ID   Q9L9F8_STRSH            Unreviewed;       262 AA.
AC   Q9L9F8;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   19-JAN-2010, entry version 39.
DE   SubName: Full=NovJ;
GN   Name=novJ;
OS   Streptomyces sphaeroides (Streptomyces caeruleus).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=195949;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RX   MEDLINE=20233587; PubMed=10770754;
RX   DOI=10.1128/AAC.44.5.1214-1222.2000;
RA   Steffensky M., Muhlenweg A., Wang Z.X., Li S.M., Heide L.;
RT   "Identification of the novobiocin biosynthetic gene cluster of
RT   Streptomyces spheroides NCIB 11891.";
RL   Antimicrob. Agents Chemother. 44:1214-1222(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RA   Steffensky M., Muehlenweg A., Wang Z., Li S.M., Heide L.;
RL   Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family.
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DR   EMBL; AF170880; AAF67503.1; -; Genomic_DNA.
DR   HSSP; P25716; 1Q7B.
DR   SMR; Q9L9F8; 15-261.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002198; DH_sc/Rdtase_SDR.
DR   InterPro; IPR002347; Glc/ribitol_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR19410; ADH_short_C2; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
SQ   SEQUENCE   262 AA;  26850 MW;  FB86B3336F66FDBD CRC64;
     MTSPADATTE VAVSQESVAM VTGAGRGIGA ATAERLAAEG MAVIVVDRTE QDTRATVAAI
     RTAGGRARGI GCDVAVAQAV TAAVATAVEE FGRIDVLVNC AGINRDRLLL TMGDQEWDTV
     LDVNLGGTMR CSFAVGRHMR RQGHGRIINF SSVAARGNAG QTNYATAKGA IAGFTRTLAA
     ELGPHGVTVN AIAPGFVATP MVDELAERLG GDRDSVMSEA AKSSAVGRIG TPEEIAATVV
     FVARPESGYL TGETVHVDGG RP
//