| C04931 |
Argatroban; (2R,4R)-4-Methyl-1[Nalpha-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperadinecarboxylic acid |
(P) unclassified |
| C06174 |
Codeine; (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol |
(P) unclassified |
| C06807 |
Acetophenazine |
(P) unclassified |
| C07005 |
Flunisolide; Flunisolide anhydrous |
(P) unclassified |
| C07051 |
Indinavir |
(CI,P) unclassified |
| C07521 |
Thiopental |
(P) unclassified |
| D00066 |
Progesterone (JP18/USP/INN); Crinone (TN); Prometrium (TN) |
(P) Enzyme: CYP3A4 CYP2C19 |
| D00067 |
Estrone (JAN/USP/INN); Estrone (TN) |
(P) Enzyme: CYP3A4 |
| D00105 |
Estradiol (JAN/USP/INN); Climara (TN); Divigel (TN); Estrace (TN); Estraderm (TN); Estrasorb (TN); Estring (TN); Estrogel (TN); Innofem (TN); Vagifem (TN); Vivelle (TN) |
(P) Enzyme: CYP3A4 |
| D00107 |
Tacrolimus (USP/INN); Tacrolimus hydrate (JP18); Prograf (TN); Protopic (TN) |
(P) Enzyme: CYP3A4 |
| D00136 |
Haloperidol (JP18/USP/INN); Haldol (TN) |
(P) Enzyme: CYP3A4 |
| D00140 |
Erythromycin (JP18/USP/INN); Akne-mycin (TN); Eryc (TN); Erygel (TN); Pce (TN); Staticin (TN); T-stat (TN) |
(P) unclassified |
| D00181 |
Argatroban (USP); Argatroban hydrate (JP18); Novastan (TN) |
(P) Enzyme: CYP3A4 |
| D00184 |
Cyclosporine (USP); Ciclosporin (JP18); Gengraf (TN); Neoral (TN); Restasis (TN); Sandimmune (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00186 |
Ciprofloxacin (JP18/USP/INN); Cipro (TN); Otiprio (TN) |
(P) unclassified |
| D00195 |
Codeine (USP); Codeine hydrate |
(P) unclassified |
| D00210 |
Norfloxacin (JP18/USP/INN); Noroxin (TN) |
(P) unclassified |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(P) CYP induction: CYP3A4 |
| D00236 |
Atovaquone (JAN/USP/INN); Mepron (TN) |
(P) unclassified |
| D00241 |
Baclofen (JP18/USP/INN); Kemstro (TN); Lioresal (TN) |
(P) unclassified |
| D00246 |
Budesonide (JP18/USP/INN); Entocort EC (TN); Pulmicort (TN); Rhinocort (TN); Uceris (TN) |
(P) Enzyme: CYP3A4 |
| D00252 |
Carbamazepine (JP18/USP/INN); Equetro (TN); Tegretol (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00255 |
Carvedilol (JP18/USP/INN); Artist (TN); Coreg (TN) |
(P) Enzyme: CYP3A4 |
| D00270 |
Chlorpromazine (USP/INN); Thorazine (TN) |
(P) unclassified |
| D00276 |
Clarithromycin (JP18/USP/INN); Biaxin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00282 |
Clotrimazole (JP18/USP/INN); Lotrimin (TN); Mycelex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00283 |
Clozapine (JAN/USP/INN); Clozaril (TN) |
(P) Enzyme: CYP3A4 |
| D00287 |
Cyclophosphamide (USP); Cyclophosphamide hydrate (JP18); Cytoxan (TN); Neosar (TN) |
(P) Enzyme: CYP3A4 |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00295 |
Cimetidine (JP18/USP/INN); Tagamet (TN) |
(P) CYP inhibition: CYP3A4 |
| D00303 |
Disopyramide (JP18/USAN/INN); Rythmodan P (TN) |
(P) Enzyme: CYP3A4 |
| D00312 |
Estrone sodium sulfate; Sodium estrone sulfate |
(P) Enzyme: CYP3A4 |
| D00319 |
Felodipine (JP18/USP/INN); Plendil (TN) |
(P) Enzyme: CYP3A4 |
| D00320 |
Fentanyl (JAN/USP/INN); Duragesic (TN); Subsys (TN) |
(P) Enzyme: CYP3A4 |
| D00321 |
Finasteride (JAN/USP/INN); Propecia (TN); Proscar (TN) |
(P) Enzyme: CYP3A4 |
| D00322 |
Fluconazole (JP18/USP/INN); Diflucan (TN) |
(P) CYP inhibition: CYP2C19 CYP3A4 |
| D00324 |
Flunisolide (JAN/USP); Aerospan (TN); Nasalide (TN) |
(P) Enzyme: CYP3A4 |
| D00326 |
Fluoxetine (USAN/INN); Fluoxetine (TN) |
(P) CYP inhibition: CYP2C19 |
| D00336 |
Glyburide (USP); Glibenclamide (JP18/INN); Diabeta (TN); Glynase (TN); Micronase (TN) |
(P) Enzyme: CYP3A4 |
| D00343 |
Ifosfamide (JAN/USP/INN); Ifex (TN) |
(P) Enzyme: CYP3A4 |
| D00346 |
Isoniazid (JP18/USP/INN); Laniazid (TN) |
(P) unclassified |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00351 |
