KEGG   Xenopus laevis (African clawed frog): 108707262
Entry
108707262         CDS       T01010                                 
Symbol
hmgcr.S
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like isoform X2
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00900  Terpenoid backbone biosynthesis
xla01100  Metabolic pathways
Module
xla_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    108707262 (hmgcr.S)
Enzymes [BR:xla01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     108707262 (hmgcr.S)
SSDB
Motif
Pfam: HMG-CoA_red Sterol-sensing Patched
Other DBs
NCBI-GeneID: 108707262
NCBI-ProteinID: XP_018099920
Xenbase: XB-GENE-17334952
UniProt: A0A8J0UAZ5
Position
1S:172416636..172433987
AA seq 912 aa
MMGSRRFRLFLKHPIFLHPNTQLYDILNRANMLSRLFRMHGQFVASHPWEVIVGTVTLTI
CMMSMNMFTGNDKICGWNYACPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSK
YILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSKASALAKFALSSNS
QDEVRDNIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFAFM
TFFPACVSLVLELSRESREGRPIWQLGQFSSVLEEEEDNKPNPVTQRVKMIMSLGLVLVH
AHSRWISEPFSQNNTSISDHEVTTMLDDMMPKRVEPSMPLWQFYLSRMVTMDVEQIITLG
LALLLAVKYIFFEQTETESTFSMKNPIISPVAVQKKQVESCYRREQEKPVNVSTTEEASS
KAEKEAVIKPLPLETSPKAKFIVGDSSPIELSPEDKNSMFNLPEEPRPLEECVRILKNPD
KGAQYLTDAEVISLVNAKHIPAYKLETMMESPERGVAVRRQMLADKLPQPSALQSLPYKN
YNYSLVMGACCENVIGYMPIPVGVAGPLLLNNKEYQVPMATTEGCLVASTNRGCRAIMLG
GGARSRVLADGMTRGPVVRLPTACDAAEVKAWLDSTEGFKVIKDAFDSTSRFARLGRLQT
SVAGRNLYIRFQSKTGDAMGMNMISKGTEKALARLQEEFPDLHVLAVSGNYCTDKKPAAI
NWIEGRGKSVVCEAIIPAKVVREVLKSSTEALVEVNINKNLIGSAMAGSIGGYNAHAANI
VTAIYIACGQDAAQNVGSSNCITIMEATGPMNEDLYISCTMPSIEIGTVGGGTTLAPQQA
CLQMLGVQGASTEAPGKNARQLAQIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKMNL
QDLPGTCTKKAA
NT seq 2739 nt   +upstreamnt  +downstreamnt
atgatgggctcgagaaggtttcgactcttccttaagcaccctatatttctgcacccgaac
actcagctatacgatatccttaatagagccaacatgctgtccagactatttcgcatgcat
gggcagtttgtggcctctcatccctgggaggtcatcgttgggactgtgactctcacaatc
tgcatgatgtcaatgaacatgttcactgggaatgacaaaatctgtggctggaattatgct
tgccccaagtttgaagaagatgttctgagcagtgacatcatcatcctgacaatcacaaga
tgcatcgccatcctttacatttatttccagttccagaacctcagacagctcggctcaaaa
tacattttagggattgctgggcttttcaccatcttctcaagctttgtttttagcacagtg
gttattcacttcctggataaagaactgacaggcctaaacgaagctcttccatttttcctg
cttttgatcgatctttccaaggctagtgctttagccaaatttgctctaagttccaactca
caggatgaagtccgagacaatattgcccgtggcatggcaattctaggacctacctttacc
cttgatgcgcttgtagaatgtcttgtgattggagtcggtacaatgtcaggtgtgcggcag
ttagaaatcatgtgttgcttcggctgcatgtctgtccttgccaattattttgccttcatg
accttctttccagcttgtgtttcattagtgttagagctttctagagagagccgagagggc
cgtccaatctggcagcttggtcagttttctagtgtactagaagaagaggaggataataaa
ccaaatcctgttactcagagagtgaaaatgattatgtctctggggttggtcctggttcat
gctcatagtcggtggataagtgaacccttttcccaaaacaacacttcaatcagtgaccat
gaagttaccaccatgctggatgatatgatgccaaagagagttgagcctagcatgcctctc
tggcagttctatctttctagaatggtgaccatggatgtagaacagatcattactcttggt
cttgctctcctccttgccgtgaagtacatattctttgagcaaacagagacagaatcaacc
ttctctatgaagaacccgataatctcccccgtagcggtgcaaaagaagcaagtagagagt
tgctacagacgggaacaggaaaaaccagtcaacgtttccacaacagaagaagcttcatca
aaggcggaaaaggaggcagttataaagccattaccccttgagacatcacccaaagccaag
tttatagtgggagattcttctccaatagaattgtctccagaggataaaaattccatgttt
aatctaccagaggaaccgcgtccacttgaggaatgtgttcgtattcttaagaatccagat
aaaggagcacagtatctgactgatgcagaagtcattagccttgtgaatgccaagcatatc
cctgcctataaactggaaaccatgatggaatcccccgagaggggtgtggctgttcgcagg
caaatgttagctgataagctcccccaaccatcagcactgcagagtttgccttataagaac
tacaactactctttagtaatgggtgcttgttgcgagaatgtcatcgggtacatgcccatc
cctgtaggtgtagccggacctctcttgctgaacaacaaagagtatcaggtgcccatggca
acgactgaagggtgtcttgtggccagcacaaacagaggctgcagagccataatgctggga
ggaggtgccagaagtcgtgttctggctgatgggatgactcgtggtcccgttgttaggtta
ccaactgcctgtgatgcagcagaagtaaaggcctggctagacagtacagagggattcaaa
gtcataaaggatgcttttgatagcacaagcagatttgctcgactcgggagactacaaacc
agtgttgctggaaggaacctgtacatccgtttccagtctaaaacaggagatgccatggga
atgaacatgatttcaaaaggcactgaaaaggctcttgctagactacaagaagagttccct
gatctccatgttttagctgtcagtggcaactactgtacggataagaagccggctgctatt
aactggatagagggtagaggaaagtctgtggtttgtgaggccatcattccagccaaagtt
gtacgggaggttctaaagagctcaacagaagcattagttgaagtgaatatcaataagaat
ttgattggttctgctatggcgggaagcattggaggctacaatgcacatgctgcaaacatt
gtgacggccatttacattgcttgcggacaggatgctgctcagaatgtcgggagctccaac
tgcatcacaataatggaggctactggtcctatgaatgaagatttgtacatcagctgcaca
atgccctctatagaaattggaacagtaggaggtggaaccaccttggctccccagcaagct
tgcttacagatgctgggggtgcaaggagcaagtacagaggcaccagggaaaaatgcccgc
cagcttgctcagatagtgtgtggcacagtaatggccggggagctttcactaatggcagct
ttggctgcgggtcatctagtcaagagtcacatgatccataacaggtcaaaaatgaacctt
caggacctgccaggcacatgcacaaagaaagctgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (49)   

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