KEGG   PATHWAY: vvi04626Help
Entry
vvi04626                    Pathway                                

Name
Plant-pathogen interaction - Vitis vinifera (wine grape)
Description
Plants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pathogens by cell-surface pattern-recognition receptors (PRRs) and is referred to as PAMP-triggered immunity (PTI). Activation of FLS2 and EFR triggers MAPK signaling pathway that activates defense genes for antimictobial compounds. The increase in the cytosolic Ca2+ concentration is also a regulator for production of reactive oxygen species and localized programmed cell death/hypersensitive response. The secondary response is called effector-triggered immunity (ETI). Pathogens can acquire the ability to suppress PTI by directly injecting effector proteins into the plant cell through secretion systems. In addition, pathogens can manipulate plant hormone signaling pathways to evade host immune responses using coronatine toxin. Some plants possess specific intracellular surveillance proteins (R proteins) to monitor the presence of pathogen virulence proteins. This ETI occurs with localized programmed cell death to arrest pathogen growth, resulting in cultivar-specific disease resistance.
Class
Organismal Systems; Environmental adaptation
BRITE hierarchy
Pathway map
Plant-pathogen interaction
vvi04626

All organismsOrtholog table
Organism
Vitis vinifera (wine grape) [GN:vvi]
Gene
calcium-dependent protein kinase 3 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 24 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 4 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 10 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 20 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 13 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 34-like [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 32 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase SK5 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 29 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 8 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
calcium-dependent protein kinase 28 [KO:K13412] [EC:2.7.11.1]
calcium and calcium/calmodulin-dependent serine/threonine-protein kinase [KO:K13412] [EC:2.7.11.1]
respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.11.1.- 1.6.3.-]
respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.11.1.- 1.6.3.-]
respiratory burst oxidase homolog protein D-like [KO:K13447] [EC:1.11.1.- 1.6.3.-]
respiratory burst oxidase homolog protein C-like [KO:K13447] [EC:1.11.1.- 1.6.3.-]
respiratory burst oxidase homolog protein D-like [KO:K13447] [EC:1.11.1.- 1.6.3.-]
respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.11.1.- 1.6.3.-]
probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
putative cyclic nucleotide-gated ion channel 15 [KO:K05391]
probable cyclic nucleotide-gated ion channel 14 [KO:K05391]
putative cyclic nucleotide-gated ion channel 15 [KO:K05391]
putative cyclic nucleotide-gated ion channel 8 [KO:K05391]
cyclic nucleotide gated channel-like [KO:K05391]
probable cyclic nucleotide-gated ion channel 17 [KO:K05391]
cyclic nucleotide-gated ion channel 1-like [KO:K05391]
cyclic nucleotide-gated ion channel 1 [KO:K05391]
cyclic nucleotide-gated ion channel 1 [KO:K05391]
cyclic nucleotide-gated ion channel 2 [KO:K05391]
putative cyclic nucleotide-gated ion channel 18 [KO:K05391]
probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
putative cyclic nucleotide-gated ion channel 18 [KO:K05391]
probable calcium-binding protein CML30 [KO:K02183]
calmodulin [KO:K02183]
calmodulin-7 [KO:K02183]
calmodulin-like [KO:K02183]
calmodulin-4 [KO:K02183]
probable calcium-binding protein CML45 [KO:K02183]
putative calcium-binding protein CML23 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
calcium-binding allergen Ole e 8-like [KO:K13448]
probable calcium-binding protein CML41 [KO:K13448]
calcium-binding allergen Ole e 8-like [KO:K13448]
probable calcium-binding protein CML16 [KO:K13448]
EF-hand calcium-binding protein [KO:K13448]
probable calcium-binding protein CML35 [KO:K13448]
calmodulin-like protein 5 [KO:K13448]
probable calcium-binding protein CML18 [KO:K13448]
probable calcium-binding protein CML20 [KO:K13448]
calmodulin-like protein 11 [KO:K13448]
probable calcium-binding protein CML21 [KO:K13448]
putative calcium-binding protein CML19 [KO:K13448]
probable calcium-binding protein CML48 [KO:K13448]
polcalcin Che a 3 [KO:K13448]
probable calcium-binding protein CML15 [KO:K13448]
probable calcium-binding protein CML22 [KO:K13448]
probable calcium-binding protein CML44 [KO:K13448]
calcium binding [KO:K13448]
serine/threonine kinase-like [KO:K13448]
calmodulin-like protein 3 [KO:K13448]
putative calcium-binding protein CML19 [KO:K13448]
caltractin [KO:K13448]
probable calcium-binding protein CML18 [KO:K13448]
putative calcium-binding protein CML23 [KO:K13448]
probable calcium-binding protein CML41 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
putative calcium-binding protein CML19 [KO:K13448]
calmodulin-like protein 1 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
probable calcium-binding protein CML31 [KO:K13448]
calmodulin-like protein 3 [KO:K13448]
calmodulin-like protein 3 [KO:K13448]
putative nitric oxide synthase [KO:K13427] [EC:1.14.13.39]
FLS2; LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
probable LRR receptor-like serine/threonine-protein kinase At3g47570 [KO:K13420] [EC:2.7.11.1]
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 [KO:K13416] [EC:2.7.11.1 2.7.10.1]
