KEGG   Xenopus tropicalis (western clawed frog): 100495530Help
Entry
100495530         CDS       T01011                                 

Gene name
plce1
Definition
(RefSeq) phospholipase C epsilon 1
  KO
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
xtr  Xenopus tropicalis (western clawed frog)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Calcium signaling pathway
Phosphatidylinositol signaling system
AGE-RAGE signaling pathway in diabetic complications
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:xtr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100495530 (plce1)
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    100495530 (plce1)
   04070 Phosphatidylinositol signaling system
    100495530 (plce1)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100495530 (plce1)
Enzymes [BR:xtr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100495530 (plce1)
Membrane trafficking [BR:xtr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100495530 (plce1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100495530 (plce1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Xenbase: 
Position
Un
AA seq 1741 aa AA seqDB search
MEEKREVFSHVVHIAKCCWNMGNYNAVMEFLAGLRTRKVLKMWQFMDQSDIETMRSLKDA
MAQHESSSEYRKVVNRALNIPGCKVVPFCGVFLKELCEVLDGAASIISLCPQYDAQSETL
EFVSDYNGQDNFLQRIGKDGLKNTEKESTVNSIMQTIRSCNRSLESEEGEDNLSDAGGIR
KSTVMDRTRFHSKKVYEPNRVLFIMGDLSDSESDIFEQSKEWDLHRREEQQKAFSHGTEL
IPWYVLSMRADVYQFLQQGVTVIRYDQETHISVRCFLQLQPDNSTLTWTKPTTTCLANTK
NKLGTVSSSAEIKFQFLANAGMNGLAEGFLDLFSVKAVYMGHPGIDMHTVCVQNKLCNMN
LEENGVTLLYGLHTTDNKLLHFVAPKYTARTLYDGLLELTKAVRKIKRFPDQRLQWLRKQ
YVSLYQEENRFEGPALAQAIELFGGRRWSTRNTSTGTLTKSTEKPNVQRNNTLGINTAKK
KKKVLMRGESGDAADDEMATRKTKSCKESRSRSGSDPPEIDEQEEQDLNIIAGYSPSQML
PSRRAHSMSTSGSPNLTPGPSIPLRPASSPILSNSNKPQSNTWSSSSWHGRVKGGMKGFQ
SFMVSDSNMNFTEFVELFKSFSVRSRKDLKDIFDVYAVACNRSGAESVPLYTNLTIDENV
VGVQPDLDLLTRNVSDLGLFIRSRQQLSENQRQISDAIAAASIVTNGTGVESTSLGIFGM
GILQFNDFLVNCQGEHYTYDEVLSIIQKFEPSISMRQQGLMSFEGFARFLMDKDNFASRN
DESQVNTEELQLPLSYYFIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKDVIEAIGRSAFITSEMPIVLSIENHCSLPQQRKMADIFKNV
FGEKLVTKFLFESDFSDDPMLPSPWQLRNKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QASNGSQMVSPSTNNEEEEDEEDEYDYDYESLSDADVLNASPAPNSQEDNILDDRSETKT
NSDKLQFEYNEEASKRIKKTDGSSINTKGKVYDMELGEEFYLPQNKKESRQIAPELSDLI
IYCQAVKFPGLTTLNPCGSGRGKERKSRKSIFGNNPGRTSPGEPTALAKTSGKGTNETRQ
SWEEPCSPPFNPSTSLSAIIRTPRCYHISSLNENAAKRLCRRYSQKLIQHTAYQLLRTYP
AATRIDSSNPHPLIFWLHGVQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVQWDRT
CPMYQLFSPLERDLENMEPAIYSLTIVSGQNVCPGNSSGSPCIEIDVLGMPVDSCHFRTK
PIHRNTLNPMWNEQFLFRIYFEDLVFLRFAVVENNSSAVTAQRIINLKALKRGNRHLQLR
NLHNEPLEVSTLFINSRRMEEIPNGNTLPASLFFSSEERKTPATFKATVHGIPGPEPFTV
FEISLGTTAKQLLDHILATIQGNEADITDYFLMEEKCFISKDKNECKKLPFQRVISPEED
ILQILNSWFPEEGYVGRIVLKTREENMNDKNVQEDKEEKEVTVSSDEETFFVQVHDVSPE
