ID   Q93TW8_STIAU            Unreviewed;      1840 AA.
AC   Q93TW8;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   19-JAN-2010, entry version 46.
DE   SubName: Full=MxaD;
GN   Name=mxaD;
OS   Stigmatella aurantiaca.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Cystobacteraceae; Stigmatella.
OX   NCBI_TaxID=41;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=21110452; PubMed=11182319; DOI=10.1016/S1074-5521(00)00056-9;
RA   Silakowski B., Nordsiek G., Kunze B., Blocker H., Muller R.;
RT   "Novel features in a combined polyketide synthase/non-ribosomal
RT   peptide synthetase: the myxalamid biosynthetic gene cluster of the
RT   myxobacterium Stigmatella aurantiaca Sga15.";
RL   Chem. Biol. 8:59-69(2001).
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DR   EMBL; AF319998; AAK57188.1; -; Genomic_DNA.
DR   SMR; Q93TW8; 1439-1793.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   InterPro; IPR001227; Ac_transferase_dom.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPlipase.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR002198; DH_sc/Rdtase_SDR.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   InterPro; IPR020842; PKS/FAS_KR.
DR   InterPro; IPR020801; PKS_acyl_transferase.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_reg.
DR   InterPro; IPR020807; PKS_dehydratase.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR006162; PPantetheine_attach_site.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR016038; Thiolase-like_subgr.
DR   Gene3D; G3DSA:3.40.366.10; Ac_transferase_reg; 1.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:3.40.47.10; Thiolase-like_subgr; 2.
DR   PANTHER; PTHR11712; Ketoacyl_synth; 1.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00827; PKS_AT; 1.
DR   SMART; SM00826; PKS_DH; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine; Transferase.
SQ   SEQUENCE   1840 AA;  197910 MW;  C03073FBF0CEBAD9 CRC64;
     MLLALDLHAE SEALKRTRSE PIAIVGTSCR VPGGARTPEA FWRLLHGGVD AITEVPRDRW
     DAEALFDPDP NKQGRTYARW GGFIDGVDRF DAAFFGVSPR EASRMDPQQR MLLEVAWEAL
     ERAGQPPDQL AGSRTGVFLG IIGSDYAQLQ ARLLGDSPDI YHLTGTSLNA AAGRLSYTLG
     LQGPCMSIDT ACSSSLVALH VACQSLRNRE CDLALSAGVN LMLMPDATIA LSSSRGLSPD
     GRCKTFDAAA NGFVRAEGCV VLVLKRLSDA LASGDEILSL IAGSAVNQDG ASSGLMVPNG
     PAQERVIEQA LASGGLKPSQ ISFVEAHGTG TSLGDPIELQ ALARVLGTGR SAETPLFVGS
     VKTNVGHLEA TAGLTGVLKT ALALRNETIP PNLHFKRLNP DIVLDGAPVV VPTEPRSWPR
     AEQPRFAGVS AFGISGTNAH IILQEPPVPA PQAVVPPRGS ELLVLSARSP EALRAVAANH
     ARWFSEHPDG ALREVCATAA LSRSHHDHRL ALAGRTPAEF VEKLEAFSRG EAAPGAATGR
     RTGQARRRVV FVFPGQGSQW VGMGRKLLEE EPSFRAALER CDAAIRACAD FSVLGELAAE
     AGRGRLHEID VIQPVLFAME VALAEMWRAW GIEPSAVVGH SMGEVAAAHV AGTLSLEDAA
     KIICRRSRLL RSVSGQGSML LVDLTMEEAK QALRGFEDRV SVAVSNSVRS TVLSGAPAAI
     EEISNNLKQR DVFCRFVKVD VASHSPQMDP LRSELLAALQ EIAPRAAHVP ICSTVTGGMT
     DGASFSANYW ADNLREPVLF SKAIERLAVE GHDIFIELSP HPILLPAVEQ HLRHLGREGA
     VLPSLRRDED ERGSMLSSLG ALYAMGHEVD LQRQHPVRGR RVALPTYPWQ HERFWVEAPA
     RSRRAQAAGH HPLLGAHVAL AGQEGSHLWQ TELFADSPSY LGDHVVHGEV VLPGTGYLEM
     ALAGAAEALG SGKHALEDVI FQEMMVLPRE EALSVQMSFV SDDDGAKRFR IFSRPADAGE
     GWTLHAEGRI RQGVEAEAFA LEEARARCTE RMDGETHYQL MKERGVDFGP SFRLLKEMWK
     GSGEAVARLE LPSSVASEMA AHQLHPALLD ACFQVINGAG LGERPGETFV PVAVENLRAY
     GRPGRELWGH ARVRSGTSSG PGSVEADVTL LDGEGRVLME ARGLMCRRLD AVRRRSADEI
     DKWMYLVEWQ EEPRGDVAPT PASAPGAWLV LADRQGFGKK LQAVLRERGE QCVLVSQGEE
     SRLVEPGHYV VDLSKTEGFA RILEAEFGSG RPACRGVVHL FSLDAPRPEE GLQALAKARS
     LGAESALHLT QALVASGFRD MPRVWLVTEG VQAVKPAERV AHVEQAPIWG IGRVLSLEHP
     EFRCCSVDLG ALDEAQARVL ADELFSSTLE EQVALRGTAR FVARLSRMER SKAAPAELRA
     DGTYLITGGL GGLGLKLAEW LVARGARHIA LLGRGNGSAE AQQTLEALRA AGAEVRVCKA
     DVAVRADLER VFGELAAGMP PLRGVFHAAA VLDDGVLVNL TSERLRAVME PKIHGAWNLH
     ELTASAPLDF FVLFAAAGSL LGSPGQGNYA AANVFLDALA SYRRGLGLPA LSVDWGSWAG
     VGLAAAAEAR GERIAQRGVD SMQPAQALEA LGRVLESPHA RVVVMRFELR QWREFYLTAA
     QSPFLSRLAR EQANSGESSA NRGAFVETLR AAERPKRAQL LEAHLCEQAG HVLRMSPSRI
     DPQQPLGSLG LDSLMGLEIR NRLEASLGLR LPATLVWRYP TVAALVEHLA EQLQLSITNK
     AEQPQDEAAA LEAEIVNNVK QLSDEEAEAL LAEKLAALAE
//