KEGG   Xenopus laevis (African clawed frog): 399263
Entry
399263            CDS       T01010                                 
Symbol
top1.1.L, top1, top1.1, topi
Name
(RefSeq) DNA topoisomerase 1
  KO
K03163  DNA topoisomerase I [EC:5.6.2.1]
Organism
xla  Xenopus laevis (African clawed frog)
Brite
KEGG Orthology (KO) [BR:xla00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:xla03032]
    399263 (top1.1.L)
Enzymes [BR:xla01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     399263 (top1.1.L)
DNA replication proteins [BR:xla03032]
 Eukaryotic type
  DNA Topoisomerases
   399263 (top1.1.L)
SSDB
Motif
Pfam: Topoisom_I Topoisom_I_N Topo_C_assoc
Other DBs
NCBI-GeneID: 399263
NCBI-ProteinID: NP_001084031
Xenbase: XB-GENE-950006
UniProt: P41512
Position
9_10L:42609264..42640379
AA seq 829 aa
MSEDHVQNDSQIEAVFRVNDSHKHKKDKEHRHKEHKKDKDREKSKHNNSEHRDPSEKKHK
DKHKNNDKHREKDGEKHRERDGEKHRDKNGEKHRDGEKHKEKDIEKHKEVEKHRVKDGEK
HKEKDVEKHKEKDVEKHRDGEKHKHRDKDREKKKEEKMKSSSGGVKVKKENGFSSPVRVK
DEPEDQGFYVSPKENKAMKRPREDDEDYKPKKIKSEDDKKGKKRKQEEEDIKPKKKSKAK
GNEEGVKKKKVKKEEEEKWKWWEEERHRDGIKWKFLEHKGPVFAPPYEPVPDNVKFYYDG
NLVKLSPKAEEVATFFAKMLDHEYTTKDIFRKNFFKDWKKEMTTDERNLITNLSKCDFNA
MSLYFKEQSEARKNMTKEEKLKIKAENERLLQEYGYCIMDNHKERIANFRIEPPGLFRGR
GDHPKMGKLKKRIMPEDIIINCSKDSKIPVAPAGHKWKEVRHDGKVTWLVSWTENIQGSI
KYIMLNPSSRIKGEKDWQKYETARRLKMCVEKIRNTYKEDWKSKEMKVRQRAVALYFIDK
LALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVE
KRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDE
LTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARRE
FKSAKADAKVRRDEKTKKLVESKKKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYL
DPRISVAWCKKYGVPIEKIYNKTQRKNLLGPSIWQTTTSNFNAEQRCFS
NT seq 2490 nt   +upstreamnt  +downstreamnt
atgagtgaggatcatgtacagaacgactcgcagatcgaggctgtttttcgggtaaatgac
tctcacaaacacaagaaagacaaagaacatcgccacaaagaacacaagaaagacaaagac
cgtgaaaaatccaaacacaacaacagtgaacacagggatccttcagaaaagaagcataaa
gataaacacaaaaacaatgataaacatcgggagaaagatggggagaaacacagagaaaga
gatggggagaaacatagggacaaaaatggggagaaacacagagatggagaaaaacacaaa
gagaaagacattgagaaacacaaggaagttgagaaacatcgggtaaaggatggagagaaa
cacaaagagaaggatgtggagaagcacaaagagaaggatgtggagaagcatcgagatgga
gaaaagcataaacacagagataaagatcgggagaagaagaaagaggaaaaaatgaaatct
tccagcggcggtgttaaagtgaaaaaagaaaacggtttctctagtcctgtgcgagttaag
gatgagccagaagatcaaggcttctacgtgtcccccaaggaaaacaaggcaatgaagagg
ccaagagaggatgatgaggattacaaacctaagaagataaagtccgaagatgataaaaaa
gggaaaaagcgaaaacaagaggaagaggatattaagcccaagaaaaaaagtaaggccaaa
ggcaatgaagaaggagtgaaaaagaaaaaagtcaaaaaggaggaggaagagaagtggaaa
tggtgggaggaggagcggcaccgcgatggcattaagtggaagttcttggaacataaaggt
cctgtgtttgctcccccctatgaacccgtcccagacaatgtgaaattttactatgacggt
aatcttgtaaagcttagcccaaaagctgaagaagtggccacgttctttgcaaaaatgttg
gatcacgagtacactactaaggacatctttcgcaaaaacttcttcaaagactggaagaag
gagatgacgactgatgaaagaaacctcatcaccaacttgagcaaatgcgacttcaatgcg
atgagcctgtactttaaagagcaatccgaagcaaggaagaatatgaccaaggaagaaaag
ctgaaaatcaaagcagagaacgagcggttattgcaggagtacggctactgtatcatggac
aaccacaaggaacgtattgctaactttcgtatagaacctcctggtctgtttaggggcaga
ggagatcaccccaaaatgggcaaacttaagaaaaggataatgcctgaagacatcataatc
aactgcagcaaagactcaaaaattcctgttgctcctgctggtcacaagtggaaagaggtt
cggcatgatggcaaggtcacatggctggtatcatggactgaaaacattcagggttctatc
aaatacatcatgctcaaccctagctcccgaatcaagggtgagaaggactggcagaaatat
gagactgcccgaaggctcaagatgtgtgttgaaaagattcgaaatacctacaaagaagac
tggaagtccaaagagatgaaagttcggcagagagcagtagctctctactttatagacaag
cttgctttgagagctggcaatgaaaaggaagagggagaaaccgcagatacagtaggttgt
tgctccttgcgagtagaacacatcaatctgttccaagagttggacggccaagagtttgtg
gtggagtttgacttcccgggtaaagattccatccgctactacaacaaggtgcctgtggag
aaaagggttttcaaaaatcttcagctcttcatggaaaacaagcagcctgacgatgacctg
tttgacagactcaatacaagcattttgaacaagcaccttcaggacctgatggagggacta
acagccaaagtattcagaacatacaacgcctccatcaccctgcagcaacagctagatgag
cttactaactctgatgacaacgttcccgccaagatcttgtcctataaccgtgccaacaga
gcagtcgccatcctgtgtaaccatcagcgggcccctcctaaaacatttgagaaatctatg
atgaacctacagggcaagatagatgcgaagaaggatcagttggcagatgccaggagggag
ttcaagagtgcgaaagcagatgcgaaggtcaggcgggatgaaaaaaccaaaaagcttgta
gaaagcaaaaagaaagccgtgcagaggatagaagaacagctgatgaagttggaggtacaa
gcaacagacagggaagaaaacaaacagattgcccttggaacctccaaactcaactacctg
gatcccagaatctctgtggcatggtgtaaaaaatatggtgttcctattgaaaaaatctac
aacaaaacccagaggaaaaatttgcttgggccctcgatatggcagacgacgacttcaaat
tttaatgcagaacagcgttgtttttcttaa

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Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (54)   
   KEGG ORTHOLOGY (1)   
   RefGene (49)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (3)   
   Pfam (3)   
All databases (76)   

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