ID   Q9S4D6_STRFR            Unreviewed;       436 AA.
AC   Q9S4D6;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   19-JAN-2010, entry version 41.
DE   SubName: Full=Cytochrome P450 TylHI;
GN   Name=tylHI;
OS   Streptomyces fradiae.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1906;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=T59235;
RA   Bate N., Cundliffe E.;
RT   "The mycinose-biosynthetic genes of Streptomyces fradiae, producer of
RT   tylosin.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
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DR   EMBL; AF147703; AAD41818.1; -; Genomic_DNA.
DR   HSSP; Q8RN03; 1UED.
DR   SMR; Q9S4D6; 50-436.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002397; Cyt_P450_B.
DR   InterPro; IPR017973; Cyt_P450_C.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   PANTHER; PTHR19383; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 2.
DR   PRINTS; PR00359; BP450.
DR   PRINTS; PR00385; P450.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase.
SQ   SEQUENCE   436 AA;  47384 MW;  F035BE1BFC324764 CRC64;
     MAWAPDTVFS LRPQRVVSSS GDARPSQKGI LLPAARANDT DEAAGRRSIA WPVARTCPFS
     PPEQYAALRA EEPIARAELW DGAPVWLISR QDHVRALLAD PRVSIHPAKL PRLSPSDGEA
     EASRSLLTLD PPDHGALRGH FIPEFGLRRV RELRPSVEQI VTGLLDDLTA RGDEADLLAD
     FALPMATQVI CRLLDIPYED RDYFQERTEQ ATRPAAGEEA LEALLELRDY LDRLISGKTG
     RESGDGMLGS MVAQARGGGL SHADVLDNAV LLLAAGHETT ASMVTMSVLV LLQHPTAWRE
     LTVNPGLLPG AVDELLRYLS IADGLRRSAT ADIEIDGHTI RAGDGLVFLL AAANRDEAVF
     SEPEAFDIHR SARRHVAFGY GPHQCLGQNL ARMELEVALG AVLERLPALR PTTDVAGLRL
     KSDSAVFGVY ELPVAW
//