Ketoconazole (JP18/USP); Nizoral (TN); Xolegel (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00355 |
Lansoprazole (JP18/USP/INN); Prevacid (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP2C19 |
| D00358 |
Lidocaine (JP18/USP/INN); Dentipatch (TN); Xylocaine (TN) |
(P) Enzyme: CYP3A4 |
| D00359 |
Lovastatin (USP/INN); MK-803; ML-530B; Mevacor (TN) |
(P) Enzyme: CYP3A4 |
| D00364 |
Loratadine (JAN/USP/INN); Claritin (TN) |
(P) Enzyme: CYP3A4 |
| D00373 |
Thioridazine (USP/INN); Mellaril-S (TN) |
(P) unclassified |
| D00387 |
Triazolam (JP18/USP/INN); Halcion (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00390 |
Triflupromazine (USP/INN); Vesprin (TN) |
(P) unclassified |
| D00403 |
Methotrimeprazine (USP); Levomepromazine (USAN/INN); Levoprome (TN) |
(P) unclassified |
| D00407 |
Methylprednisolone (JP18/USP/INN); Medrol (TN) |
(P) Enzyme: CYP3A4 |
| D00416 |
Miconazole (JP18/USP/INN); Monistat (TN); Oravig (TN) |
(P) unclassified |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00422 |
Ranitidine (USAN/INN); Ranitidine (TN) |
(P) unclassified |
| D00424 |
Rifabutin (JAN/USP/INN); Mycobutin (TN) |
(P) Enzyme: CYP3A4 |
| D00426 |
Risperidone (JP18/USP/INN); Risperdal (TN) |
(P) Enzyme: CYP3A4 |
| D00427 |
Ritonavir (JAN/USP/INN); Norvir (TN) |
(CI,P) CYP induction: CYP2C19 |
| D00429 |
Saquinavir (JAN/USP/INN); Fortovase (TN) |
(CI,P) Enzyme: CYP3A4 |
| D00430 |
Secobarbital (USP/INN); Seconal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00434 |
Simvastatin (JP18/USP/INN); MK-733; Zocor (TN) |
(P) Enzyme: CYP3A4 |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 |
| D00437 |
Nifedipine (JP18/USP/INN); Adalat (TN); Afeditab CR (TN); Procardia (TN) |
(P) Enzyme: CYP3A4 |
| D00438 |
Nimodipine (USP/INN); Nimotop (TN); Nymalize (TN) |
(P) Enzyme: CYP3A4 |
| D00453 |
Ofloxacin (JP18/USP/INN); Floxin (TN) |
(P) Enzyme: CYP3A4 |
| D00454 |
Olanzapine (JAN/USP/INN); Zyprexa (TN) |
(P) unclassified |
| D00455 |
Omeprazole (JP18/USP/INN); Prilosec (TN) |
(P) Enzyme: CYP2C19 |
| D00456 |
Ondansetron (JAN/USP/INN); Zofran ODT (TN) |
(P) Enzyme: CYP3A4 |
| D00457 |
Quazepam (JAN/USP/INN); Doral (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00458 |
Quetiapine fumarate (JP18/USP); Seroquel (TN) |
(P) Enzyme: CYP3A4 |
| D00465 |
Oxybutynin (USAN/INN); Anturol (TN); Oxytrol (TN) |
(P) Enzyme: CYP3A4 |
| D00471 |
Praziquantel (JAN/USP/INN); Biltricide (TN) |
(P) Enzyme: CYP3A4 |
| D00474 |
Primidone (JP18/USP/INN); Mysoline (TN) |
(P) unclassified |
| D00479 |
Prochlorperazine maleate (JP18/USP); Compazine (TN) |
(P) unclassified |
| D00482 |
Propoxyphene hydrochloride (USAN); Dextropropoxyphene hydrochloride; Darvon (TN) |
(P) unclassified |
| D00491 |
Paclitaxel (JAN/USP/INN); Abraxane (TN); Taxol (TN) |
(P) Enzyme: CYP3A4 |
| D00493 |
Prochlorperazine (JAN/USP/INN); Compro (TN) |
(P) unclassified |
| D00498 |
Pentazocine (JP18/USP/INN); Fortral (TN) |
(P) unclassified |
| D00499 |
Pentobarbital (USP/INN); Nembutal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00500 |
Pentobarbital sodium (JAN/USP); Nembutal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00503 |
Perphenazine (JP18/USP/INN); Trilafon (TN) |
(P) unclassified |
| D00505 |
Phenelzine sulfate (USP); Nardil (TN) |
(P) unclassified |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) unclassified |
| D00528 |
Caffeine (USP); Anhydrous caffeine (JP18); Anhydrous caffeine (TN); Respia (TN) |
(P) unclassified |
| D00529 |
Montelukast sodium (JP18/USP); Singulair (TN) |
(P) Enzyme: CYP3A4 |
| D00530 |
Zaleplon (JAN/USP/INN); Sonata (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 |
| D00537 |
Topiramate (JAN/USP/INN); Topamax (TN); Trokendi xr (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00539 |
Ethosuximide (JP18/USP/INN); Zarontin (TN) |
(P) Enzyme: CYP3A4 |
| D00542 |
