KEGG   Xenopus tropicalis (western clawed frog): 493420Help
Entry
493420            CDS       T01011                                 

Gene name
map2k1, map2k2, mapkk1, mek1, mkk1, prkmk1
Definition
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)
Orthology
K04368  
mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
xtr  Xenopus tropicalis (western clawed frog)
Pathway
MAPK signaling pathway
ErbB signaling pathway
FoxO signaling pathway
Oocyte meiosis
Vascular smooth muscle contraction
Dorso-ventral axis formation
VEGF signaling pathway
Focal adhesion
Gap junction
Toll-like receptor signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Melanogenesis
Brite
KEGG Orthology (KO) [BR:xtr00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    493420 (map2k1)
   04012 ErbB signaling pathway
    493420 (map2k1)
   04370 VEGF signaling pathway
    493420 (map2k1)
   04068 FoxO signaling pathway
    493420 (map2k1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    493420 (map2k1)
  Cell growth and death
   04114 Oocyte meiosis
    493420 (map2k1)
  Cell communication
   04510 Focal adhesion
    493420 (map2k1)
   04540 Gap junction
    493420 (map2k1)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    493420 (map2k1)
  Endocrine system
   04910 Insulin signaling pathway
    493420 (map2k1)
   04912 GnRH signaling pathway
    493420 (map2k1)
   04914 Progesterone-mediated oocyte maturation
    493420 (map2k1)
   04916 Melanogenesis
    493420 (map2k1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    493420 (map2k1)
  Development
   04320 Dorso-ventral axis formation
    493420 (map2k1)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     493420 (map2k1)
Protein kinases [BR:xtr01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   493420 (map2k1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Xenbase: 
UniProt: 
Position
Un
AA seq 395 aa AA seqDB search
MPKKKPTPIQLNPNPEGTAVNGTPTAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKVSELGAGNGGVVFKVSHKPTSLIMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGKIPEKILGKVSIAVIKGLTYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAIGRYPIPPPDAKELELIFGCSVEGDPASSELAPRPRPPGRPIS
SYGPDSRPPMAIFELLDYIVNEPPPKLPSGVFGAEFQDFVNKCLVKNPAERADLKQLMVH
SFIKQSELEEVDFAGWLCSTMGLKQPSTPTHAAGV
NT seq 1188 nt NT seq  +upstreamnt  +downstreamnt
atgcctaagaagaagcctacgcccatacagctgaaccccaaccctgaggggactgctgtg
aacggaacccctacagccgagacaaaccttgaagctctgcagaaaaagttggaagagctg
gagctggatgagcagcagaggaagcgtctagaggcctttctcacccagaagcagaaagtt
ggggagctgaaggatgatgactttgagaaagtgtcggagcttggagcaggcaatggagga
gtggtgtttaaggtgtcccacaagccgactagcttgattatggccaggaagttaattcat
ctggagataaagcctgcaatcagaaatcagattatccgagagttgcaggttctgcatgaa
tgtaactccccatacattgtggggttctatggggccttctacagtgacggagagatcagc
atttgtatggaacacatggatggaggctcccttgatcaggttttgaagaaagctggcaaa
atccctgagaaaattttgggaaaagtcagcattgcagtgataaaaggtctaacctacctg
agagagaagcataagataatgcacagagatgtgaaaccttctaacatcctagtcaactct
aggggagagataaaactctgcgactttggagtcagcgggcagctaatagactccatggca
aattcctttgttgggacaagatcctatatgtcaccggagcggctacagggcactcattat
tctgtgcaatctgacatctggagcatggggctgtcacttgtggaaatggccataggaagg
tatcccattccaccacctgatgccaaagaactggaacttatctttgggtgttctgtagaa
ggggacccggcatcttctgaactggcgcctcgcccccggccacctggacgtccaatcagt
tcttatggtcctgatagtcgaccaccaatggccatttttgagcttctggattatatagtg
aacgagccacctccaaaattgcccagtggagtatttggagctgagttccaggactttgtg
aataaatgtcttgtgaagaatccagcagagagagcagatcttaaacagctaatggttcac
agcttcattaagcagtcagagttggaggaggtggattttgctggatggctttgttccact
atgggtcttaaacagcccagtaccccaacccatgccgctggagtgtga

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