTAYT
     QLFTRLPGLK LASSVEELQV TSGQLNGGLT ELPVTW
//