KEGG T01088: 541707

Zea mays (maize): 541707

Entry

541707 CDS T01088

Gene name

DRTS, DHFR-TS

Definition

bifunctional dihydrofolate reductase-thymidylate synthase (EC:1.5.1.3 2.1.1.45)

Orthology

K13998

dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]

Organism

zma Zea mays (maize)

Pathway

zma00240	Pyrimidine metabolism
zma00670	One carbon pool by folate
zma00790	Folate biosynthesis
zma01100	Metabolic pathways

Module

zma_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Class

Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH:zma00240]
Metabolism; Metabolism of cofactors and vitamins; Folate biosynthesis [PATH:zma00790]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:zma00670]

SSDB

Motif

Pfam:

Thymidylat_synt DHFR_1

Other DBs

NCBI-GI:

162464289

NCBI-GeneID:

541707

UniProt:

O81395

Position

2; 4

AA seq 521 aa
MAAVLANGDSQGRPQRNYQVVVAGTRDMGIGKDGVLPWKLPGDLKFFKELTLTTSDPVKK
NAVIMGRKTWESIPVKSRPLPGRLNVILTRSGSFDFATVENVVICGSMESALELLASTPY
CLSIEKVFVIGGGQVLREYLKGPACEAIHLTDIQSSIECDTFIPPVDFSVFQPWYSSFPV
IESNIRHSFVSFVRVRKSVAETHESNGKESTEVDTKNDKFETENFSFLPKMVYDRHEEYQ
YLNLVEDIIRSGAQKNDRTGTGTLSKFGCQMRFNLRKNFPLLTTKRVFWRGVVEELLWFI
SGSTNAKVLQEKGIHIWDGNASREYLNSVGLAHREEGDLGPIYGFQWRHFGAEYTDMHAD
YTGKGFDQLMDVIDKIKNDPEDRRIILSAWNPSDLKKMALPPCHMFAQFYVENGELSCQM
YQRSADMGLGVPFNIASYSLLTYMIAQVCDLSPGDFVHVIGDAHVYRNHVRALEEQIQKM
PKPFPILKINPSKKDIDSFMASDFKLVGYDPHQKIEMKMAV

NT seq 1566 nt +upstreamnt +downstreamnt
atggccgcagttctagccaatggtgattcacagggtcgtcctcagaggaactatcaagtt
gttgttgctggcactcgtgacatgggcattgggaaggatggggtcttgccatggaagctt
cctggtgatcttaaattctttaaagagcttacactaactacatctgatcctgtcaaaaag
aatgcagttataatgggaaggaaaacatgggagagcattccggttaagtcaaggccattg
cctggtcgtttgaatgtcatacttactcgatctggtagttttgattttgcaacagtagag
aatgttgttatctgtggaagtatggagtctgccttagaactgctagcatcaactccatat
tgcttatcaattgagaaagtgtttgttataggaggcgggcaggtactgagagaatatctt
aaaggacctgcatgtgaggctatccatctaactgacattcagtcaagcattgagtgtgac
actttcatccctccggttgacttctcagtgttccagccatggtattcatctttcccggtg
atagagagcaacattaggcattcgtttgtgtcttttgttcgtgttagaaagtcagtggca
gaaactcatgagtcaaatggcaaggaatcaaccgaggttgataccaagaatgacaaattt
gaaacagagaatttctcttttctccccaagatggtatatgaccgccatgaggagtaccaa
tatctcaatcttgttgaagatattataaggtctggtgctcagaaaaacgacaggacagga
actggaacattgtcaaaatttgggtgtcagatgcggttcaacttaaggaaaaattttcct
ctgctgacaacaaagagggtattttggcgtggtgttgtcgaagaactcctttggttcatc
agtggctcaacaaatgcaaaggttttgcaagagaagggtattcatatctgggatggcaat
gcttcaagagagtatctcaacagtgttggcttggcacacagggaggaaggtgatttaggt
ccaatttatggatttcagtggcgtcactttggtgctgaatacactgacatgcatgctgac
tatacgggaaaaggttttgatcagctaatggatgtgattgacaagatcaagaatgatcct
gaggaccgtcgaataattttgtcggcgtggaatccttcagatctcaagaagatggctctt
cctccttgccacatgtttgcacaattctatgtggaaaatggggagctatcttgccagatg
tatcaacgctctgcagacatggggcttggtgttccattcaacatcgcatcatattctctc
ctgacatacatgattgctcaagtttgtgatctttctcctggagattttgtccatgttata
ggggatgcccatgtctatagaaaccatgttcgagcactggaggagcaaattcagaagatg
cctaaaccatttccaattttgaagataaatccttcaaaaaaggatatagattcttttatg
gcatcagacttcaagctggttggctatgatccccaccagaagatagagatgaaaatggca
gtgtaa

All links

Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UniGene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (39)   

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