ID   Q9RR32_STRAT            Unreviewed;       328 AA.
AC   Q9RR32;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   19-JAN-2010, entry version 34.
DE   SubName: Full=DTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase;
DE   SubName: Full=Putative 3-ketoreductase;
GN   Name=oleW;
OS   Streptomyces antibioticus.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1890;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 11891;
RX   MEDLINE=20233594; PubMed=10770761;
RX   DOI=10.1128/AAC.44.5.1266-1275.2000;
RA   Aguirrezabalaga I., Olano C., Allende N., Rodriguez L., Brana A.F.,
RA   Mendez C., Salas J.A.;
RT   "Identification and expression of genes involved in biosynthesis of L-
RT   oleandrose and its intermediate L-olivose in the oleandomycin producer
RT   Streptomyces antibioticus.";
RL   Antimicrob. Agents Chemother. 44:1266-1275(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 11891;
RA   Quiros L.M., Aguirrezabalaga I., Olano C., Mendez C., Salas J.A.;
RL   Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Tu99;
RA   Draeger G., Park S.H., Floss H.G.;
RT   "Mechanism of the 2-deoxygenation step in the biosynthesis of the
RT   deoxyhexose moieties of the antibiotics granaticin and oleandomycin.";
RL   J. Am. Chem. Soc. 121:2611-2612(1999).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Tu99;
RA   Park S.H., Sohng J.K., August P.R., Niggemann J., Floss H.G.;
RT   "A cluster of genes from Streptomyces antibioticus involved in the
RT   biosynthesis of the deoxysugar moieties of oleandomycin.";
RL   Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AF055579; AAD55450.1; -; Genomic_DNA.
DR   EMBL; AF237894; AAF59931.1; -; Genomic_DNA.
DR   PIR; T51102; T51102.
DR   SMR; Q9RR32; 6-327.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR000683; Oxidoreductase_N.
DR   InterPro; IPR004104; OxRdtase_C.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
PE   4: Predicted;
SQ   SEQUENCE   328 AA;  35835 MW;  271B218F26C11A31 CRC64;
     MPSPRLRFGV LGAADIALRR TVPALLAHPD VTVVAVSSRD TARAARFAAA FGCEAVPGHQ
     ALLDRDDIDA LYVPLPVMVH TPWVEAALLR GRHVLVEKPL TATRSGAEDL IALARSRGLV
     LMENFTSLHH AQHGTVTDLL RDGTIGELRS LSAAFTIPPK PEGDIRYQPD VGGGALLDIG
     IYPLRAALHF LGPDLHAAGA VLRRERRRNV VVSGHVLLTT PHGVVAELAF GMEHAYRSEY
     TLFGTAGRLR LDRAFTPPET HRPRVEIHRQ DALDIVDLPP DAQFANLVRD FVLAVREGPG
     RLTQHHADAV RQADLVERVM AVARVRWC
//