KEGG   Xenopus tropicalis (western clawed frog): 780390Help
Entry
780390            CDS       T01011                                 

Gene name
pik3cb, p110-beta, pi3k, pi3k92e, pi3kbeta, pik3c1
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta (EC:2.7.1.153)
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
xtr  Xenopus tropicalis (western clawed frog)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:xtr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    780390 (pik3cb)
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    780390 (pik3cb)
   04370 VEGF signaling pathway
    780390 (pik3cb)
   04630 Jak-STAT signaling pathway
    780390 (pik3cb)
   04068 FoxO signaling pathway
    780390 (pik3cb)
   04070 Phosphatidylinositol signaling system
    780390 (pik3cb)
   04150 mTOR signaling pathway
    780390 (pik3cb)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    780390 (pik3cb)
  Cell growth and death
   04210 Apoptosis
    780390 (pik3cb)
  Cellular commiunity
   04510 Focal adhesion
    780390 (pik3cb)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    780390 (pik3cb)
  Endocrine system
   04910 Insulin signaling pathway
    780390 (pik3cb)
   04914 Progesterone-mediated oocyte maturation
    780390 (pik3cb)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    780390 (pik3cb)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     780390 (pik3cb)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Xenbase: 
UniProt: 
Position
Un
AA seq 1065 aa AA seqDB search
MPPIMDHMDIWTADTPLPPDICVDVLLPTGIYVQMDVPRDASISHIKQLLWKHAQSYPLF
HLLLEIDSYMFQCVNHNAVHEELEDETQRLCDVRPFLPVLKLVSRSCNPAEKLDSKIGVL
IGKGLQEFDALKDNEVMEFRSKMRSISEAKIQSLLGLTWVEWLKRTFPPELEPSIQDNIQ
GKLYGGNIVVAIHFENCQDVFSFQVSPNMVPVKVNELAIRKRLTIHGREAEEVDPEDFVL
QVNGRLEFVFGDHPLIQFQYIRNCVMNKALPHLTLVECCNIKKLFDQEMSEIEHAVRRKS
SMHPALPMPLPPKKRGASMKTLNMRDIVWNIVQPYKIILSKGSRLNTEDSVLVRAGLFHG
TELLCKPTMTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQ
TIKKSGKMHFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPYTE
NTTTLHIKFHDYSKEPISYPPFDKILEKAAEIARNSDSLSTSGRGGKKLNIELKEIMERD
PLCQLSENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRD
ALELLDFNYPDQYVREYAVNCLKPMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRAL
DNRRIGQFLFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGL
IKLNAVKLSKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKP
LWIVYNNRGFGSDSLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATG
DRCGFIEVVSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECHSGDDLERAIEEFTLSC
AGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFI
HVIQQGKPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVK
DSLALGKKEEDALKQFRQKFDEALKESWTTKVNWMAHTMRKDYKA
NT seq 3198 nt NT seq  +upstreamnt  +downstreamnt
atgccccctataatggaccacatggacatctggacagcagatacaccgcttcctccagat
atctgtgtggacgtcttgcttcccactggtatatatgtgcagatggacgtcccaagggat
gcatccatatctcatattaaacagctcctgtggaagcatgcacagagctaccctctgttt
cacctccttctggagattgactcctatatgttccagtgcgttaatcataatgctgttcac
gaagagctagaggatgagactcaacgtttgtgtgatgttcgccccttcctgcctgtcctg
