ID   Q9F837_9ACTO            Unreviewed;       374 AA.
AC   Q9F837;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   19-JAN-2010, entry version 21.
DE   SubName: Full=TDP-3-keto-6-deoxyhexose 3-aminotransaminase;
GN   Name=megDII;
OS   Micromonospora megalomicea subsp. nigra.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Micromonosporineae; Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=136926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL3275;
RX   MEDLINE=20430101; PubMed=10972798;
RX   DOI=10.1046/j.1365-2958.2000.02059.x;
RA   Volchegursky Y., Hu Z., Katz L., McDaniel R.;
RT   "Biosynthesis of the anti-parasitic agent megalomicin: transformation
RT   of erythromycin to megalomicin in Saccharopolyspora erythraea.";
RL   Mol. Microbiol. 37:752-762(2000).
CC   -!- SIMILARITY: Belongs to the degT/dnrJ/eryC1 family.
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DR   EMBL; AF263245; AAG13910.1; -; Genomic_DNA.
DR   HSSP; Q8ZNF3; 1MDO.
DR   SMR; Q9F837; 15-372.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   InterPro; IPR000653; DegT/StrS_aminotransferase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase_major_dom.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_major_sub2.
DR   Gene3D; G3DSA:3.40.640.10; PyrdxlP-dep_Trfase_major_sub1; 1.
DR   Gene3D; G3DSA:3.90.1150.10; PyrdxlP-dep_Trfase_major_sub2; 1.
DR   Pfam; PF01041; DegT_DnrJ_EryC1; 1.
DR   PIRSF; PIRSF000390; PLP_StrS; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate.
SQ   SEQUENCE   374 AA;  41521 MW;  82356AFBC98BD3E1 CRC64;
     MTTYVWSYLL EYERERADIL DAVQKVFASG SLILGQSVEN FETEYARYHG IAHCVGVDNG
     TNAVKLALES VGVGRDDEVV TVSNTAAPTV LAIDEIGARP VFVDVRDEDY LMDTDLVEAA
     VTPRTKAIVP VHLYGQCVDM TALRELADRR GLKLVEDCAQ AHGARRDGRL AGTMSDAAAF
     SFYPTKVLGA YGDGGAVVTN DDETARALRR LRYYGMEEVY YVTRTPGHNS RLDEVQAEIL
     RRKLTRLDAY VAGRRAVAQR YVDGLADLQD SHGLELPVVT DGNEHVFYVY VVRHPRRDEI
     IKRLRDGYDI SLNISYPWPV HTMTGFAHLG VASGSLPVTE RLAGEIFSLP MYPSLPHDLQ
     DRVIEAVREV ITGL
//