Halothane (JP18/USP/INN); Fluothane (TN) |
(P) Enzyme: CYP3A4 |
| D00544 |
Methoxyflurane (USP/INN); Penthrane (TN) |
(P) Enzyme: CYP3A4 |
| D00545 |
Isoflurane (JP18/USP/INN); Forane (TN) |
(P) unclassified |
| D00546 |
Desflurane (JAN/USP/INN); Suprane (TN) |
(P) unclassified |
| D00549 |
Propofol (JAN/USP/INN); Diprivan (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00554 |
Ethinyl estradiol (USP); Ethinylestradiol (JP18/INN); Estinyl (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00555 |
Amobarbital (JP18/INN); Isomytal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00560 |
Pimozide (JP18/USP/INN); Orap (TN) |
(P) Enzyme: CYP3A4 |
| D00563 |
Mirtazapine (JAN/USP/INN); Remeron (TN); Reflex (TN) |
(P) Enzyme: CYP3A4 |
| D00570 |
Colchicine (JP18/USP); Colchicine (TN) |
(P) Enzyme: CYP3A4 |
| D00578 |
Voriconazole (JP18/USP/INN); Vfend (TN) |
(P) unclassified |
| D00585 |
Mifepristone (JAN/USAN/INN); Korlym (TN); Mifeprex (TN) |
(P) Enzyme: CYP3A4 |
| D00592 |
Dapsone (USP); Diaphenylsulfone (JAN); Aczone (TN) |
(P) Enzyme: CYP3A4 |
| D00594 |
Repaglinide (JAN/USP/INN); Prandin (TN); Surepost (TN) |
(P) unclassified |
| D00605 |
Guanabenz acetate (JP18/USP); Wytensin (TN) |
(P) unclassified |
| D00606 |
Guanfacine hydrochloride (JAN/USP); Intuniv (TN); Tenex (TN) |
(P) Enzyme: CYP3A4 |
| D00615 |
Amlodipine besylate (USP); Amlodipine besilate (JP18); Norvasc (TN) |
(P) Enzyme: CYP3A4 |
| D00616 |
Diltiazem hydrochloride (JP18/USP); Cardizem (TN); Cartia XT (TN); Dilacor XR (TN); Dilt-CD (TN) |
(P) Enzyme: CYP3A4 |
| D00617 |
Nicardipine hydrochloride (JP18/USAN); Cardene (TN) |
(P) Enzyme: CYP3A4 |
| D00618 |
Nisoldipine (JAN/USAN/INN); Sular (TN) |
(P) Enzyme: CYP3A4 |
| D00619 |
Verapamil hydrochloride (JP18/USP); Calan (TN); Covera-hs (TN); Vasolan (TN); Verelan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00629 |
Nitrendipine (JP18/USAN/INN); Baypress (TN) |
(P) Enzyme: CYP3A4 |
| D00631 |
Bepridil hydrochloride (USAN); Bepridil hydrochloride hydrate (JAN); Vascor (TN) |
(P) Enzyme: CYP3A4 |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(P) Enzyme: CYP3A4 |
| D00637 |
Disopyramide phosphate (JAN/USP); Norpace (TN) |
(P) Enzyme: CYP3A4 |
| D00640 |
Propafenone hydrochloride (JP18/USP); Rythmol (TN) |
(P) Enzyme: CYP3A4 |
| D00646 |
Tolterodine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D00653 |
Dorzolamide hydrochloride (JP18/USP); Trusopt (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D00661 |
Cevimeline hydrochloride (USAN); Cevimeline hydrochloride hydrate (JAN); Evoxac (TN); Saligren (TN) |
(P) Enzyme: CYP3A4 |
| D00665 |
Chlorpheniramine maleate (JP18/USP); Chlor-trimeton (TN); Teldrin (TN) |
(P) unclassified |
| D00669 |
Diphenhydramine hydrochloride (JP18/USP); Benadryl (TN) |
(P) unclassified |
| D00670 |
Donepezil hydrochloride (JP18/USP); Aricept (TN) |
(P) Enzyme: CYP3A4 |
| D00673 |
Ranitidine hydrochloride (JP18/USP); Zantac (TN) |
(P) unclassified |
| D00674 |
Naratriptan hydrochloride (JAN/USP); Amerge (TN) |
(P) Enzyme: CYP3A4 |
| D00677 |
Granisetron hydrochloride (JAN/USP); Kytril (TN) |
(P) Enzyme: CYP3A4 |
| D00678 |
Ondansetron hydrochloride hydrate (JAN/USP); Ondansetron hydrochloride; Zofran (TN) |
(P) Enzyme: CYP3A4 |
| D00679 |
Ergotamine tartrate (JP18/USP); Ergomar (TN) |
(P) Enzyme: CYP3A4 |
| D00680 |
Methylergonovine maleate (USP); Methylergometrine maleate (JP18); Methergine (TN) |
(P) Enzyme: CYP3A4 |
| D00687 |
Salmeterol xinafoate (JAN/USP); Serevent (TN) |
(P) Enzyme: CYP3A4 |
| D00689 |
Beclomethasone dipropionate (USP); Beclometasone dipropionate (JP18); Beclovent (TN); Qnasl (TN); Vanceril (TN) |
(P) Enzyme: CYP3A4 |
| D00690 |
Mometasone furoate (JAN/USP); Asmanex (TN); Elocon (TN) |
(P) Enzyme: CYP3A4 |
| D00696 |
