KEGG   Xenopus laevis (African clawed frog): 432172Help
Entry
432172            CDS       T01010                                 

Gene name
MGC78893, akt2-b
Definition
(RefSeq) RAC-beta serine/threonine-protein kinase B
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla04010  MAPK signaling pathway
xla04012  ErbB signaling pathway
xla04068  FoxO signaling pathway
xla04140  Autophagy - animal
xla04150  mTOR signaling pathway
xla04210  Apoptosis
xla04218  Cellular senescence
xla04261  Adrenergic signaling in cardiomyocytes
xla04370  VEGF signaling pathway
xla04371  Apelin signaling pathway
xla04510  Focal adhesion
xla04620  Toll-like receptor signaling pathway
xla04625  C-type lectin receptor signaling pathway
xla04910  Insulin signaling pathway
xla04914  Progesterone-mediated oocyte maturation
xla04920  Adipocytokine signaling pathway
xla04933  AGE-RAGE signaling pathway in diabetic complications
Module
xla_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:xla00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    432172 (MGC78893)
   04012 ErbB signaling pathway
    432172 (MGC78893)
   04370 VEGF signaling pathway
    432172 (MGC78893)
   04371 Apelin signaling pathway
    432172 (MGC78893)
   04068 FoxO signaling pathway
    432172 (MGC78893)
   04150 mTOR signaling pathway
    432172 (MGC78893)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    432172 (MGC78893)
  Cell growth and death
   04210 Apoptosis
    432172 (MGC78893)
   04218 Cellular senescence
    432172 (MGC78893)
  Cellular community - eukaryotes
   04510 Focal adhesion
    432172 (MGC78893)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    432172 (MGC78893)
   04625 C-type lectin receptor signaling pathway
    432172 (MGC78893)
  Endocrine system
   04910 Insulin signaling pathway
    432172 (MGC78893)
   04920 Adipocytokine signaling pathway
    432172 (MGC78893)
   04914 Progesterone-mediated oocyte maturation
    432172 (MGC78893)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    432172 (MGC78893)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    432172 (MGC78893)
Enzymes [BR:xla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     432172 (MGC78893)
Protein kinases [BR:xla01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   432172 (MGC78893)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr PH Pkinase_C Kinase-like PH_11 Seadorna_VP7
Motif
Other DBs
NCBI-GeneID: 432172
NCBI-ProteinID: NP_001085101
UniProt: Q6IP76
Position
8S
AA seq 485 aa AA seqDB search
MNEVMVIKEGWLQKRGEYIKTWRPRYFLLKSDGSFIGYKEKPDSTEHSLLPPLNNFSVAE
CQLMKTERPRPNTFVIRCLQWTTVIERTFHVDTPEEREEWIIAIQTVANGLKNQVPEDEE
EEAMEVKYGSPSDVSSAEQMDVAMSKGRPKVTMNDFDYLKLLGKGTFGKVILVREKATGL
YYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGE
LFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDGHVKITDFGL
CKEGITDGATMRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHE
RLFELILMEETRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPDDAQEVMSHGFFASINWQD
VTERKLSPPFKPQVTSEIDTRYFDDEFTAQSITLTPPDRYDNLDALESEQRPHFPQFSYS
SSIRE
NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt
atgaatgaagtgatggtgattaaagaaggttggcttcaaaaaagaggggagtatataaaa
acatggagaccaagatatttccttctgaaaagtgatggttcatttattggctataaagag
aaacctgactccacagagcacagtcttcttcctcccctcaataacttctctgttgcagaa
tgtcagctaatgaagacggagcggcctaggcccaacacatttgtgattcggtgcttacaa
tggacgacagttattgaacggacttttcatgttgacacaccagaggaaagggaagaatgg
attattgccatccagacagtggccaatggcctgaagaaccaggtacctgaagatgaagag
gaggaagccatggaagttaagtatggctcccccagtgatgtctcgagtgcagagcagatg
gacgttgcaatgtccaaagggcgccccaaagtgaccatgaatgattttgactacctcaaa
ttgctgggaaaagggacctttgggaaggttatccttgttcgagagaaagctaccggactt
tactatgctatgaagatccttcgaaaagaggtcataattgctaaggatgaagttgctcat
acactaacagaaagcagagttttgcagaacacaaaacacccgtttttaacgggattaaag
tatgcatttcagaccagtgacagactctgctttgttatggaatatgctaatggtggagag
ctttttttccacctttcacgagaacgagtttttacagaggacagagcacgcttttatggt
gcagaaattgtgtcggctttagaatatctacattctcgaaacgtagtatacagagacatt
aagctggagaatctcatgctggataaggatggccatgtcaagattacagattttggtttg
tgtaaggaaggcatcacagatggagccactatgaggactttctgtggcacaccagagtat
cttgcgcctgaggtgcttgaagataacgactatggccgagccgtggactggtggggtctc
ggagttgtgatgtatgaaatgatgtgtggccgattgcccttttataaccaagaccatgag
aggttattcgaacttatcctcatggaggagacccgctttccccgtacattaagtccagag
gcaaaatctctgcttgctgggcttttgaaaaaggatcctaaacagagattaggagggggt
cctgatgatgcccaagaggtcatgtcgcatggattctttgcttctatcaattggcaagat
gtaacggagagaaagctctcccctcctttcaagccacaagtcacatccgagattgacaca
agatattttgatgacgagtttacggctcagtctataacattgacccctcctgacagatat
gataaccttgatgccttagaatcagagcagcgccctcattttcctcaattctcttattct
tcaagcatacgggaataa

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