KEGG   Xiphophorus maculatus (southern platyfish): 102226157Help
Entry
102226157         CDS       T02923                                 

Definition
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
xma  Xiphophorus maculatus (southern platyfish)
Pathway
xma00562  Inositol phosphate metabolism
xma04012  ErbB signaling pathway
xma04068  FoxO signaling pathway
xma04070  Phosphatidylinositol signaling system
xma04140  Autophagy - animal
xma04150  mTOR signaling pathway
xma04210  Apoptosis
xma04218  Cellular senescence
xma04370  VEGF signaling pathway
xma04510  Focal adhesion
xma04620  Toll-like receptor signaling pathway
xma04625  C-type lectin receptor signaling pathway
xma04810  Regulation of actin cytoskeleton
xma04910  Insulin signaling pathway
xma04914  Progesterone-mediated oocyte maturation
xma04933  AGE-RAGE signaling pathway in diabetic complications
Module
xma_M00676  PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:xma00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102226157
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    102226157
   04370 VEGF signaling pathway
    102226157
   04068 FoxO signaling pathway
    102226157
   04070 Phosphatidylinositol signaling system
    102226157
   04150 mTOR signaling pathway
    102226157
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    102226157
  Cell growth and death
   04210 Apoptosis
    102226157
   04218 Cellular senescence
    102226157
  Cellular community - eukaryotes
   04510 Focal adhesion
    102226157
  Cell motility
   04810 Regulation of actin cytoskeleton
    102226157
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    102226157
   04625 C-type lectin receptor signaling pathway
    102226157
  Endocrine system
   04910 Insulin signaling pathway
    102226157
   04914 Progesterone-mediated oocyte maturation
    102226157
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    102226157
Enzymes [BR:xma01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102226157
Membrane trafficking [BR:xma04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    102226157
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_p85B PI3K_C2 DUF2321
Motif
Other DBs
NCBI-GeneID: 102226157
NCBI-ProteinID: XP_005805274
Ensembl: ENSXMAG00000000586
UniProt: M3ZEF9
Position
9
AA seq 1074 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRNASGPHSRALYVYPPSVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLTRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEASSKSLWSINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLPYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMNAVEDHANWIISRELGFNFNLSVNHSGTQQSSRVARDHALTESDSEQMRQL
SNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDDVAQMYCLLKEWPSIR
PEQAMELLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLL
KKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLIN
LTDILKQEKKDETQKVQMKFLVDQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRIMSS
AKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRML
PYGCLSLGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGETYDMAV
DLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPF
VLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQ
SFDDIAYIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq 3225 nt NT seq  +upstreamnt  +downstreamnt