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.11.1 2.7.10.1]
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.11.1 2.7.10.1]
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 [KO:K13416] [EC:2.7.11.1 2.7.10.1]
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.11.1 2.7.10.1]
mitogen-activated protein kinase kinase kinase 1-like [KO:K13414] [EC:2.7.11.25]
mitogen-activated protein kinase kinase kinase 1-like [KO:K13414] [EC:2.7.11.25]
mitogen-activated protein kinase kinase kinase 1-like [KO:K13414] [EC:2.7.11.25]
mitogen-activated protein kinase kinase 6 [KO:K04368] [EC:2.7.12.2]
mitogen-activated protein kinase kinase 5 [KO:K13413] [EC:2.7.12.2]
probable WRKY transcription factor 33 [KO:K13424]
WRKY transcription factor 22 [KO:K13425]
WRKY transcription factor 22 [KO:K13425]
glycerol kinase [KO:K00864] [EC:2.7.1.30]
glycerol kinase-like [KO:K00864] [EC:2.7.1.30]
PR1; pathogenesis-related protein [KO:K13449]
basic form of pathogenesis-related protein 1 [KO:K13449]
PR-1; pathogenesis-related protein 1 [KO:K13449]
basic form of pathogenesis-related protein 1 [KO:K13449]
basic form of pathogenesis-related protein 1 [KO:K13449]
pathogenesis-related leaf protein 4 [KO:K13449]
basic form of pathogenesis-related protein 1 [KO:K13449]
basic form of pathogenesis-related protein 1-like [KO:K13449]
pathogenesis-related leaf protein 6 [KO:K13449]
pathogenesis-related leaf protein 6 [KO:K13449]
basic form of pathogenesis-related protein 1-like [KO:K13449]
pathogenesis-related protein 1-like [KO:K13449]
pathogenesis-related genes transcriptional activator PTI6 [KO:K13434]
PTI1-like tyrosine-protein kinase 3 [KO:K13436] [EC:2.7.11.1]
pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
RPM1-interacting protein 4 [KO:K13456]
RPM1-interacting protein 4 [KO:K13456]
RPM1-interacting protein 4-like [KO:K13456]
RPM1-interacting protein 4-like [KO:K13456]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1 [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
uncharacterized aarF domain-containing protein kinase At1g79600, chloroplastic-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1 [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
probable disease resistance RPP8-like protein 4 [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
probable disease resistance protein RF9 [KO:K13457]
putative disease resistance protein At1g50180 [KO:K13457]
putative disease resistance protein At1g50180 [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
disease susceptibility protein LOV1-like [KO:K13457]
putative disease resistance protein At1g50180 [KO:K13457]
disease resistance protein RPP13-like [KO:K13457]
disease resistance protein RPM1-like [KO:K13457]
putative disease resistance protein At1g50180 [KO:K13457]
cysteine and histidine-rich domain-containing protein RAR1 [KO:K13458]
protein SGT1 homolog [KO:K12795]
protein SGT1 homolog [KO:K12795]
endoplasmin homolog [KO:K09487]
heat shock protein 83 [KO:K09487]
heat shock protein 90-1 [KO:K09487]
heat shock protein 83 [KO:K04079]
heat shock protein 83-like [KO:K04079]
heat shock cognate protein 80-like [KO:K04079]
heat shock cognate protein 80 [KO:K04079]
heat shock cognate protein 80-like [KO:K04079]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g61310 [KO:K13459]
probable disease resistance protein At1g61300 [KO:K13459]
probable disease resistance protein At1g61300 [KO:K13459]
probable disease resistance protein At1g61300 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At1g52660 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
disease resistance protein RPS5-like [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g61300 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At1g61300 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
disease resistance protein RFL1-like [KO:K13459]
disease resistance protein RPS2-like [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
disease resistance protein At4g27190 [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At4g27220 [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At1g12280-like [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020-like [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At5g63020 [KO:K13459]
probable disease resistance protein At4g14610 [KO:K13459]
putative disease resistance protein At4g10780 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
probable disease resistance protein At1g12280 [KO:K13459]
disease resistance protein At4g27190-like [KO:K13459]
disease resistance protein RPS2 [KO:K13459]
serine/threonine-protein kinase PBS1 [KO:K13430] [EC:2.7.11.1]
serine/threonine-protein kinase CDL1 [KO:K13430] [EC:2.7.11.1]
EDS1; enhanced disease susceptibility 1 [KO:K18875]
lipase-like PAD4 [KO:K18875]
lipase-like PAD4 [KO:K18875]
lipase-like PAD4 [KO:K18875]
uncharacterized LOC100260427 [KO:K18875]
lipase-like PAD4 [KO:K18875]
WRKY transcription factor 1-like [KO:K18834]
probable WRKY transcription factor 20 [KO:K18835]
probable WRKY transcription factor 2 [KO:K18835]
chitin elicitor receptor kinase 1-like [KO:K13429]
chitin elicitor receptor kinase 1-like [KO:K13429]
chitin elicitor receptor kinase 1-like [KO:K13429]
mitogen-activated protein kinase homolog MMK1 [KO:K14512] [EC:2.7.11.24]
mitogen-activated protein kinase 3 [KO:K20536] [EC:2.7.11.24]
mitogen-activated protein kinase homolog MMK2 [KO:K20600] [EC:2.7.11.24]
Compound
C00027  
Hydrogen peroxide
C00076  
Calcium cation
C00533  
Nitric oxide
C00704  
O2.-
C16844  
Hydroxyl radical
Reference
  Authors
Zipfel C
  Title
Pattern-recognition receptors in plant innate immunity.
