ID   Q9RNB7_MICAE            Unreviewed;       337 AA.
AC   Q9RNB7;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   19-JAN-2010, entry version 45.
DE   SubName: Full=McyI;
GN   Name=mcyI; ORFNames=IPF_368;
OS   Microcystis aeruginosa PCC 7806.
OC   Bacteria; Cyanobacteria; Chroococcales; Microcystis.
OX   NCBI_TaxID=267872;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC7806;
RX   MEDLINE=20491409; PubMed=11033079; DOI=10.1016/S1074-5521(00)00021-1;
RA   Tillett D., Dittmann E., Erhard M., von Dohren H., Borner T.,
RA   Neilan B.A.;
RT   "Structural organization of microcystin biosynthesis in Microcystis
RT   aeruginosa PCC7806: an integrated peptide-polyketide synthetase
RT   system.";
RL   Chem. Biol. 7:753-764(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC7806;
RX   PubMed=15528494; DOI=10.1128/AEM.70.11.6370-6378.2004;
RA   Pearson L.A., Hisbergues M., Borner T., Dittmann E., Neilan B.A.;
RT   "Inactivation of an ABC transporter gene, mcyH, results in loss of
RT   microcystin production in the cyanobacterium Microcystis aeruginosa
RT   PCC 7806.";
RL   Appl. Environ. Microbiol. 70:6370-6378(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7806;
RA   Frangeul L.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family.
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DR   EMBL; AF183408; AAF00955.1; -; Genomic_DNA.
DR   EMBL; AM778952; CAO90233.1; -; Genomic_DNA.
DR   HSSP; P08328; 1PSD.
DR   SMR; Q9RNB7; 17-322.
DR   BRENDA; 1.1.99.6; 258484.
DR   GO; GO:0051287; F:NAD or NADH binding; IEA:InterPro.
DR   GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006564; P:L-serine biosynthetic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR006140; D-isomer_2_OHA_DH_NAD-bd.
DR   InterPro; IPR015508; D3PG_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR10996:SF20; D3PG_Deh; 1.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   337 AA;  36713 MW;  C20E9893C2B59BE4 CRC64;
     MTTTSPKTLT MDIQKPRVLL IGKMYDEAGQ KLLEESTNIE ILSNPTPEEI NEAIQEVSGV
     FVRYPNNLEA SSIRLAKHLK VISTSGFGTD SIDIMAATEQ GVIVVNNPGM STTAVAEHTL
     SMILALAKKL PFLDHCVKKG NYLIRNQMQP IQLENKTLGI VGLGRIGTLV AHKCNLALGM
     RVLAYDPYVP ASKAETVGAT LLKDLDVLLA ESDFVSLHTE LTSETREMFN ISVFKKMKPT
     AFLINTSRGK VVCEKDLGIA LNQKLISGCA LDVFEPEPPA LDNPLYNFEN VILSPHLAGV
     TPEASLAAAV SAANQILQVL RGEKPPYMIN PEAWNLF
//