KEGG   Xenopus laevis (African clawed frog): 446641
Entry
446641            CDS       T01010                                 
Symbol
mthfd2l.S
Name
(RefSeq) bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00670  One carbon pool by folate
xla01100  Metabolic pathways
xla01240  Biosynthesis of cofactors
Module
xla_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    446641 (mthfd2l.S)
Enzymes [BR:xla01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     446641 (mthfd2l.S)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     446641 (mthfd2l.S)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH CcmH
Other DBs
NCBI-GeneID: 446641
NCBI-ProteinID: XP_018109776
Xenbase: XB-GENE-6256673
UniProt: Q6DDQ6 A0A974D9K1
Position
3S:complement(32497916..32515900)
AA seq 335 aa
MATITSLRSLCCAVRAQVRAIHCTPCRNEAVIISGRKLARQIRQEARHEVEQWVAAGNKR
PHLSVVLVGDNPASHSYVLNKTKAAADVGISSETIIKPTSITEEELLDLINKLNNDDHVD
GLLVQLPLPEHLDERAICNAVTPDKDVDGFHVVNVGKMCLDQYSMLPATPWGVWEIIKRT
GIPTLGKNVVVAGRSKNVGMPIAMLLHTDGRHERPGGDATVTISHRYTPKEQLKMHTKLA
DIVVAAAGIPNLITADMIKEGAAVIDVGINRVQDPVTGKPKLVGDVDFEGVRKKASYITP
VPGGVGPMTVAMLMKNTIIAAKKMLKPTELQALAM
NT seq 1008 nt   +upstreamnt  +downstreamnt
atggcaaccattacatccctccggtctctgtgctgcgctgtgagagcccaggttcgggcg
atccactgtaccccgtgcaggaatgaggcagtcatcatctctggcagaaagctggcaagg
caaatccggcaagaggcacggcacgaagtggaacagtgggtggcagccggcaacaagaga
ccacacctcagtgtcgttctggttggagacaaccctgcaagccattcctacgtgttaaac
aagacaaaagctgctgcagatgtgggtatcagcagtgaaactataatcaagccaacatcc
atcacagaagaggagctcttggatctcatcaacaagctcaacaacgatgatcatgtcgat
gggcttcttgtgcagctgcctctcccagaacacttagatgagagggcgatctgcaacgct
gttactccagacaaagatgtagatggtttccatgtggtgaacgtgggcaaaatgtgcctg
gaccagtactccatgctgccggccaccccttggggagtgtgggagattattaagagaaca
ggaatccctactcttgggaagaatgtggtagtagctggaagatctaaaaatgttgggatg
cccatagcaatgctgctgcacacggatggaaggcacgagcgtcctggaggcgatgctaca
gtgacaatctctcatcgctacactcctaaagaacagctgaagatgcacaccaaactggct
gatattgtcgttgcagctgcaggcatacctaaccttataacagctgacatgataaaggaa
ggtgctgccgtaattgatgttggcattaaccgcgtgcaggatccagttaccggcaaacca
aaacttgtcggagatgtggattttgaaggtgtaagaaagaaagcaagttacatcactccg
gtgccggggggagtcggacctatgactgttgccatgctaatgaagaatacaatcattgct
gcaaagaaaatgttaaaacccacagagctccaggcccttgccatgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (38)   

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