KEGG   Xenopus tropicalis (western clawed frog): 100144924Help
Entry
100144924         CDS       T01011                                 

Gene name
pik3ca, PI3-kinase, PI3K-alpha, pi3-k, pi3k
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
xtr  Xenopus tropicalis (western clawed frog)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:xtr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100144924 (pik3ca)
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    100144924 (pik3ca)
   04370 VEGF signaling pathway
    100144924 (pik3ca)
   04630 Jak-STAT signaling pathway
    100144924 (pik3ca)
   04068 FoxO signaling pathway
    100144924 (pik3ca)
   04070 Phosphatidylinositol signaling system
    100144924 (pik3ca)
   04150 mTOR signaling pathway
    100144924 (pik3ca)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100144924 (pik3ca)
  Cell growth and death
   04210 Apoptosis
    100144924 (pik3ca)
  Cell communication
   04510 Focal adhesion
    100144924 (pik3ca)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100144924 (pik3ca)
  Endocrine system
   04910 Insulin signaling pathway
    100144924 (pik3ca)
   04914 Progesterone-mediated oocyte maturation
    100144924 (pik3ca)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100144924 (pik3ca)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100144924 (pik3ca)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Xenbase: 
UniProt: 
Position
Un
AA seq 1065 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
VFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRLYCRNIPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCLEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVN
QRIGHFFFWLLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
NT seq 3198 nt NT seq  +upstreamnt  +downstreamnt
atgccgccaagaccttcctctggtgaactatggggcatccatttgatgcccccaagaatt
ctagtggaatgcctattaccaaatggaatggtggtggttttagaatgtcttcgcgaagcg
acccttgtgaatatcaaacatgagctctttaaagaggcccgaaagtacccactttaccat
ctactccaagatgagtcctcttatatttttgtgagtgttacccaggaagcagaaagagaa
gaattttttgacgagacccgccgcctctgtgatcttcgactgttccaacctttcttgaaa
gtagttgagcctgttggaaacagagaagagaaaatacttaatcgagaaatcggctttgcc
attggaatgccagtttgcgaatttgatatggtaaaggattcagaggttcaggattttaga
aaaaatatccttaatgtttgtaaagattcagttgaacttcgtgatgctaatggaccgatc
agcagagcattgtatgtttacccacctaatgtagagtcctcttcagagcttcccaaacac
atagaaagcaagctagataaagggcaaataattgtggtcatatgggtcattgtatctcct
aacaatgaaaagcagaagtattctttgaagataaaccatgattgtgtgccagaacatgta
atagctgaagctatcaggaagaaaacaaggagcatgctactgtcgtcagaacagctaaag
ctttgcgttctagagtaccaaggaaaatacatcttgaaagtttgtggatgtgatgagtat
ttgttggaaaagtatccattgagtcagtataagtatataagaagctgtataatgcttggt
cggatgcctaatttaatgttaatggctaaagatagcctgtacagtcaaattccagtggat
gtatttacaatgccatcgtattcaaggaggatttccacagcagcaccatacatgaacgga
gaagcttcagccaagtcattgtgggcaatcaacagtactcttagaataaaaatcctttgt
gccacatatgtcaatgtaaacattcgagacattgataagatttatgttcgaactggcatc
tatcatggagttgagccattatgtgacaatgttaacactcagagggtgccttgttcaaat
ccaagatggaatgaatggcttttatatgatatgttcattcctgatttaccccgagctgcg
cggctttgcctctccatctgctccgtaaagggaaggaagggtgccaaagaagagcactgc
cctttagcttggggaaacataaacctgtttgactacacagatactctggtgtctggcaaa
atggctctaaatttgtggcctgtacctcatgggctagaggacttgttaaatcctattgga
gtgagtggctccaatcctaataaggaaacgccctgtttggaactagaatttgactgtttc
agtagcccggtcaaatttcctgatatgacagcaatagaagatcatgcaaataaagttctg
gaacgagaaatgggctataattacagccattctggactgagtaacagaattgttagagaa
aatgaagtaagagaaagtgacaaagagcagctcaaagccatttctaatcgtgaccctctt
tctgaaattactgaacaagaaaaagaattcctttggagccacagactttattgtcgaaat
atacctgaaattcttcctaagctgcttctgtctgtgaaatggaattgcagagatgatgtt
tcacagatgtattgtcttttaaaagagtggcctgccatccggccagaacaagcaatggaa
ctgttggattttaattacccagatcggattgtaagatcatttgcggtttcttgccttgag
aagtatttgacagatgataagctgtcgcagtatttgattcaacttgtgcaggttatgaaa
tatgagcagtacttggacaaccatctagttagatttctgctgaaaaaggctctggtcaat
caaagaataggacatttctttttctggcttttaaagtcagaaatgcacaacaaaactgtc
agccaaaggtttggtcttttgctggaatcctattgccgtgcatgtggaatgtatttaaag
catttaagtaagcaggtggaagctatggaaaaactgatcaacctcacagatattctaaag
caggagaagaaggatgagacacaaaaggtgcaaatgaagttcctggttgaacaaatgaag
cggccagattttatggatgcattgcaaggatttacgtctcctctgaatcctgctcaccag
ttgggaaacctcaggcttgaagaatgcaggataatgtcatctgcaaaaagaccactgtgg
ttaaactgggaaaatccagatattatgtcagagatgctgtttttgaataatgagatcatc
tttaaaaatggcgatgatttacgacaagatatgctcacgcttcagatcataagaatcatg
gaaaacatttggcaaaatcagggccttgatttacggatgttgccgtatggttgcctgtca
atcggggattgtgttggacttattgaagtagtaaggtgttcacataccattatgcagatt
caatgcaaaggaggtttgaaaggagcattgcagttcaacagtcacacattgcaccagtgg
ctcaaggataaaaacaagggtgaaacgtatgatgctgccattgatctattcactcgatcg
tgcgctggttactgtgttgcaacttttattcttggaataggtgatcgccataacagtaac
attatggttaaagacaatgggcaactgtttcacatagattttggccactttctggatcac
aaaaagaagaaatttggctataaacgtgaaagggtaccgtttgtcttgactcaagatttt
ctgattgtgatcagcaagggaattcaagaatgcacgaaaaccagggattttgagagattt
caagagatgtgttacaaagcttacttagcaatccgtcagcatgccaaccttttcatcaac
ttgttctctatgatgcttggctctggaatgcctgaactgcaatcttttgatgatattgca
tatattcgaaaaacattagcattggataaaactgaacaagaggctttggaatacttcatg
aagcagatgaatgacgcacatcatggtggctggacaacaaaaatggactggatcttccat
acaataaagcatctttaa

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