QPRTVIKALRFSTAQEVIQQALCKAKYSYSILSNPNPSDYVLLEEVIKEASNKKSSTSKT
IQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQAARDDKRKGLSIASELKKLAKSSRQSR
NFTLSPQIFLSEDACESPEPTKSKTQEKPSADNEVNVHPTCCRRSSAAWYFLLLKNWKLP
K
NT seq 5226 nt NT seq  +upstreamnt  +downstreamnt
atggaggagaaacgagaagttttctcacacgtcgttcacattgcaaagtgttgctggaac
atgggcaattacaacgctgtcatggaattcctggcaggcctcaggacaagaaaagttcta
aaaatgtggcaatttatggatcagtccgacattgaaacgatgcgcagcttgaaagatgca
atggcacagcatgaatcctcatccgagtacaggaaagtggtgaacagggccctaaatata
cctggctgtaaggtggttcctttttgtggggtctttctaaaggaactctgtgaagtcctt
gatggagcagcgagtatcatcagtctgtgtcctcagtacgatgctcagagtgaaacactg
gagtttgtttcagattacaatgggcaagacaactttctccagcgaatagggaaagatgga
ttaaagaacacagagaaagagtccactgtgaatagtatcatgcagacaattcgtagctgt
aaccgtagcttggaatctgaagaaggagaagacaatctcagcgatgccgggggtatcagg
aaaagcacagtgatggacagaactagatttcactccaagaaggtctatgagccaaaccgg
gttctgtttattatgggagatttatctgactctgaaagtgatatctttgaacaatcaaaa
gagtgggacttgcataggagggaagagcaacagaaggcattcagccatggaacagagcta
attccctggtatgtgttatccatgagagcagatgtctatcagtttcttcagcaaggagtg
actgtcatccgctatgaccaggagacacacatttctgttcgttgtttccttcaactccaa
ccagacaactccacattgacttggacaaaaccaaccacaacgtgtcttgcaaacactaaa
aataaattaggaactgtaagtagcagtgcggagattaaatttcagttccttgccaatgct
ggaatgaatggactggccgaaggattcttggacttattctctgtaaaggcagtttacatg
ggacatccgggaattgatatgcacactgtgtgtgttcaaaacaaactatgtaatatgaac
ctggaagaaaatggtgtcacattgctttatgggctgcacactactgacaacaagttgctg
cactttgtagctccgaaatacacagccaggacattgtatgatggactcctggagttaacc
aaagcagtaaggaagataaaacgctttcctgatcagagattacagtggttaaggaagcag
tatgttagtctctaccaggaggaaaacagatttgaaggaccagctttggcacaagctatt
gagctgtttggagggcgacgctggagtacgagaaacacgagcacagggaccttaaccaaa
agcacagagaaaccaaacgtgcagaggaataacactctcggcatcaacactgccaagaag
aagaagaaagtgcttatgaggggcgagagtggggatgcagccgatgatgagatggcaacc
cgcaaaacaaaaagctgcaaggaaagtcgcagtagaagtggctctgatcctccagaaatc
gatgagcaggaagagcaagatctgaatattattgctggatattcaccatctcaaatgctc
ccatcccgaagagctcattctatgtcgacttctggttctcccaacttgacacccgggcca
tctattccactgcgacctgcctcctctcctattttgtccaactcaaacaaaccccagtcc
aatacgtggagcagttcaagttggcatggaagagttaaaggtgggatgaaaggcttccaa
tcattcatggtttcggacagcaacatgaactttactgaatttgtagagcttttcaaatct
tttagcgtaagaagtcggaaagacctgaaggacatttttgatgtgtatgctgtggcctgc
aatcggtcaggtgcagaatcagtccctctctacactaatttgacaattgatgagaatgta
gttggagtccaacctgatttagatttattgaccaggaatgtgtccgacttgggtttattc
attcgcagcagacagcaactgtctgagaaccaaaggcaaatctcagatgccattgcagct
gccagcattgtaactaatggaactggagtagaaagcacatccctgggcatatttggaatg
ggaatactgcagtttaatgatttcctggtgaattgccagggtgaacattacacctatgat
gaagttcttagcattattcagaaatttgaaccaagtatcagtatgcgccagcaggggctg
atgtcatttgaaggatttgcaaggttcctgatggataaagacaattttgcatcaagaaat
gatgagtctcaggtaaacacagaagaacttcagctgcccctttcctactatttcattgag
tcttcacacaacacctaccttacagggcaccagctaaaaggagagtcttcagttgagctg
tacagccaggtccttttgcaggggtgccgaagtgttgaattagactgctgggatggagat