aaattggtatcccgaagctgcaatcccgcagagaagttagattccaagataggggttctg
ataggaaaaggtcttcaggaatttgatgccctaaaagacaacgaggtcatggaattccgc
agcaagatgagaagtatcagtgaggcgaagatccaatccctgcttggcctaacatgggta
gagtggctaaagcgtacattccccccagaactagaaccatccatacaggataacatccaa
ggcaagctctatggtggcaacattgtagtggccattcattttgagaactgccaggatgta
ttcagttttcaagtgtctccgaacatggtccctgtgaaagtaaatgagcttgctattcga
aagcgcctgactatccatggcagagaagcggaagaggtagatcctgaggattttgtgctg
caggtcaacggaaggctggaatttgttttcggggatcaccctttaattcagtttcagtac
atcagaaactgtgtaatgaacaaggctttgccacatctaacactggttgagtgttgcaac
atcaaaaaactgtttgaccaagagatgagtgagattgaacatgctgtgaggagaaagtca
tccatgcacccagcgcttccaatgcccttgcctccaaagaaacggggtgcatcaatgaag
actctgaatatgcgggatattgtgtggaatattgttcagccatacaagatcatactgtcc
aaagggagtagactgaacacagaggacagtgttttggtccgggctggcctttttcatggc
accgaactattgtgtaaacccacaatgactccggaagtgcaaggaaagaatgatcatgtt
tggaacgagacactggaatttgaaatcaatgtctgtgaccttccacgaatggcacgtctc
tgttttgctatatacgctgttctggacaagcctaggaacaagaacaaaaccaaatatcag
acaatcaagaagtctggcaaaatgcacttccctgtagcctgggtgaacaccatggtgttt
gactacaaagggcagctgagatctggggaccatgtattgcactgctggtcgtcattccct
gatgaacttgaagaaatgctaaatcccatgggaacagttcgaaccaatccttacactgag
aataccacaactctacacataaagtttcacgactactccaaagaacccatttcttatcca
ccatttgataagatacttgaaaaagctgctgaaattgcacggaacagtgacagcctgtct
acgtcgggtcgaggtgggaaaaagcttaatattgagctcaaggagatcatggaacgggac
cctttgtgccagttatctgagaatgagaaggatctgatctggaccttgcggtacgactgt
agagagaactttcctggctctctgcccaagcttctcttgtctgtcaagtggaacaagctg
gaggatgtggcacagcttcaagccctactccaaatctggtccaaacttcccccaagggat
gccctggaattgcttgactttaactatcctgaccagtatgtgagagaatatgcagtcaac
tgtcttaaaccaatgagtgatgaggagctctcccagtaccttctgcagcttgtgcaggtt
ctgaagtatgagccgtttctggactgtgccctgtcacgcttcctcctacagagagccctg
gataaccgcaggataggacagttcctcttctggcacctgaggtctgaggtccataaccct
gctgtctctgtgcaatttggcctgctgctggaagcatactgccgagggagcgtggcccac
atgaaagtgctgtctagacaggtggaggctctgaataaactgcgcacgttaaatggacta
atcaaactgaatgctgtgaagctgagcaaggtcaaaaacaaagacaatatgcatacatgc
ctgagggagaacgcctacaaggaggcactgatgcacattcagtcgcccctcaaccccagc
atcaccctttctgaacttgttgtagagaagtgcaagtacatggattctaagatgaagccc
ctctggattgtgtacaacaaccgtggatttggcagcgactctcttggaatcatctttaaa
aatggggatgacctacgtcaggacatgctagcacttcagctgctgcggcttatggacatg
ttgtggaaggaggctgggttggacctgaggatagtgccttatggctgcctagcaactgga
gatcgctgcggttttatagaggtggtgtccgctgcagagactattgcagacatccagctg
gacagcagcaaccttgcggctgcagccgctttcaacaaagatgctctgttaaattggatc
aaggaatgtcattctggtgatgacctagagcgagctattgaggaattcaccttgtcctgt
gctggctactgtgtagctacttacgttcttggaattggtgaccgccacaatgacaacatc
atggttaggaagaccgggcagctttttcacattgattttggacacattctggggaacttc
aagtccaagtttaaaattaagagggagcgtgggccctttattcttacgtacgacttcatt
cacgtgatccaacagggaaaaccagggaacacagagaaatttggcaggtttcggcagtgc
tgcgaggatgcctacttgatcctacgcagaaatgggaacctcatcattactctgtttgca
ctaatgctgacagctggactccctgagctgagttctgttaaagatatccagtatgtcaag
gactcccttgccctgggcaagaaagaggaggacgcacttaagcaattccgccagaagttt
gatgaggccctaaaagaaagctggacaaccaaagttaactggatggcccacacaatgcgc
aaggattacaaggcttag

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