ID   Q9RNB5_MICAE            Unreviewed;      2631 AA.
AC   Q9RNB5;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   19-JAN-2010, entry version 51.
DE   SubName: Full=McyG;
GN   Name=mcyG;
OS   Microcystis aeruginosa PCC 7806.
OC   Bacteria; Cyanobacteria; Chroococcales; Microcystis.
OX   NCBI_TaxID=267872;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC7806;
RX   MEDLINE=20491409; PubMed=11033079; DOI=10.1016/S1074-5521(00)00021-1;
RA   Tillett D., Dittmann E., Erhard M., von Dohren H., Borner T.,
RA   Neilan B.A.;
RT   "Structural organization of microcystin biosynthesis in Microcystis
RT   aeruginosa PCC7806: an integrated peptide-polyketide synthetase
RT   system.";
RL   Chem. Biol. 7:753-764(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC7806;
RX   PubMed=15528494; DOI=10.1128/AEM.70.11.6370-6378.2004;
RA   Pearson L.A., Hisbergues M., Borner T., Dittmann E., Neilan B.A.;
RT   "Inactivation of an ABC transporter gene, mcyH, results in loss of
RT   microcystin production in the cyanobacterium Microcystis aeruginosa
RT   PCC 7806.";
RL   Appl. Environ. Microbiol. 70:6370-6378(2004).
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DR   EMBL; AF183408; AAF00957.1; -; Genomic_DNA.
DR   HSSP; O30409; 1DNY.
DR   GO; GO:0000036; F:acyl carrier activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   InterPro; IPR001227; Ac_transferase_dom.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPlipase.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR006163; Phsphopanteth_bd.
DR   InterPro; IPR020842; PKS/FAS_KR.
DR   InterPro; IPR020801; PKS_acyl_transferase.
DR   InterPro; IPR013968; PKS_KR.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR016038; Thiolase-like_subgr.
DR   Gene3D; G3DSA:3.40.366.10; Ac_transferase_reg; 1.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:3.40.47.10; Thiolase-like_subgr; 2.
DR   PANTHER; PTHR11712; Ketoacyl_synth; 1.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF08659; KR; 1.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   Pfam; PF00550; PP-binding; 2.
DR   SMART; SM00827; PKS_AT; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SMART; SM00823; PKS_PP; 2.
DR   PROSITE; PS50075; ACP_DOMAIN; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE   4: Predicted;
KW   Transferase.
SQ   SEQUENCE   2631 AA;  294159 MW;  6A71AE21AFDAA657 CRC64;
     MSKHSISLGG QLEDNWRTLS EVLETATKHN NHGITYIRND ATEYFQSYQD LYQDALVILN
     GLEQKGIKLG HKVILQIAKN QDFIPALWAC FLGGIIPVPL TVAPSYDLEN SAVKKLENVW
     KILDNPLILS DSELITEIEK LGTYSHLEGW QVISVNELRK APSKIEQLPI LDPQDAALLL
     FTSGSTGMPK GVILTHHNIL SMTAGTVVMN HFTQQEVTLN WMPLDHVGAI VFLGIMAVDL
     ACDQIHVPME LVLRQPLQWL ELIQKHQVSI SWSPNFAFSL INQQAEELKH VSYNLSSMKF
