KEGG   Xenopus laevis (African clawed frog): 446786Help
Entry
446786            CDS       T01010                                 

Gene name
pik3r2
Definition
(RefSeq) phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla04012  ErbB signaling pathway
xla04068  FoxO signaling pathway
xla04070  Phosphatidylinositol signaling system
xla04140  Autophagy - animal
xla04150  mTOR signaling pathway
xla04210  Apoptosis
xla04218  Cellular senescence
xla04370  VEGF signaling pathway
xla04510  Focal adhesion
xla04620  Toll-like receptor signaling pathway
xla04625  C-type lectin receptor signaling pathway
xla04810  Regulation of actin cytoskeleton
xla04910  Insulin signaling pathway
xla04914  Progesterone-mediated oocyte maturation
xla04933  AGE-RAGE signaling pathway in diabetic complications
Module
xla_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:xla00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    446786 (pik3r2)
   04370 VEGF signaling pathway
    446786 (pik3r2)
   04068 FoxO signaling pathway
    446786 (pik3r2)
   04070 Phosphatidylinositol signaling system
    446786 (pik3r2)
   04150 mTOR signaling pathway
    446786 (pik3r2)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    446786 (pik3r2)
  Cell growth and death
   04210 Apoptosis
    446786 (pik3r2)
   04218 Cellular senescence
    446786 (pik3r2)
  Cellular community - eukaryotes
   04510 Focal adhesion
    446786 (pik3r2)
  Cell motility
   04810 Regulation of actin cytoskeleton
    446786 (pik3r2)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    446786 (pik3r2)
   04625 C-type lectin receptor signaling pathway
    446786 (pik3r2)
  Endocrine system
   04910 Insulin signaling pathway
    446786 (pik3r2)
   04914 Progesterone-mediated oocyte maturation
    446786 (pik3r2)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    446786 (pik3r2)
Membrane trafficking [BR:xla04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    446786 (pik3r2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3K_P85_iSH2 SH2 IncA Transcrip_act CC2-LZ
Motif
Other DBs
NCBI-GeneID: 446786
NCBI-ProteinID: NP_001086951
UniProt: Q6DD15
Position
4S
AA seq 457 aa AA seqDB search
MYNTVWNMDQDDADWREVMMPYSTELIFYIEMDPPALPPKPPKSMTSLSTDGSKENSTSS
LQDAEWYWGDIAREEVNDKLRDMPDGTFLVRDASSKVQGDYTLTLRKGCNNKLIKIYHQD
GKYGFSDPLTFNSVVELINHYRHESLAQYNPKLDVKLLYPVSRYQQDQLVKEDNIDAVGR
KLQEYHSQFQDKSKAYDQLYEEYTKTSQEIQMKRTAIEAFNETIKIFEEQCHTQECYSKD
YMEHFNREGNEKEMERIIMSYEKLKSRLGDVHDSKLRLEQDLKTQALDNREIDKKMNSIK
PDLIQLRKIRDQYLVWLNHKGVRQKRINDWLGIKNENIDDEEPDNLPHFDEKTWFVGDLG
RIQAEELLSGKPDGAFLIRESSKKGCYACSVVADGDVKHCVIYSTSRGYGFAEPYNLYST
LKELVLHYQHTSLVQHNDSLNVRLAYPVYAQMPSLCR
NT seq 1374 nt NT seq  +upstreamnt  +downstreamnt
atgtacaacactgtgtggaatatggaccaagatgatgcagactggagggaagttatgatg
ccttattccaccgaactgatcttttatatagagatggaccccccagcacttcctcctaaa
ccaccaaaatccatgacttcattgtctacagacggaagcaaagagaactccacttcttct
cttcaggatgccgaatggtactggggagacatcgccagggaagaggtaaatgataaactt
cgtgatatgccagatggtaccttcctggttcgagatgcatcttccaaagttcaaggcgat
tatactttgacactgcggaaagggtgcaataacaaactgataaagatttatcatcaggat
ggcaaatatggtttttctgatccgttgacatttaactctgttgtggagttgataaaccat
tatagacacgaatccttggcacaatacaatcctaaactggatgtgaagttattatatcca
gtatcaagataccagcaggatcagcttgttaaagaagataacattgatgctgttggtagg
aaacttcaagaataccatagtcagtttcaggataaaagcaaagcatacgatcaattgtac
gaagaatatacaaaaacatcacaggaaattcagatgaagagaacagcaattgaagccttt
aacgagactattaaaatatttgaagaacagtgccatacacaagaatgctatagtaaagat
tacatggagcatttcaatagggagggcaatgaaaaggaaatggaaaggataataatgagt
tatgaaaaattaaaatctcgtttgggtgacgttcatgacagtaaattacgcctggaacaa
gacttgaagacgcaagctttagacaatagagaaatagacaagaaaatgaacagtatcaaa
cctgatcttattcagctacgtaaaataagagatcaataccttgtatggcttaatcacaaa
ggagtgaggcaaaaacgaataaatgactggctgggaatcaagaatgaaaatattgatgat
gaggagcctgataaccttccacattttgatgagaaaacctggtttgttggtgatcttggc
cgtatacaagcagaagaattactcagtggaaagccagatggagcctttctaattcgagaa
agtagcaagaagggatgctatgcctgttctgttgtggctgatggtgatgtgaagcactgt
gtcatctacagtacgtcaagggggtatggatttgcagagccatacaatctctacagtaca
ctaaaagagttagtccttcattaccagcatacatcccttgtacaacataatgattctctc
aatgtcaggcttgcttatccagtctacgcacagatgccctccctctgcagataa

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