KEGG   Xenopus laevis (African clawed frog): 398985Help
Entry
398985            CDS       T01010                                 

Gene name
mapk1-a, erk, erk2, ert1, mapk, mapk1, mapk1a, mapk2, mpk1, p42mapk, prkm1, prkm2, xp42
Definition
mitogen-activated protein kinase 1 (EC:2.7.11.24)
Orthology
K04371  
mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
MAPK signaling pathway
ErbB signaling pathway
FoxO signaling pathway
Oocyte meiosis
mTOR signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Dorso-ventral axis formation
TGF-beta signaling pathway
VEGF signaling pathway
Focal adhesion
Adherens junction
Gap junction
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Melanogenesis
Salmonella infection
Module
MAPK (ERK1/2) signaling
Brite
KEGG Orthology (KO) [BR:xla00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    398985 (mapk1-a)
   04012 ErbB signaling pathway
    398985 (mapk1-a)
   04350 TGF-beta signaling pathway
    398985 (mapk1-a)
   04370 VEGF signaling pathway
    398985 (mapk1-a)
   04068 FoxO signaling pathway
    398985 (mapk1-a)
   04150 mTOR signaling pathway
    398985 (mapk1-a)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    398985 (mapk1-a)
  Cell growth and death
   04114 Oocyte meiosis
    398985 (mapk1-a)
  Cellular commiunity
   04510 Focal adhesion
    398985 (mapk1-a)
   04520 Adherens junction
    398985 (mapk1-a)
   04540 Gap junction
    398985 (mapk1-a)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    398985 (mapk1-a)
   04621 NOD-like receptor signaling pathway
    398985 (mapk1-a)
  Endocrine system
   04910 Insulin signaling pathway
    398985 (mapk1-a)
   04912 GnRH signaling pathway
    398985 (mapk1-a)
   04914 Progesterone-mediated oocyte maturation
    398985 (mapk1-a)
   04916 Melanogenesis
    398985 (mapk1-a)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    398985 (mapk1-a)
   04270 Vascular smooth muscle contraction
    398985 (mapk1-a)
  Development
   04320 Dorso-ventral axis formation
    398985 (mapk1-a)
 Human Diseases
  Infectious diseases
   05132 Salmonella infection
    398985 (mapk1-a)
Enzymes [BR:xla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     398985 (mapk1-a)
Protein kinases [BR:xla01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   398985 (mapk1-a)
Exosome [BR:xla04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   398985 (mapk1-a)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Xenbase: 
UniProt: 
AA seq 361 aa AA seqDB search
MAAAGAASNPGGGPEMVRGQAFDVGPRYINLAYIGEGAYGMVCSAHDNVNKVRVAIKKIS
PFEHQTYCQRTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK
TQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPD
HDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQL
NHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFN
PHKRIEVEAALAHPYLEQYYDPSDEPVAEAPFKFEMELDDLPKETLKELIFEETARFQPG
Y
NT seq 1086 nt NT seq  +upstreamnt  +downstreamnt
atggcagcggcaggagctgcgtctaaccccggcgggggtccggagatggtgcggggccag
gcgttcgacgtaggccctcgatacatcaatctggcttatatcggcgagggagcgtacggc
atggtgtgttctgcccatgacaatgttaacaaagttcgagttgctatcaagaaaatcagc
ccatttgagcatcagacatactgccagcgaacattgcgggagatcaaaatcttgctacgt
tttaaacatgaaaacatcattgggataaacgacattattcgcgctccaaccattgagcag
atgaaagatgtgtacattgtgcaggacctcatggagacagacctctataagctcctgaag
actcagcatcttagcaatgaccatatctgctatttcttgtaccagattctgagaggatta
aagtacatccattcagccaatgttctacatcgtgatcttaagccttcaaatttgctgctt
aacactacctgtgatctcaagatctgtgattttggattggctcgtgttgcagacccagat
catgatcacactggctttctcacagaatatgtagccactcgctggtacagagctcctgag
atcatgctgaattccaagggctataccaaatcaattgacatctggtctgttggctgcatt
cttgctgagatgctttctaatagacccatatttcctgggaaacattatcttgaccagctt
aatcacatacttggtattcttggatctccatctcaagaggacctaaactgtataatcaat
ttaaaagctaggaattacttgctttcccttcctcacaaaaataaggtgccatggaacaga
cttttccccaatgcagatcccaaagctctagacttactggacaagatgctgactttcaac
ccccataaaagaattgaagtagaggcagctttggctcatccttatctggagcagtattat
gacccaagtgatgagcctgtagctgaagctccctttaaatttgaaatggagcttgatgat
ttgcccaaggagactcttaaggagctaatttttgaagaaaccgctagattccagccaggg
tactga

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