Midazolam hydrochloride (USAN); Versed (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00697 |
Flumazenil (JAN/USP/INN); Romazicon (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00698 |
Aprobarbital (INN); Alurate (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00699 |
Butabarbital sodium (USP); Secbutabarbital sodium (INN); Butabarb (TN); Butisol sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00700 |
Mephobarbital (JAN/USP); Methylphenobarbital (INN); Mebaral (TN) |
(P) Enzyme: CYP2C19 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00706 |
Zolpidem tartrate (JP18/USP); Ambien (TN); Intermezzo (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00707 |
Fomepizole (JAN/USAN/INN); Antizol (TN) |
(P) CYP inhibition: CYP3A4 |
| D00710 |
Valproate sodium (USAN); Sodium valproate (JP18); Depakene (TN); Selenica (TN) |
(P) unclassified |
| D00712 |
Methohexital sodium (USP); Brevital sodium (TN) |
(P) Target: GABRA1 |
| D00713 |
Thiamylal sodium (JP18); Surital (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00714 |
Thiopental sodium (JP18/USP/INN); Pentothal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00722 |
Oxybutynin chloride (USP); Oxybutynin hydrochloride (JP18); Ditropan (TN); Gelnique (TN) |
(P) Enzyme: CYP3A4 |
| D00724 |
Rabeprazole sodium (JP18/USP); Aciphex (TN); Pariet (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D00729 |
Loperamide hydrochloride (JAN/USP); Imodium (TN) |
(P) Enzyme: CYP3A4 |
| D00749 |
Leflunomide (JAN/USP/INN); Arava (TN) |
(P) Enzyme: CYP3A4 |
| D00751 |
Methylprednisolone sodium succinate (JAN/USP); A-methapred (TN); Solu-medrol (TN) |
(P) Enzyme: CYP3A4 |
| D00753 |
Sirolimus (JAN/USAN/INN); Rapamune (TN); Rapamycin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00754 |
Thalidomide (JAN/USP/INN); Thalomid (TN); Thaled (TN) |
(P) unclassified |
| D00769 |
Clopidogrel bisulfate (USP); Clopidogrel sulfate (JP18); Clopidogrel sulfate tablets (JP18); Clopidogrel hydrogen sulphate; Isocover (TN); Plavix (TN) |
(P) Enzyme: CYP2C19 |
| D00780 |
Bromocriptine mesylate (USP); Bromocriptine mesilate (JP18); Parlodel (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00783 |
Botulinum toxin type A (JAN); Botox (TN); Dysport (TN) |
(P) unclassified |
| D00785 |
Selegiline hydrochloride (JAN/USP); Eldepryl (TN) |
(P) Enzyme: CYP3A4 |
| D00788 |
Acetophenazine maleate (USAN); Tindal (TN) |
(P) unclassified |
| D00789 |
Chlorpromazine hydrochloride (JP18/USP); Sonazine (TN) |
(P) unclassified |
| D00791 |
Fluphenazine hydrochloride (JAN/USP); Prolixin (TN) |
(P) unclassified |
| D00792 |
Fluphenazine enanthate (JP18/USP); Prolixin enanthate (TN) |
(P) unclassified |
| D00793 |
Fluphenazine decanoate (JAN/USP); Prolixin decanoate (TN) |
(P) unclassified |
| D00794 |
Loxapine succinate (USP); Loxitane (TN) |
(P) Enzyme: CYP3A4 |
| D00795 |
Mesoridazine besylate (USP); Serentil (TN) |
(P) unclassified |
| D00797 |
Promazine hydrochloride (USP); Sparine (TN) |
(P) unclassified |
| D00798 |
Thioridazine hydrochloride (JP18/USP); Mellaril (TN) |
(P) unclassified |
| D00799 |
Trifluoperazine hydrochloride (JAN/USP); Stelazine (TN) |
(P) unclassified |
| D00800 |
Triflupromazine hydrochloride (JAN/USP); Vesprin (TN) |
(P) unclassified |
| D00804 |
Ivermectin (JAN/USP/INN); Sklice (TN); Soolantra (TN); Stromectol (TN) |
(P) Enzyme: CYP3A4 |
| D00809 |
Amitriptyline hydrochloride (JP18/USP); Elavil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D00811 |
Clomipramine hydrochloride (JP18/USP); Anafranil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D00815 |
Imipramine hydrochloride (JP18/USP); Tofranil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D00818 |
Maprotiline hydrochloride (JP18/USP); Ludiomil (TN) |
(P) unclassified |
| D00820 |
Trazodone hydrochloride (JAN/USP); Desyrel (TN) |