gacggcatgcctatcatttatcatggacatacactaactactaaaattccctttaaggat
gtcattgaagctattggccgaagtgcatttattacctctgaaatgccaatcgtactgtcc
atagaaaaccattgctccctaccacagcagcgtaaaatggcagatatatttaagaatgtc
tttggtgaaaaactggtgacaaagttcctgtttgaaagtgacttttcagatgatccgatg
ttgccttctccatggcaattgagaaataaagtgcttctgaaaaataaaaagctgaaggca
catcaaaccccggtggatatactgaagcagaaggcacatcagctggctagcatgcaagca
caagcaagcaatggtagccaaatggtaagccctagcacaaacaatgaagaagaagaagat
gaagaagatgaatatgattatgactatgagtctctgtcagatgccgatgtccttaatgct
tcccctgctcctaacagccaggaagataatattcttgatgaccgatctgaaactaaaacc
aacagcgacaaactgcaatttgaatataatgaggaagcttcaaagcgaatcaaaaagaca
gatggcagcagtattaacactaaaggaaaggtctatgacatggagttgggtgaggaattc
tatcttccacaaaacaaaaaagagagcaggcaaattgcacctgaattgtcagaccttatt
atctattgccaagctgtcaaattcccaggccttacaacattaaacccatgtggatctggc
agagggaaggaaagaaaaagcaggaagtccatttttggcaacaaccctggcagaacaagt
cctggggaaccaacagcacttgccaaaacatctggaaaaggtacaaatgaaacacggcag
agctgggaagagccatgttctcctccctttaaccccagcacttccctcagtgcaataatc
aggacacccaggtgctaccatatctcttccctaaatgagaacgcagccaagcgcttgtgc
cgaaggtattctcagaaactcattcaacataccgcatatcaactgctccgaacatatccc
gccgccactcggatagactcttccaacccacatcctcttattttctggcttcatggtgta
cagttggttgctctaaactaccaaactgatgatctccccttacatctaaacgccgccatg
tttgaagcaaatggtggttgcggatatgtgttaaagccccccgtgcagtgggataggacc
tgcccaatgtaccaattattctcaccattagaacgagatttagaaaatatggaaccagca
atatattctttgacgatagtctctgggcaaaatgtgtgtccaggtaacagctcaggcagc
ccctgcattgaaattgatgtcttgggtatgccagtagacagctgccattttcggaccaaa
ccaatccatcgcaataccttaaatcccatgtggaatgaacaattcttattccgaatatac
tttgaggatcttgtgtttcttcggtttgctgtggtggaaaacaacagttctgctgtaact
gcccaaagaataattaatcttaaagctttaaagagaggtaacagacaccttcagctaaga
aatttacataatgagcccttagaggtttctaccttatttataaatagcaggagaatggaa
gaaatccctaatggaaataccttacccgcctccttgtttttcagctcagaagaaagaaag
actccagccacatttaaagctacagtacatgggattcctgggccagaaccatttacagtg
tttgaaatcagtcttgggacaactgcaaagcaacttcttgatcatattttggctactata
caaggcaatgaagcagacatcactgactattttttgatggaggaaaaatgctttatatct
aaagacaaaaatgaatgcaagaaattgccgttccagagagtgattagcccagaagaggat
atcctgcaaattttgaatagctggttcccagaagaaggctacgtggggagaattgttctt
aaaacacgagaggagaacatgaatgacaaaaatgttcaagaggacaaagaagaaaaagag
gtgaccgtgagctccgatgaggagactttctttgtccaggtccatgatgtttctcctgaa
cagccaagaacggttatcaaagctttacgattcagtacagcgcaggaagttatccagcag
gctttatgcaaggctaaatactcatacagcatcctgagcaaccctaatcctagtgattat
gtgcttctggaggaagtcatcaaagaagcttcaaataagaagtcttctacctccaaaaca
attcagagggttctcttggatcaagagtgtgtattccaggcacagagcaagtggaaggga
gcagggaaattcattcttaaactgaaggaacaagtccaggcggcaagagacgacaagcgc
aaaggtctgtctatagccagtgaactgaagaagctagcaaagtccagccggcaatctcgg
aacttcactttgtcacctcagatatttttatcagaagatgcctgtgaaagccctgaacct
acaaaaagcaaaacgcaggaaaagccttcggcagataatgaagtaaatgtgcatccaacc
tgctgcaggaggtcttctgctgcctggtactttctgttgctgaagaactggaagctgcca
aaatga

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