ID   Q9L9G0_STRSH            Unreviewed;       600 AA.
AC   Q9L9G0;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   19-JAN-2010, entry version 48.
DE   SubName: Full=NovH;
GN   Name=novH;
OS   Streptomyces sphaeroides (Streptomyces caeruleus).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=195949;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RX   MEDLINE=20233587; PubMed=10770754;
RX   DOI=10.1128/AAC.44.5.1214-1222.2000;
RA   Steffensky M., Muhlenweg A., Wang Z.X., Li S.M., Heide L.;
RT   "Identification of the novobiocin biosynthetic gene cluster of
RT   Streptomyces spheroides NCIB 11891.";
RL   Antimicrob. Agents Chemother. 44:1214-1222(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIB 11891;
RA   Steffensky M., Muehlenweg A., Wang Z., Li S.M., Heide L.;
RL   Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AF170880; AAF67501.1; -; Genomic_DNA.
DR   HSSP; P14687; 1AMU.
DR   SMR; Q9L9G0; 20-517, 526-595.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR020459; AMP-binding.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   InterPro; IPR006162; PPantetheine_attach_site.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   PRINTS; PR00154; AMPBINDING.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine.
SQ   SEQUENCE   600 AA;  63532 MW;  851E2CEAF4E05538 CRC64;
     MFNTRANKAS DQSPTIPTES ATLAELWERT VRSRPSSPAI VTNGETLSYD EVNARANRLA
     RLLLDEGAGP GRLVALALPR SSHLVISVLA VAKAGAVFLP LDVNHPRERL SYQLADARPA
     LLCTVRSAAA RLPDGIEMPR VLLDSPERTA VLDALPDTDL TDDERGGPLA ATDLAYVIYT
     SGSTGRPKGV ALTGAGLPAL AAAKVAAMRV TGDSRVLQFA SPGFDAYLTE LLAAFTAGAT
     LVVPGTDTLA GDPLRRALRD GRVSHAVLRP RRSATMSPDA VPDLRVLVVA GEACPAGLVE
     RWAPGRLLIN AYGPTECTVC ATMTGPLTPT DEVTIGRPIP GVSVYILDAE RRPAAPGEIG
     ELYLSGAGLA QGYLNSPDLT AQMFVPNPFA ADGERMYRTG DLASRRADGD ILFHGRIDDQ
     VELRGFRVEL GEVESVLSQH PDVAQAVAAL WTDPAEGPQL VTYVVPAPGT TPSAGELREH
     AGRFLPDFMV PSAFTTIDAV PLTPGGKTDR AGLPDPVKAT QPAGLGPRTP AEKVLCDIFR
     DLFDLVEIDV RSNFFEMGGN SILAVDLIQR AQEAGLTLMP RTVIDHPTIE QLAAIATLEE
//