(P) Enzyme: CYP3A4 |
| D00821 |
Venlafaxine hydrochloride (JAN/USP); Effexor (TN) |
(P) unclassified |
| D00822 |
Citalopram hydrobromide (USP); Celexa (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2C19 |
| D00823 |
Fluoxetine hydrochloride (JAN/USP); Prozac (TN); Sarafem (TN) |
(P) CYP inhibition: CYP2C19 |
| D00824 |
Fluvoxamine maleate (JP18/USP); Luvox (TN) |
(P) CYP inhibition: CYP2C19 CYP3A4 |
| D00825 |
Sertraline hydrochloride (JAN/USP); Zoloft (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D00826 |
Tranylcypromine sulfate (USP); Parnate (TN) |
(P) unclassified |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00835 |
Alfentanil hydrochloride (USP); Alfenta (TN) |
(P) unclassified |
| D00836 |
Buprenorphine hydrochloride (JP18/USP); Buprenex (TN) |
(P) Enzyme: CYP3A4 |
| D00837 |
Butorphanol tartrate (JAN/USP); Stadol (TN) |
(P) unclassified |
| D00838 |
Dezocine (USAN); Dalgan (TN) |
(P) unclassified |
| D00839 |
Hydromorphone hydrochloride (JAN/USP); Dilaudid (TN); Exalgo (TN); Palladone (TN) |
(P) unclassified |
| D00840 |
Levomethadyl acetate hydrochloride (USAN); Orlaam (TN) |
(P) Enzyme: CYP3A4 |
| D00841 |
Levorphanol tartrate (USP); Levorphanol tartrate dihydrate; Levo-dromoran (TN) |
(P) unclassified |
| D00842 |
Morphine sulfate (USP); Morphine sulfate hydrate (JP18); Morphine sulfate pentahydrate; Astramor PH (TN); Avinza (TN); Depodur (TN); Kadian (TN); MS contin (TN) |
(P) unclassified |
| D00843 |
Nalbuphine hydrochloride (USAN); Nubain (TN) |
(P) unclassified |
| D00844 |
Oxymorphone hydrochloride (USP); Numorphan (TN); Opana (TN) |
(P) unclassified |
| D00845 |
Sufentanil citrate (USP); Dsuvia (TN); Sufenta (TN) |
(P) unclassified |
| D00847 |
Oxycodone hydrochloride (USP); Oxecta (TN); Oxycontin (TN); Roxicodone (TN) |
(P) Enzyme: CYP3A4 |
| D00851 |
Erythromycin estolate (USP); Erythromycin estorate (JAN); Ilosone (TN) |
(P) unclassified |
| D00854 |
Quinupristin and dalfopristin; Synercid (TN) |
(P) CYP inhibition: CYP3A4 |
| D00882 |
Miconazole nitrate (JP18/USP); Micatin (TN); Monistat (TN) |
(P) unclassified |
| D00887 |
Atorvastatin calcium anhydorous; Lipitor (TN) |
(P) Enzyme: CYP3A4 |
| D00889 |
Cerivastatin sodium (JAN/USAN); Baycol (TN) |
(P) Enzyme: CYP3A4 |
| D00892 |
Fluvastatin sodium (JAN/USP); Lescol (TN) |
(P) Enzyme: CYP3A4 |
| D00894 |
Amprenavir (JAN/USAN/INN); Agenerase (TN) |
(CI,P) Enzyme: CYP3A4 |
| D00895 |
Delavirdine mesylate (USAN); Delavirdine mesilate (JAN); Rescriptor (TN) |
(P) unclassified |
| D00896 |
Efavirenz (JAN/USP/INN); Sustiva (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00897 |
Indinavir sulfate (USP); Crixivan (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00899 |
Nelfinavir mesylate (USAN/INN); Nelfinavir mesilate (JAN); Viracept (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00948 |
Estropipate (USP); Piperazine estrone sulfate; Ogen (TN) |
(P) Enzyme: CYP3A4 |
| D00960 |
Anastrozole (JP18/USP/INN); Arimidex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00963 |
Exemestane (JAN/USP/INN); Aromasin (TN) |
(P) Enzyme: CYP3A4 |
| D00964 |
Letrozole (JAN/USP/INN); Femara (TN) |
(P) Enzyme: CYP3A4 |
| D00966 |
Tamoxifen citrate (JP18/USP); Nolvadex (TN); Soltamox (TN) |
(P) Enzyme: CYP3A4 |
| D00967 |
Toremifene citrate (JAN/USAN); Fareston (TN) |
(P) Enzyme: CYP3A4 |
| D00969 |
Meloxicam (JAN/USP/INN); Mobic (TN) |
(P) unclassified |
| D00975 |
Dexamethasone sodium phosphate (JAN/USP); Dalalone (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00979 |
Methylprednisolone acetate (JAN/USP); Depo-medrol (TN) |
(P) Enzyme: CYP3A4 |
| D00987 |
Cabergoline (JP18/USP/INN); Cabaser (TN); Dostinex (TN) |
(P) Enzyme: CYP3A4 |
| D01007 |
Propiverine hydrochloride (JP18); Bup-4 (TN); Mictonorm (TN) |
(P) Enzyme: CYP3A4 |
| D01061 |
