KEGG   Xenopus tropicalis (western clawed frog): 100144924Help
Entry
100144924         CDS       T01011                                 

Gene name
pik3ca, PI3-kinase, PI3K-alpha, pi3-k, pi3k
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
xtr  Xenopus tropicalis (western clawed frog)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:xtr00562]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:xtr04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:xtr04370]
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:xtr04630]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:xtr04068]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:xtr04070]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:xtr04150]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:xtr04810]
Cellular Processes; Cell growth and death; Apoptosis [PATH:xtr04210]
Cellular Processes; Cell communication; Focal adhesion [PATH:xtr04510]
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:xtr04620]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:xtr04910]
Organismal Systems; Endocrine system; Progesterone-mediated oocyte maturation [PATH:xtr04914]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:xtr04261]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Xenbase: 
UniProt: 
Position
Un
AA seq 1065 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVD
VFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRLYCRNIPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCLEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVN
QRIGHFFFWLLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGETYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
NT seq 3198 nt NT seq  +upstreamnt  +downstreamnt
atgccgccaagaccttcctctggtgaactatggggcatccatttgatgcccccaagaatt
ctagtggaatgcctattaccaaatggaatggtggtggttttagaatgtcttcgcgaagcg
acccttgtgaatatcaaacatgagctctttaaagaggcccgaaagtacccactttaccat
ctactccaagatgagtcctcttatatttttgtgagtgttacccaggaagcagaaagagaa
gaattttttgacgagacccgccgcctctgtgatcttcgactgttccaacctttcttgaaa
gtagttgagcctgttggaaacagagaagagaaaatacttaatcgagaaatcggctttgcc
attggaatgccagtttgcgaatttgatatggtaaaggattcagaggttcaggattttaga
aaaaatatccttaatgtttgtaaagattcagttgaacttcgtgatgctaatggaccgatc
agcagagcattgtatgtttacccacctaatgtagagtcctcttcagagcttcccaaacac
atagaaagcaagctagataaagggcaaataattgtggtcatatgggtcattgtatctcct
aacaatgaaaagcagaagtattctttgaagataaaccatgattgtgtgccagaacatgta
atagctgaagctatcaggaagaaaacaaggagcatgctactgtcgtcagaacagctaaag
ctttgcgttctagagtaccaaggaaaatacatcttgaaagtttgtggatgtgatgagtat
ttgttggaaaagtatccattgagtcagtataagtatataagaagctgtataatgcttggt
cggatgcctaatttaatgttaatggctaaagatagcctgtacagtcaaattccagtggat
gtatttacaatgccatcgtattcaaggaggatttccacagcagcaccatacatgaacgga
gaagcttcagccaagtcattgtgggcaatcaacagtactcttagaataaaaatcctttgt
gccacatatgtcaatgtaaacattcgagacattgataagatttatgttcgaactggcatc
tatcatggagttgagccattatgtgacaatgttaacactcagagggtgccttgttcaaat
ccaagatggaatgaatggcttttatatgatatgttcattcctgatttaccccgagctgcg
cggctttgcctctccatctgctccgtaaagggaaggaagggtgccaaagaagagcactgc
cctttagcttggggaaacataaacctgtttgactacacagatactctggtgtctggcaaa
atggctctaaatttgtggcctgtacctcatgggctagaggacttgttaaatcctattgga
gtgagtggctccaatcctaataaggaaacgccctgtttggaactagaatttgactgtttc
agtagcccggtcaaatttcctgatatgacagcaatagaagatcatgcaaataaagttctg
gaacgagaaatgggctataattacagccattctggactgagtaacagaattgttagagaa
aatgaagtaagagaaagtgacaaagagcagctcaaagccatttctaatcgtgaccctctt
tctgaaattactgaacaagaaaaagaattcctttggagccacagactttattgtcgaaat
atacctgaaattcttcctaagctgcttctgtctgtgaaatggaattgcagagatgatgtt
tcacagatgtattgtcttttaaaagagtggcctgccatccggccagaacaagcaatggaa
ctgttggattttaattacccagatcggattgtaagatcatttgcggtttcttgccttgag
aagtatttgacagatgataagctgtcgcagtatttgattcaacttgtgcaggttatgaaa
tatgagcagtacttggacaaccatctagttagatttctgctgaaaaaggctctggtcaat
caaagaataggacatttctttttctggcttttaaagtcagaaatgcacaacaaaactgtc
agccaaaggtttggtcttttgctggaatcctattgccgtgcatgtggaatgtatttaaag
catttaagtaagcaggtggaagctatggaaaaactgatcaacctcacagatattctaaag
caggagaagaaggatgagacacaaaaggtgcaaatgaagttcctggttgaacaaatgaag
cggccagattttatggatgcattgcaaggatttacgtctcctctgaatcctgctcaccag
ttgggaaacctcaggcttgaagaatgcaggataatgtcatctgcaaaaagaccactgtgg
ttaaactgggaaaatccagatattatgtcagagatgctgtttttgaataatgagatcatc
tttaaaaatggcgatgatttacgacaagatatgctcacgcttcagatcataagaatcatg
gaaaacatttggcaaaatcagggccttgatttacggatgttgccgtatggttgcctgtca
atcggggattgtgttggacttattgaagtagtaaggtgttcacataccattatgcagatt
caatgcaaaggaggtttgaaaggagcattgcagttcaacagtcacacattgcaccagtgg
ctcaaggataaaaacaagggtgaaacgtatgatgctgccattgatctattcactcgatcg
tgcgctggttactgtgttgcaacttttattcttggaataggtgatcgccataacagtaac
attatggttaaagacaatgggcaactgtttcacatagattttggccactttctggatcac
aaaaagaagaaatttggctataaacgtgaaagggtaccgtttgtcttgactcaagatttt
ctgattgtgatcagcaagggaattcaagaatgcacgaaaaccagggattttgagagattt
caagagatgtgttacaaagcttacttagcaatccgtcagcatgccaaccttttcatcaac
ttgttctctatgatgcttggctctggaatgcctgaactgcaatcttttgatgatattgca
tatattcgaaaaacattagcattggataaaactgaacaagaggctttggaatacttcatg
aagcagatgaatgacgcacatcatggtggctggacaacaaaaatggactggatcttccat
acaataaagcatctttaa

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