  Journal
Curr Opin Immunol 20:10-6 (2008)
Reference
  Authors
Chinchilla D, Shan L, He P, de Vries S, Kemmerling B
  Title
One for all: the receptor-associated kinase BAK1.
  Journal
Trends Plant Sci 14:535-41 (2009)
Reference
  Authors
Boller T, He SY
  Title
Innate immunity in plants: an arms race between pattern recognition receptors in  plants and effectors in microbial pathogens.
  Journal
Science 324:742-4 (2009)
Reference
  Authors
Ma W, Smigel A, Verma R, Berkowitz GA
  Title
Cyclic nucleotide gated channels and related signaling components in plant innate immunity.
  Journal
Plant Signal Behav 4:277-82 (2009)
Reference
  Authors
Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
  Title
MAP kinase signalling cascade in Arabidopsis innate immunity.
  Journal
Nature 415:977-83 (2002)
Reference
  Authors
Zipfel C, Felix G
  Title
Plants and animals: a different taste for microbes?
  Journal
Curr Opin Plant Biol 8:353-60 (2005)
Reference
  Authors
He P, Shan L, Sheen J
  Title
Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.
  Journal
Cell Microbiol 9:1385-96 (2007)
Reference
  Authors
de Wit PJ
  Title
How plants recognize pathogens and defend themselves.
  Journal
Cell Mol Life Sci 64:2726-32 (2007)
Reference
  Authors
Chisholm ST, Coaker G, Day B, Staskawicz BJ
  Title
Host-microbe interactions: shaping the evolution of the plant immune response.
  Journal
Cell 124:803-14 (2006)
Reference
  Authors
McHale L, Tan X, Koehl P, Michelmore RW
  Title
Plant NBS-LRR proteins: adaptable guards.
  Journal
Genome Biol 7:212 (2006)
Reference
  Authors
Dangl JL, Jones JD
  Title
Plant pathogens and integrated defence responses to infection.
  Journal
Nature 411:826-33 (2001)
Reference
  Authors
Jones JD, Dangl JL
  Title
The plant immune system.
  Journal
Nature 444:323-9 (2006)
Reference
  Authors
da Cunha L, McFall AJ, Mackey D
  Title
Innate immunity in plants: a continuum of layered defenses.
  Journal
Microbes Infect 8:1372-81 (2006)
Reference
  Authors
Mudgett MB
  Title
New insights to the function of phytopathogenic bacterial type III effectors in plants.
  Journal
Annu Rev Plant Biol 56:509-31 (2005)
Reference
  Authors
Ma W, Berkowitz GA
  Title
The grateful dead: calcium and cell death in plant innate immunity.
  Journal
Cell Microbiol 9:2571-85 (2007)
Reference
  Authors
Schulze-Lefert P
  Title
Plant immunity: the origami of receptor activation.
  Journal
Curr Biol 14:R22-4 (2004)
Reference
PMID:9868361
  Authors
Van der Biezen EA, Jones JD
  Title
Plant disease-resistance proteins and the gene-for-gene concept.
  Journal
Trends Biochem Sci 23:454-6 (1998)
Reference
  Authors
Abramovitch RB, Anderson JC, Martin GB
  Title
Bacterial elicitation and evasion of plant innate immunity.
  Journal
Nat Rev Mol Cell Biol 7:601-11 (2006)
KO pathway
 

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