Irinotecan hydrochloride (USP); Irinotecan hydrochloride hydrate (JP18); Irinotecan hydrochloride trihydrate; CPT 11; CPT-11; Campto (TN); Camptosar (TN); Onivyde (TN) |
(P) unclassified |
| D01068 |
Vinblastine sulfate (JP18/USP); Exal (TN); Velban (TN) |
(P) Enzyme: CYP3A4 |
| D01071 |
Hexobarbital (JAN/INN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01078 |
Telithromycin (JAN/USAN/INN); Ketek (TN) |
(P) unclassified |
| D01097 |
Lazabemide hydrochloride (JAN/USAN); Tempium (TN) |
(P) unclassified |
| D01098 |
Maxacalcitol (JAN/USAN/INN); Oxarol (TN); Prezios (TN) |
(P) Enzyme: CYP3A4 |
| D01101 |
Bromperidol (JAN/USAN/INN); Impromen (TN) |
(P) Enzyme: CYP3A4 |
| D01104 |
Barnidipine hydrochloride (JAN); Hypoca (TN) |
(P) Enzyme: CYP3A4 |
| D01115 |
Eplerenone (JP18/USAN/INN); Inspra (TN) |
(P) Enzyme: CYP3A4 |
| D01121 |
Rebamipide (JP18/INN); Mucosta (TN) |
(P) Enzyme: CYP3A4 |
| D01130 |
Thiethylperazine maleate (JAN/USP); Norzine (TN) |
(P) unclassified |
| D01131 |
Lafutidine (JP18/INN); Protecadin (TN) |
(P) Enzyme: CYP3A4 |
| D01145 |
Azelnidipine (JP18/INN); Calblock (TN) |
(P) Enzyme: CYP3A4 |
| D01148 |
Tolterodine tartrate (JAN/USP); Detrol (TN); Detrusitol (TN) |
(P) Enzyme: CYP3A4 |
| D01160 |
Saquinavir mesylate (USP); Saquinavir mesilate (JAN); Invirase (TN) |
(CI,P) Enzyme: CYP3A4 |
| D01161 |
Fulvestrant (JAN/USP/INN); Faslodex (TN) |
(P) Enzyme: CYP3A4 |
| D01163 |
Ergonovine maleate (USP); Ergometrine maleate (JP18); Ergometrine (TN) |
(P) Enzyme: CYP3A4 |
| D01164 |
Aripiprazole (JAN/USP/INN); Abilify (TN) |
(P) Enzyme: CYP3A4 |
| D01173 |
Cilnidipine (JP18/INN); Atelec (TN) |
(P) Enzyme: CYP3A4 |
| D01176 |
Blonanserin (JAN/INN); AD 5423 |
(P) Enzyme: CYP3A4 |
| D01177 |
Remifentanil hydrochloride (JAN/USAN); Ultiva (TN) |
(P) unclassified |
| D01205 |
Dexmedetomidine hydrochloride (JAN/USP); Igalmi (TN); Precedex (TN) |
(P) Enzyme: CYP2C19 |
| D01207 |
Omeprazole sodium (USAN); Losec sodium (TN) |
(P) Enzyme: CYP2C19 |
| D01213 |
Tolvaptan (JAN/USAN/INN); Samsca (TN) |
(P) Enzyme: CYP3A4 |
| D01217 |
Dydrogesterone (JP18/USP/INN); Duphaston (TN); Gynorest (TN) |
(P) Enzyme: CYP3A4 |
| D01227 |
Bosentan (USAN); Bosentan hydrate (JAN); Tracleer (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01235 |
Josamycin (JP18/USAN/INN); Leucomycin A3; JM; Josamycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01236 |
Conivaptan hydrochloride (JAN/USAN); Vaprisol (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01269 |
Solifenacin succinate (JAN/USAN/INN); Vesicare (TN) |
(P) Enzyme: CYP3A4 |
| D01276 |
Atazanavir sulfate (JAN/USAN); Reyataz (TN) |
(CI,P) CYP inhibition: CYP3A4 |
| D01287 |
Levobupivacaine hydrochloride (JAN/USAN); Chirocaine (TN) |
(P) Enzyme: CYP3A4 |
| D01293 |
Ethyl loflazepate (JP18/INN); Meilax (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01310 |
Secobarbital sodium (JAN/USP); Seconal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01316 |
Mexazolam (JAN/INN); Melex (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01322 |
Troleandomycin (USAN/INN); Triacetyloleandomycin (JAN); TAO; Tao (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D01339 |
Midecamycin (JP18/INN); Medemycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01355 |
Tramadol hydrochloride (JP18/USP); Ultram (TN) |
(P) Enzyme: CYP3A4 |
| D01358 |
Mianserin hydrochloride (JAN/USAN); Tetramide (TN) |
(P) Enzyme: CYP3A4 |
| D01361 |
Erythromycin ethylsuccinate (JP18/USP); E.E.S. (TN); Eryped (TN); Erythrocin W (TN) |
(P) unclassified |
| D01372 |
Zopiclone (JP18/INN); Amoban (TN); Zopiclone (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01382 |
Metharbital (JAN/INN); Gemonil (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01383 |
Meperidine hydrochloride (USP); Pethidine hydrochloride (JP18); Demerol (TN) |
