KEGG   Xenopus laevis (African clawed frog): 108718238
Entry
108718238         CDS       T01010                                 
Symbol
adam17.S
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17
  KO
K06059  disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla04148  Efferocytosis
xla04330  Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:xla00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    108718238 (adam17.S)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108718238 (adam17.S)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:xla01002]
    108718238 (adam17.S)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:xla04090]
    108718238 (adam17.S)
Enzymes [BR:xla01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.86  ADAM 17 endopeptidase
     108718238 (adam17.S)
Peptidases and inhibitors [BR:xla01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   108718238 (adam17.S)
CD molecules [BR:xla04090]
 Proteins
  108718238 (adam17.S)
SSDB
Motif
Pfam: Reprolysin_2 Reprolysin_5 ADAM17_MPD Disintegrin Reprolysin_3 Reprolysin_4 Pep_M12B_propep
Other DBs
NCBI-GeneID: 108718238
NCBI-ProteinID: XP_018121420
Xenbase: XB-GENE-17337566
UniProt: A0A1L8G4Z1 A0A974HI88
Position
5S:complement(125323099..125370577)
AA seq 855 aa
MFWSMCVLPVDFTNNMKSLRPLGGLSVTVVFIALLLCLVVAEAEHIPFGYQKEIPAKHQG
LDSMLSEYDVLSLSSIQQHSLRKRDLQTQSQIERMLSFTALQRHFQLYLASSTELFSENL
QALVLDGNGKEKKYQVKRSDFFTGHVVGEHNSKVLAHIGDGDFTARITTDGEEYNIEPLW
RFVENTSRDNMLVYRSEDIKDFSRLKSSKVCGYIQPKEDLFKNEQDTAEAPEGDGYLHRE
KRQRAAPDPMKNTCKMVVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSWDSQW
KGYGVQIEQIIVHKEPENVTQGQKHYNMAKSSPNPDKDAWDVKQLLEQFSFDISEKAAQV
CLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAIYLNTGLTSTKNYGK
TILTKEADLVTTHELGHNFGSEHDPDSMASCAPSEDHGGKFVMYPIAVSGDHENNKMFSG
CSRESILRTLMSKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHSDSCCTSDCKFKAGV
SCSDRNSPCCKGCQFETAQKKCQEAINATCKGESYCTGSSSECPTPGNAEDETVCVDLGK
CVNGECRPFCEIEKNLKSCACNDTEHSCKVCCRGENGICSPYVDKNKQFLYLRKGKPCTV
GFCDMNGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLVFWIPLSILVH
CVDKKLDKRYEETTKSLFTPSNMEMLSSLDSAPVRFVKPSPCAQATCRFQALQTVPVVPT
SATTKADHQRMDTIQEDPSVDSHLDDQFEEGPFPNSGSPAKSFEDLTDRPVVRSEKASSF
RLQRQGRVDSKETEC
NT seq 2568 nt   +upstreamnt  +downstreamnt
atgttctggtccatgtgtgtgctaccagtggactttacaaataacatgaaatctttgagg
cctttgggtggactgagtgtgactgtagtcttcattgctttgcttctttgtctggtggtg
gctgaagctgagcacattccatttggttaccagaaagagattcctgccaaacatcaaggt
ctcgactccatgctctccgagtacgacgtcctgtctttgtccagcattcagcaacattcc
ctgagaaagagggacctgcagactcagtcacagattgaaagaatgctgagcttcactgca
ctccagaggcattttcaattgtatttggcatcaagcacagagctcttctcagaaaatctt
caagcgctggtactggatgggaacggcaaggaaaagaaataccaagtgaagcggtcggat
ttctttactggacatgttgtgggtgagcataattccaaagttttggcacacattggcgat
ggagattttacagcgcgaataacaacagacggagaggaatataatattgagcccctatgg
cggtttgtggagaacacgtcaagagataacatgttggtttaccgctctgaagatataaaa
gacttttctcgcttgaagtcctcaaaggtctgcgggtacattcagcctaaggaagacctc
tttaaaaacgagcaggacacagcagaagcgcctgaaggtgatggctacttgcaccgagag
aaaaggcagagagctgcgccagaccccatgaagaatacttgcaaaatggtagttgtagcc
gaccatcggttcttcaagtatatgggtcgtggagaggagagtaccaccatcaactatttg
atagagctgattgacagagtggatgacatctacagaaacacctcctgggattcccagtgg
aaaggttatggcgtacagatagaacagattattgtacacaaggagccagagaatgtgaca
cagggacagaagcattacaatatggcaaaatcttctcctaatcctgacaaagatgcctgg
gatgtgaaacagctgttggagcaattcagctttgacatctctgagaaagcggcccaggtg
tgcttagctcatctcttcacctatcaggacttcgacatgggcaccctggggctggcatat
gttggatctcacaagccaaacactcacggaggcatttgtcccaaagcctatgaaaatgat
ttatccaagaaagcaatctatttaaatactggcctcaccagcacaaagaactacggcaaa
accattcttacaaaggaagcagaccttgtcactactcatgaacttggccataactttgga
tcagagcacgatcctgacagcatggcgtcctgtgcacccagcgaagatcacggcggaaaa
tttgtcatgtatcctatagctgtgagcggagaccatgaaaacaataagatgttctcgggc
tgcagcagagagtccatcttgagaacactaatgagcaagtctcccatctgcttcaaagag
cgcaacaacaaagtatgcggcaattcgcgggtggatgagggtgaggagtgtgaccccgga
ttgctgcaccagcacagtgattcctgctgtacttcagactgcaagtttaaagcaggagtg
agctgcagtgatcggaacagtccgtgctgcaaaggctgccagtttgaaacagcgcagaag
aagtgccaggaagctataaatgccacttgcaagggagagtcctactgtacagggagcagc
agtgaatgcccaacccctggcaatgcagaagatgaaacagtctgcgtagacttgggcaaa
tgtgtgaatggagagtgtcggccattctgtgagatagagaagaatctcaagtcctgcgcc
tgcaatgacactgaacattcctgcaaggtgtgttgtcggggtgaaaacgggatctgcagc
ccctacgttgataaaaacaaacagttcttgtacttacggaaaggaaaaccttgtaccgtt
ggcttctgtgatatgaacggaaagtgtgagaaacaagtgcaagatgtgattgagcgcata
tgggatttcattgacaaactcagcatcaacatgttcggaaagttcctggcagataacatt
gtaggatctgttgttgtgttttctttagtcttctggatcccactgagtattcttgtccac
tgtgtggacaagaaactggacaaacgttacgaagagactacaaagtctttattcactccc
agtaatatggaaatgctgagtagcctggactctgctccggtgcgctttgttaagccgtcc
ccttgtgcccaggcaacttgccgtttccaggccctgcagaccgttcccgtagttccaacc
tctgccaccactaaagccgatcaccagagaatggacacaattcaagaagaccccagcgtc
gactctcacctcgatgaccaatttgaagagggccctttccctaacagcggctcgccagca
aagtctttcgaagatctcacagaccggccagtggtgaggagcgagaaggcctcatccttt
agacttcaacggcagggccgggtagacagcaaggaaacagagtgctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (42)   

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