KEGG   Vitis vinifera (wine grape): 100255872Help
Entry
100255872         CDS       T01084                                 

Definition
putative bifunctional dihydrofolate reductase-thymidylate synthase
Orthology
K13998  
dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
vvi  Vitis vinifera (wine grape)
Pathway
Pyrimidine metabolism
One carbon pool by folate
Folate biosynthesis
Metabolic pathways
Module
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:vvi00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    100255872
  Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100255872
   00670 One carbon pool by folate
    100255872
Enzymes [BR:vvi01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100255872
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     100255872
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
18
AA seq 570 aa AA seqDB search
MSMLYCAQGSQLFARPGSASALSRLFTVLNVIAKRRVQTSYSVLSGDSAMSYPNGDARVH
PVPQRTYQVVVAATHKMGIGKDGKLPWNLPSDLKFFKELTMTTSDPGKKNAVVMGRKTWE
SIPLNYRPLPGRLNVVLTRSGSFDNATVENVVICGSMPSALKLLAESPYCLSIDKVFVIG
GGQILREALNAPGCDAIHITKIETSIECDTFIPTIDTSVFHPWYSSVPLLENNILYSFVT
YVRVRSSALESFALSSGVNFNGGSVPNKLKIQGFTFLPKMIFERHDEFMYLRQLKEIISS
GAHKADKTGTGTVSKFGCQMRFNLRLSFPLLTTKRVFWRGVVEELLWFISGSTNAKVLQK
KDIHIWDGNASREYLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYMGKGFDQLLD
VIDKIKNKPDDRRIILSSWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGV
PFNIASYALLTCMIAHVCGILPGDFILIIGDAHIYKTHIRPLEEQLQKLPKPFPILKINP
QKKDIESFVAADFELIGYNPHQKIEMKMSV
NT seq 1713 nt NT seq  +upstreamnt  +downstreamnt
atgtcgatgctatattgtgctcaaggatcacaactttttgcaaggcctggttctgcatcg
gctttgtcacgattgtttacagttctcaatgtgattgctaagcgcagggtgcaaacaagc
tattcagttttgtctggtgactctgccatgagctatcctaacggtgatgcaagagtgcat
cctgttccccaaaggacttaccaagttgtggtggctgcaacacataagatgggcattggg
aaggatgggaaattaccatggaatttgccctctgacctcaaatttttcaaggagcttaca
atgactacatcagatcctgggaaaaagaatgcagtagtaatgggcaggaaaacatgggaa
agtatccccctcaactatcgacctttacctggtcgccttaatgtggtgctcactcggtct
gggagttttgataatgcaactgtagagaatgttgtcatatgtggaagcatgccgtcagct
ttgaaattactggcagaatctccttattgtttgtcaatagacaaggtgtttgttataggg
ggtggtcagatattaagggaagcactgaatgctcctggttgtgatgccatccacatcact
aaaattgagacaagcattgaatgtgacactttcattcccactattgacacttctgttttt
catccatggtattcatcagtaccattgttggaaaacaacattctatattcttttgtgact
tatgttcgtgtgaggagttctgccttggaatcttttgctttgagcagtggggtgaatttt
aatggtggttctgttccaaataagctcaagatacagggttttaccttcttgccgaagatg
atttttgagagacatgatgagtttatgtatctaagacaactaaaagaaattatctcaagt
ggcgctcataaagctgacaagacagggactggcactgtatcaaaatttggttgtcagatg
cgtttcaatctgcgtttgtcttttccgcttcttaccaccaagagagtattttggagaggt
gttgttgaagagcttttgtggtttattagtggttcaacaaatgcaaaggtgctgcagaag
aaagacattcatatatgggatggcaatgcatccagagagtaccttgacagtattggtttg
acagatagggaagagggggacttgggacccatatatgggttccagtggagacactttggt
gccaggtataccaacatgcatgctgactacatgggtaaaggatttgatcagttgcttgat
gttattgataagatcaagaataaacctgatgacaggcgtattatactctcttcttggaat
ccatctgatcttaaattgatggcacttccgccttgccacatgtttgcacaattttatgta
gccaatggggagctatcctgtcaaatgtatcagcgctctgctgatatgggtcttggtgtg
ccatttaacattgcttcttatgctttattgacatgcatgattgctcatgtttgtggtatt
ctccctggtgatttcatcctcataattggtgatgctcatatttataaaactcatattagg
cctctggaggagcagcttcagaaacttcctaaacctttccctattttgaagatcaatcca
cagaagaaggatattgaatcatttgtggcagctgattttgagcttataggttataatcct
caccagaagattgaaatgaaaatgtcagtgtag

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