(P) unclassified |
| D01389 |
Chlophedianol hydrochloride (USAN); Clofedanol hydrochloride (JP18); Coldrin (TN) |
(P) unclassified |
| D01399 |
Fentanyl citrate (JP18/USP); Abstral (TN); Fentora (TN); Lazanda (TN); Oralet (TN) |
(P) Enzyme: CYP3A4 |
| D01412 |
Perazine maleate (JAN) |
(P) unclassified |
| D01413 |
Estradiol valerate (JAN/USP/INN); Deladumone (TN) |
(P) Enzyme: CYP3A4 |
| D01418 |
Tamibarotene (JAN/USAN/INN); Am 80; Amnoid (TN) |
(P) Enzyme: CYP3A4 |
| D01425 |
Lopinavir (JAN/USP/INN) |
(CI,P) unclassified |
| D01429 |
Fosfluconazole (JAN/INN); Prodif (TN) |
(P) CYP inhibition: CYP2C19 CYP3A4 |
| D01441 |
Imatinib mesylate (USAN); Imatinib mesilate (JAN); Gleevec (TN); Glivec (TN) |
(P) Enzyme: CYP3A4 |
| D01447 |
Thioproperazine mesilate (JAN); Thioproperazine mesylate |
(P) unclassified |
| D01448 |
Trifluoperazine maleate (JAN); Trifluoperazine (TN) |
(P) unclassified |
| D01450 |
Bupivacaine hydrochloride (USP); Bupivacaine hydrochloride hydrate (JP18); Marcaine (TN) |
(P) Enzyme: CYP3A4 |
| D01453 |
Caffeine hydrate (JP18); Caffeine monohydrate; Caffeine (TN) |
(P) unclassified |
| D01455 |
Cifenline succinate (USAN); Cibenzoline succinate (JP18); Cibenol (TN); Cipralan (TN) |
(P) Enzyme: CYP3A4 |
| D01468 |
Nemonapride (JAN/INN); Emilace (TN) |
(P) Enzyme: CYP3A4 |
| D01478 |
Ebastine (JP18/USAN/INN); Kestine (TN) |
(P) Enzyme: CYP3A4 |
| D01481 |
Dihydrocodeine phosphate (JP18); Dihydro (TN) |
(P) unclassified |
| D01485 |
Propericiazine (JAN); Periciazine; Neuleptil (TN) |
(P) unclassified |
| D01501 |
Isoniazid calcium pyruvinate (JAN); Pyruvic acid calcium isoniazid |
(P) unclassified |
| D01510 |
Dexamethasone metasulfobenzoate sodium (JAN); Dexamethazone metasulfobenzoate sodium; Dexapos; Santeson (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01514 |
Etizolam (JP18/INN); Sedekopan (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01520 |
Levomepromazine hydrochloride (JAN/USAN); Nozinan (TN) |
(P) unclassified |
| D01553 |
Manidipine hydrochloride (JP18); Manidipine dihydrochloride; Calslot (TN) |
(P) Enzyme: CYP3A4 |
| D01562 |
Aranidipine (JAN/INN); Sapresta (TN) |
(P) Enzyme: CYP3A4 |
| D01564 |
Rilmazafone hydrochloride hydrate (JP18); Rilmazafone hydrochloride dihydrate; Rilmazafone hydrochloride; Rhythmy (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01615 |
Dexamethasone palmitate (JAN); Dexamethasone 21-palmitate; Limethason (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01617 |
Estradiol dipropionate (JAN); Ovahormon (TN) |
(P) Enzyme: CYP3A4 |
| D01624 |
Sarpogrelate hydrochloride (JP18); Anplag (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D01632 |
Dexamethasone dipropionate (USAN); Dexamethasone propionate (JAN); Hifmeta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01636 |
Midecamycin acetate (JP18); Miocamycin; Miocamycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01663 |
Quinine ethylcarbonate (JP18); Quinine ethylcarbonate (TN) |
(P) Enzyme: CYP3A4 |
| D01692 |
Alfuzosin hydrochloride (JAN/USAN); Uroxatral (TN) |
(P) Enzyme: CYP3A4 |
| D01699 |
Darifenacin hydrobromide (JAN/USAN); Enablex (TN) |
(P) Enzyme: CYP3A4 |
| D01703 |
Ciclesonide (JAN/USAN/INN); Alvesco (TN); Omnaris (TN); Zetonna (TN) |
(P) Enzyme: CYP3A4 |
| D01708 |
Fluticasone propionate (JAN/USP); Cutivate (TN); Flonase (TN); Flovent (TN) |
(P) Enzyme: CYP3A4 |
| D01740 |
Barbital (JP18/INN); Barbital (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01744 |
Brotizolam (JP18/USAN/INN); Lendormin (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01745 |
Domperidone (JP18/USAN/INN); Motilium (TN) |
(P) Enzyme: CYP3A4 |
| D01832 |
Modafinil (JAN/USP/INN); Provigil (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2C19 / CYP induction: CYP3A4 |
| D01855 |
Mozavaptane hydrochloride (JAN) |
