ID   Q9L9F6_STRSH            Unreviewed;       527 AA.
AC   Q9L9F6;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   19-JAN-2010, entry version 28.
DE   SubName: Full=NovL;
GN   Name=novL;
OS   Streptomyces sphaeroides (Streptomyces caeruleus).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=195949;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RX   MEDLINE=20233587; PubMed=10770754;
RX   DOI=10.1128/AAC.44.5.1214-1222.2000;
RA   Steffensky M., Muhlenweg A., Wang Z.X., Li S.M., Heide L.;
RT   "Identification of the novobiocin biosynthetic gene cluster of
RT   Streptomyces spheroides NCIB 11891.";
RL   Antimicrob. Agents Chemother. 44:1214-1222(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RX   MEDLINE=20347301; PubMed=10801869; DOI=10.1074/jbc.M003066200;
RA   Steffensky M., Li S.M., Heide L.;
RT   "Cloning, overexpression, and purification of novobiocic acid
RT   synthetase from Streptomyces spheroides NCIMB 11891.";
RL   J. Biol. Chem. 275:21754-21760(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RA   Steffensky M., Muehlenweg A., Wang Z., Li S.M., Heide L.;
RL   Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AF170880; AAF67505.1; -; Genomic_DNA.
DR   HSSP; P08659; 1LCI.
DR   SMR; Q9L9F6; 19-515.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   Pfam; PF00501; AMP-binding; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
SQ   SEQUENCE   527 AA;  56921 MW;  C19F1B702E099E94 CRC64;
     MANKDHAPEH YVTRILAEAT LDGARPVVRW RDTVITGTQL DRSVRRVVTA LREAGVARDH
     AVAVLTQVNS PWMLIVRYAA HLVGASVVYI TGANHGIVTH ELPVATRVRM LREAGASVLV
     FDESNAQLAE TVDETVRDKL VLCGLGHPAS GTVSVDGRPV DDVSVDFTPE APELAMVLYT
     SGTTGQPKGV CRSFGSWNAA ALRGAAYPRP VFLTMTAVSQ TVAMIVDTVL AAGGSVLLRE
     RFDPADFLRD VGEHRVTETF MGVAQLYAIL GHPDARTADL SSLRHVLYLG CPASPERLRE
     AAALLPGVLA QSYGSTEAGR ITVLRAADHE RPELLATVGR AVPGVTIAIR DPETGHDLPV
     GEIGEVVVHG PEVMAGYVAD PEHTARVIRD GWVHTGDFGS VDERGYVRLF GRMREVVKVQ
     DTRVSPTEVE KVLVGCPGVV DACVYGHRGP DLIEELHAAV VLGTEGAPSF DTLRDHVARA
     MTPTHAPIRF VRWRRFPINN TGKVNRLRVR EVSAEARGDS PDVLVDR
//