atgcctccaaggccgtcctcaggggagctatggggcatccacctgatgcccccaaggatc
ctagtggactgcctgctgcccaatgggatgattctgaccttggagtgtctccgagaggcc
acgctaatcaccatcaagcatgagttgttcaaggaggccagaaaatatcccctccatcac
ctcctgcaggaggaaacctcctacatttttgtcagtgttacacaggaagctgagcgggag
gagttctacgatgagactcgaaggctgtgtgaccttcgactcttccagcctttcctcaaa
gtgattgagccagtcggcaacagagaggaaaagatcctgaacagagagatcggttttgcc
attggcatgcctgtgtgtgagttcgacctggtgaaggacccagaggtccaggacttcagg
agaaacatcctgaatgtttgtaaagactctgtggagctgagaaacgccagcggtccccac
agcagagcgctgtacgtttacccccccagcgtcgagtcgacacaggaacttcccaaacac
atctatagcaaactggacaaaggtcagattattgttgtaatatgggtgatcgtttcccca
aacaatgacaagcaaaagtatacactaaagatcaaccatgactgtgtgccggaacaggtg
attgcagaggccattcgcaagaagacgcgcagcatgctgttgtccccagagcagttgaag
atgtgtgttcaagaatatcagggcaaatacatcctcaaagtttgtggctgtgacgaatac
ctgctggaaaagtatcctataagccagtacaagtacatccgtagttgcatcatgttgacc
aggatgccaaacctgatgctaatggctaaggacagcctgtacactcagctgcctactgat
aacttcgtcatgccatcatactctcgacgtatctccacggcaacgtcgtacatgaatgga
gaggcttcgtccaagtcgctgtggagcatcaatgggactctgcgaatacgaatcctctgc
gccacctacgtcaacgtgaacatacgggacatagacaagatttatgtgaggactggaatt
taccacggaggtgaacaaatgtgtgacaacgtcaacacacagagagtaccctgctctaat
cccaggtggaatgagtggctcccgtatgacatgtacatcccggacatcccccgagctgcc
aggctctgcctctccatctgctctgttaaaggcagaaagggagccaaggaggaacactgt
ccactagcttggggcaacattaacctatttgactacactcacactctggtggccaacaag
atggctctgaacctctggccagtccctcatggccttgaagacctcctcaacccaatagga
gtcactggatctaatcccaataaggaaacgccatgtctggagctggagtttgaccacttc
agctgtcctgtcaaatacccagacatgaatgcagtggaagatcatgcaaactggatcatc
tccagggaactggggtttaacttcaatctctcagtcaaccactcgggaactcaacagagc
agtcgggtggccagagatcacgccctgacggaaagcgacagcgaacagatgcgacagctg
agtaacagggaccctctgtctgaaatcactgagcaggagaaagacttcctctggagacac
aggcattactgtatgaacatcccagagatccttcccaagatacttcttgctgtcaaatgg
aactccagagatgatgtagcgcagatgtattgtttgttgaaggaatggccatcgatccgt
ccagaacaggccatggagctgctggactgtaattacccagaccccatggtcagacacttc
gctgtacgctgccttgacaaatacttgaccgacgataaactctcccagtaccttatccag
cttgttcaggtattaaaatacgagcagtatcttgacagtccgctagctcgctttctcctc
aaaaaggccctgaccaatcaaaggataggccatttcttcttctggcatctcaagtcagaa
atgcacaacaaaactgtgagccagaggtttgggctgctgctggaggcttactgcagggct
tgtggcatgtacctcaaacacctgagcaggcaggtggaagccatggagaagcttatcaac
ctcaccgacatactcaaacaggaaaagaaggatgagacacaaaaggtccagatgaagttt
cttgtagaccagatgaagagacccgactacatggacgctctgcagagcttcacctctcca
ctcaaccctgcacatcagctgggaaatctgaggttggaggagtgcaggatcatgtcatcc
gcaaagagaccgctgtggctcaactgggagaatcctgacatcatgtccgagttactgttt
cagaataatgagatcatcttcaaaaacggagatgatttgcggcaggatatgctgacgctg
cagataatcagaatcatggagaacatttggcagaaccagggactggacctacggatgctc
ccctacggctgtctgtctctgggagactgcgtgggcctgatagaggtggttcgaaactcc
cacaccatcatgcagattcagtgcaaaggaggcttgaaaggagccttgcagttcaactcc
aacacgctgcatcagtggctcaaggacaaaaacaaaggagagacgtatgacatggctgtg
gatctgtttacgaggtcctgcgctggctactgtgtagccacgtttattctggggatcgga
gaccggcacaacagcaacattatggtcaaagatgacggacagttgtttcatatagatttt
ggccatttcttggatcacaagaagaagaaatttggctacaagagagagcgagtcccgttc
gtactgactcaagacttcctcatcgtcatcagtaagggatcccaggagtgcacaaagacc
aaagagtttgaaaggttccaggaaatgtgctacaaagcgtacctggccatccgccagcac
gccaacctcttcatcaacctgttctccatgatgctgggctccggcatgcccgagctgcag
tcgttcgacgacatcgcctacatccggaagacgctggcgctggagaaaaccgagcaggag
gctttggattatttcatgaagcagatgaacgacgcccaccatggaggttggaccaccaag
atggactggattttccacacgattcggcagcatgcactaaactaa

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