KEGG   Yersinia pestis 91001 (biovar Microtus): YP_0118
Entry
YP_0118           CDS       T00165                                 
Symbol
metL
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase II
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
ypm  Yersinia pestis 91001 (biovar Microtus)
Pathway
ypm00260  Glycine, serine and threonine metabolism
ypm00261  Monobactam biosynthesis
ypm00270  Cysteine and methionine metabolism
ypm00300  Lysine biosynthesis
ypm01100  Metabolic pathways
ypm01110  Biosynthesis of secondary metabolites
ypm01120  Microbial metabolism in diverse environments
ypm01230  Biosynthesis of amino acids
Module
ypm_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ypm_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
ypm_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:ypm00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    YP_0118 (metL)
   00270 Cysteine and methionine metabolism
    YP_0118 (metL)
   00300 Lysine biosynthesis
    YP_0118 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    YP_0118 (metL)
Enzymes [BR:ypm01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     YP_0118 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     YP_0118 (metL)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3
Other DBs
NCBI-ProteinID: AAS60397
UniProt: A0A2S9PC83
Position
124135..126570
AA seq 811 aa
MNATAVAAAATGRQLHKFGGSSLADVKCYLRVANIMANYSHPGDLMVVSAAGSTTNQLIS
WLKLSQNDRLSAHQVQQSLRRYQHDLINGLLPPEMAEPLISEFIHDLERLAGLLDNKIDD
VIYAEVVGHGEIWSARLMSALLNKLDMDAVWLDARRFLRAERAAQPQIDESRSYPLLQQL
MAQHPHQRLVVTGFISRNEAGETVLLGRNGSDYSATQVGALAGAERVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGLGAKIVTSHDDVCLIELQIASHHDFSLAQKEIDLLLKRAQIKPLATGIHPDRNL
LQLCYTSEVVNSALRVLEDAALPGKLSLREGLALVALVGAGVSKNPLHSHRFYQQLKDQP
VEFVWQAEDGISMVAVLRLGPTEHLIQGLHQSLFRAEKRIGLMLFGKGNIGARWLELFAR
EQKSLSARSGFEFVLAGVVDSRRSLLSYDGLDASRTLAFYNDEAKEQDEESLFLWMRAHP
FDDLVVLDVTASPSLAEQYLDFASYGFHVISANKLAGASSSNNYRQIRDAFAKTGRHWLY
NATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGAESGSVDQFFENGEALN
QQMIQRLEAAKEMGLVLRYVARFDANGKARVGVEAVRTDHPLASLLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLSQLL
NT seq 2436 nt   +upstreamnt  +downstreamnt
atgaatgcaacagcggtagcagcggcggcaacgggccgtcaactgcataaatttggtggc
agtagccttgcggatgtgaagtgttatctacgggtggctaatattatggccaactacagt
caccccggcgatctcatggtggtgtctgctgccgggagcacgacaaaccagttgatcagt
tggttgaaactcagtcaaaacgaccgtctttctgctcatcaggtacagcaaagtctgcgt
cgttatcaacacgatctgatcaatggcttattgcctccagaaatggcagagccattaatc
agtgagtttattcatgatttagagcgcctggcgggcttgctggataataaaattgatgat
gtgatttatgctgaagtggttggtcatggtgaaatttggtcagcccgcttgatgtctgcg
ctactgaataagttggatatggatgccgtctggcttgacgcccgccgtttcctacgtgca
gagcgtgcagcgcaaccacaaattgatgaaagccgctcttatccgttactgcaacaatta
atggcccaacaccctcaccagcgtttggtggtgactggttttatctcgcgcaatgaggcg
ggtgaaacggtcttgcttggccgtaatggcagtgactattcggcgacgcaggtcggggca
ttggccggggccgagcgtgtcaccatctggagtgatgttgccggggtgtacagtgccgat
ccacgtaaagtgaaggacgcttgcctgctaccattattgcggttggatgaagccagtgaa
ctggcccgcctggcagcaccggtgttacatacccgcacattacaaccggtttctggtagt
gacatcgatttgcaattacgttgcagttatcagccggagcaggggtcaacccgtattgaa
cgtgtgctggcttcgggattgggtgccaagatagtgaccagccacgatgatgtttgcctg
attgaattgcagattgccagtcaccatgatttctcgttggcgcagaaagagatcgatcta
ctgctcaaacgtgcgcaaatcaaaccactggcgaccggtattcacccagatcgtaacctg
ctgcaactttgctatacctcagaagtggttaacagcgccttacgggtgttggaagatgcc
gctctgccggggaaactctctctgcgcgaagggctggcattggtcgcactggtgggggcg
ggggtgagcaagaacccacttcacagtcaccgtttctaccaacaactgaaagatcagcca
gttgagtttgtctggcaggccgaagacggtatcagtatggtggccgtcctgcgtcttggg
ccgactgagcacctgattcaagggttgcaccagtcgttgttccgggcggaaaaacgtatt
ggtctgatgctgtttggcaaaggcaacattggtgctcgctggttggagctgtttgcccgt
gagcagaaaagtctttcggcccgcagtggttttgaatttgtgctagccggggtggtcgat
agccgccgtagtctgctgagttacgatggtttggatgccagccggacgctggcattttac
aacgatgaagccaaagaacaggatgaagaatccctgttcttgtggatgcgtgcccacccg
tttgacgacctggtggtgttggatgtgaccgccagcccgtcacttgcagaacaatatctg
gattttgccagttatggtttccacgttatcagcgcgaacaaattagcgggggcttcaagc
agcaataattaccgccaaatccgcgatgcgtttgcgaaaactggccgccactggttgtat
aacgccacggtaggcgcggggttaccggttaaccatacggtgcgcgatctgcgtgacagt
ggcgacagtattttagcgatcagcggtattttctctggcacgctgtcttggttattcctg
caatttgatggctcagtaccttttaccgagctggtagaccaagcctggcagcaaggtttg
accgagcctgatccaagggttgatctctctggtcaggatgtaatgcgtaagttggtgatt
ttagcccgtgaagcgggttacgacatcgaaccgaatcaggtgcgggtggagtcgttggtg
cctgctggcgcagagagtgggtcggttgatcaattctttgaaaacggcgaggcattaaat
cagcaaatgattcagcgtttagaagccgcgaaggagatgggcttggtattacgctacgtg
gcacgctttgatgctaatggtaaagcgcgggtgggcgttgaagcggtacgtaccgatcat
ccgttggcttctttgctaccgtgcgataatgtttttgctattgagagccgctggtatcgc
gataatccgttggtgattcgcggcccaggcgctggccgtgatgtgaccgctggggcgatt
caatctgatttaaaccgcctatcacaactgttgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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