ID   Q9L4X0_9ACTO            Unreviewed;       394 AA.
AC   Q9L4X0;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   01-SEP-2009, entry version 36.
DE   SubName: Full=NysL;
GN   Name=nysL;
OS   Streptomyces noursei.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1971;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 11455;
RX   MEDLINE=20334850; PubMed=10873841; DOI=10.1016/S1074-5521(00)00120-4;
RA   Brautaset T., Sekurova O.N., Sletta H., Ellingsen T.E., StrLm A.R.,
RA   Valla S., Zotchev S.B.;
RT   "Biosynthesis of the polyene antifungal antibiotic nystatin in
RT   Streptomyces noursei ATCC 11455: analysis of the gene cluster and
RT   deduction of the biosynthetic pathway.";
RL   Chem. Biol. 7:395-403(2000).
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DR   EMBL; AF263912; AAF71769.1; -; Genomic_DNA.
DR   HSSP; Q00441; 1OXA.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002397; Cyt_P450_B.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19383; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00359; BP450.
PE   4: Predicted;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase.
SQ   SEQUENCE   394 AA;  43118 MW;  DD771AE90142C34F CRC64;
     MSTPTAPPSL KAEVPPVLRL SPLLRELQSR APVCKVRTPA GDEGWLVTRH TELKQLLHDD
     RLARAHADPA NAPRYVHNPF LDLLVVDDFD LARTLHAEMR SLFTPQFSAR RVMDLTPRVE
     ALAEGVLAHF VAQGPPADLH NDFSLPFSLS VLCALIGVPA EEQGKLIAAL TKLGELDDPA
     RVQEGQDELF GLLSGLARRK RITPEDDVIS RLCLKVPSDE RIGPIASGLL FAGLDSVASH
     IDLGTVLFIQ HPDQLAAALA DEKLMRGAVE EILRSAKAGG SVLPRYATAD VPIGDVTIRA
     GDLVLLDFTL VNFDRTVFDE PELFDIRRAP NPHLTFGHGM WHCIGAPLAR VNLRTAYTLL
     FTRLPGLRLV RPVEELRVLS GQLSAGLTEL PVTW
//