     LVNAGEQVSV KTIRLFLEIL EKHQLQERAI KPAFGMTESC SGITWSAGLS KNELTEENSF
     VSLGKPIPGA TIRIVDQENN PLPEREIGRL QIQGNSVTKG YYNNNELNQE VFQEGWFTTG
     DLGYLSKGEL FITGREKQEI IINGVNYFAH ELETTIEELE GVKVSYTAAF AVFDQSRETD
     LLIITFSPES EQFEQGIKVV RKIRSHVTQK FGIAPAYVIP LERNLVPKTS IGKVQKSKLK
     KDFEQGLFST RIQEIDQYLA KERQKNQTLP QSENERQIAA VWSEVLQLTS VGLEDNFFEL
     GGHSIHLIRV QNELEKLFNR QLSLAEMFKN PTVATLARFL SEESNTNQVI AQKSRQRAEN
     RSRRHNETHD IAIIGMTGQF PGAKNLTTFW ENLKNGIETI SFFSEEELQE SGVSSELFNQ
     PNYVRARPIL EQVEYFDSEF FGYTDREAEL LDPQQRLLLE CSWECLENAG YNPNTYQGSI
     GIFAGASMNT YLINNCYPNR GKLDSNDELQ PFTLDSMGGF QTMVANDKDY LTTRISYKLN
     LHGPSVNVQT ACSTGLVVVH LACQSLISGE SDMALAGAAS INSPQKIGYL YQEGLIMSPD
     GHCRAFDAEA KGTIFGSGVG VIMLKRLSDA LADHDHIYAV IKGSAINNDG GQKLGFTAPG
     GEGQIAAATE ALAFAGVDAN TISFVEAHGT GTPLGDPIEV DALAKVYQGA NEGECALGSV
     KTNIGHMQIA SGIAGLIKAT LALKYRVIPP TLHFQNPNPQ INFSQTPFYI NNEAISWTTK
     QDKSEKLPRR AGVNSLGIGG VNAHVILEEA PPIIPQDNQS QRPYHLLTLS ARTELALTEL
     VSRYIDFLES QPEKDLSDVV FTANTGRVHF SNRLALTGYK NSDFIEQLRQ FKQLDYESTI
     YGIVDEKRPS KIAFLFTGQG SQYVGMAHQL YQTQPTFRKT LDAGEKYHQK LTGKSLLNVV
     FADTDDSLNQ TAYTQPALFL IEVALAQLWH SWGIQPAAIL GHSLGEYSAA CFAGVFDLES
     GLKLVSHRGN LMGQLPQNQG EMAAIFLDKN SVVEHCQSQG IKIAIAAINA EQHTVISGEK
     NVIQKLCNHF TNAGVKVRQL KVAHAFHSPL VEPMVAEFKT ILQEISFSQP QISLVSNLTG
     EIADDSIMTP EYWLQHLLNT VQFHQGALFL QSLGCDTFIE IGPQPILSGI IQSSLSSSEP
     LTLPSLRSGF SDWQVLLESL GKLYVRGAKI DWFSFDQDYH PRRCALPTYP FQKRQHWISL
     KTPSATVPRE SNLVKMLSEK DKTTLMQTLL ETGHYSEDEK PTISAIVQQL IKLYYQEKED
     FDFAKLLYQV AWLPCDLANG KLENLTSLKT DLEVYLEPQL QSSELMGVSL AFSEMEKLAA
     DFVVKALKDL ELFQMNTFLD PDQSFIQAGL KQEYKSFWNY VLEILAKVGI LEKQNTRWKI
     VKEPEQSNPD LAVEDLINHY PNAQIELNLF RQVATNLAAI ITGKISPLSI LFSQDGQGGA
     SEFYKNTSSA KILNLGISKT VELLLSSYPP SASLRILEIG AGTGATTQQV LKACNSRQIT
     YTFTDVSPFF LEKARDNLAE FSELEYKVLD IEKDPKLQGF CCHSYDLIIA ANVLHSTANL
     QEETLPHIQS LLRPGGHLLL LELTQQSSWI DLIFGVTQGW WRFSDYHLRP NHPIITASTW
     ESMLLKSGFS QVEFVSPDQK IGTALFQQSI ILAQSSEISS NTAKNWLIFT DVEPQQNTFA
     LGIQEQLLKK CDSCRIIYQG EKNTQISSSE SCLNANQLQQ LEEWFASNPS PDRIIYLLNS
     DGKDQPESIL LNRCNYLLNL LKAIQKIPNP PQLFLVTQGA QPFELEQPSF GFQSPLWAMG
     RVIALENPQL WGGMLDLDPD VDINQNITAL LLGLTHAHDE DHLVFRKGQG YVARLLPLKS
     LETKTIKIQP EATYLITGGI GHLGLELAEH LVNLGAKHLI LTTRRSLPVR FLWDSAAELA
     QISQKIRKLE EKGASIAVTS ADVGNFEAMQ AIFTQIEETA YPLRGIFHLA GISGRQAQLK
     DCTLQDLEAV FQAKVKGSWN LHQLSLGSQL DYFVLFSSAG AIWGAKEQGL YDTVSHWLDA
     LAHFRHLQGL PATTLNWALL AGHGIVSQDY EDWLKQIGIR EIAPDMALRV MDAIMASNQT
     QVLIADVDWV RFKNIYQFKG EKPLLKNLGL SEIPINSVQE SDSVLHLLEE MPFGERREYL
     LEYVSKQVRM ILGIKSMPDT EQGLIEMGID SLSSIELKNR LEKRLEVLLP TSLVFDFPNI
     RRLVDYLFDR IFGEKVQKTA EKMINFTEVQ QEISEDLILQ ELTDLEAFLG D
//