(P) Enzyme: CYP3A4 |
| D01860 |
Perazine dimalonate (JAN) |
(P) unclassified |
| D01872 |
Doxapram hydrochloride (USP); Doxapram hydrochloride hydrate (JP18); Dopram (TN) |
(P) Enzyme: CYP3A4 |
| D01879 |
Eptazocine hydrobromide (JAN); Sedapain (TN) |
(P) unclassified |
| D01888 |
Safrazine hydrochloride (JAN) |
(P) unclassified |
| D01896 |
Cilostazol (JP18/USP/INN); Pletal (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D01898 |
Haloperidol decanoate (JAN/USP); Halomonth (TN) |
(P) Enzyme: CYP3A4 |
| D01908 |
Nilvadipine (JP18/USAN/INN); Nivadil (TN) |
(P) Enzyme: CYP3A4 |
| D01935 |
Vinorelbine tartrate (USP); Vinorelbine ditartrate (JAN); KW 2307; Navelbine (TN) |
(P) Enzyme: CYP3A4 |
| D01948 |
Dexamethasone valerate (JAN); Dexamethasone 17-valerate; DV-17; Voalla ointment (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01953 |
Estradiol benzoate (JP18/USP); Ovahormon (TN) |
(P) Enzyme: CYP3A4 |
| D01965 |
Silodosin (JP18/INN); KMD 3213; Rapaflo (TN); Urief (TN) |
(P) Enzyme: CYP3A4 |
| D01973 |
Eletriptan hydrobromide (JAN/USAN); Relpax (TN) |
(P) Enzyme: CYP3A4 |
| D01980 |
Luliconazole (JAN/USAN/INN); Lulicon (TN); Luzu (TN) |
(P) CYP inhibition: CYP2C19 CYP3A4 |
| D01984 |
Esomeprazole magnesium (USP); Esomeprazole magnesium hydrate (JAN); Esomeprazole magnesium trihydrate; Nexium (TN) |
(P) Enzyme: CYP2C19 |
| D01994 |
Mosapride citrate hydrate (JP18); Mosapride citrate dihydrate; Gasmotin (TN) |
(P) Enzyme: CYP3A4 |
| D02002 |
Isoniazid sodium methanesulfonate hydrate (JAN); Isoniazid sodium methanesulfonate monohydrate; Isoniazid sodium methanesulfonate; IHMS; Neoiscotin (TN) |
(P) unclassified |
| D02008 |
Tadalafil (JAN/USP/INN); Adcirca (TN); Cialis (TN); Zalutia (TN) |
(P) Enzyme: CYP3A4 |
| D02009 |
Erythromycin lactobionate (JP18/USP); Erythrocin (TN) |
(P) unclassified |
| D02022 |
Prochlorperazine mesilate (JAN); Prochlorperazine dimethanesulfonate; Novamin (TN) |
(P) unclassified |
| D02037 |
Perphenazine maleate (JP18); PZC (TN) |
(P) unclassified |
| D02045 |
Benidipine hydrochloride (JP18); KW 3049; Coniel (TN) |
(P) Enzyme: CYP3A4 |
| D02086 |
Lidocaine hydrochloride (JAN/USP); Dalcaine (TN); Xylocaine (TN) |
(P) Enzyme: CYP3A4 |
| D02101 |
Codeine phosphate (USP); Codeine phosphate hydrate (JP18); Codeine (TN) |
(P) unclassified |
| D02102 |
Methadone hydrochloride (JAN/USP); Dolophine hydrochloride (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP induction: CYP3A4 |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) unclassified |
| D02111 |
Pentazocine lactate (USP); Talwin (TN) |
(P) unclassified |
| D02114 |
Hydroxychloroquine sulfate (JAN/USP); Plaquenil (TN) |
(P) Enzyme: CYP3A4 |
| D02163 |
Fluphenazine maleate (JAN); Flumezin (TN) |
(P) unclassified |
| D02165 |
Docetaxel (USP); Docetaxel hydrate (JP18); Docetaxel trihydrate; Taxotere (TN) |
(P) Enzyme: CYP3A4 |
| D02173 |
Galantamine hydrobromide (JAN/USP); Razadyne (TN); Reminyl (TN) |
(P) Enzyme: CYP3A4 |
| D02174 |
Dexamethasone acetate (JAN/USP); Decadronal (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02175 |
Compound oxycodone (JP18); Pavinal (TN) |
(P) Enzyme: CYP3A4 |
| D02184 |
Erythromycin stearate (JP18/USP); Bristamycin (TN) |
(P) unclassified |
| D02205 |
Ethylmorphine hydrochloride hydrate (JP18); Ethylmorphine hydrochloride dihydrate; Ethylmorphine hydrochloride (TN) |
(P) Enzyme: CYP3A4 |
| D02211 |
Dihydroergotamine mesylate (USP); Dihydroergotamine mesilate (JP18); Migranal (TN); Trudhesa (TN) |
(P) Enzyme: CYP3A4 |
| D02216 |
Ciprofloxacin hydrochloride (USP); Ciprofloxacin hydrochloride hydrate (JP18); Ciloxan (TN); Cipro (TN); Proquin XR (TN) |
(P) unclassified |
| D02219 |
Terbinafine hydrochloride (JP18/USP); Lamisil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D02227 |
Pentazocine hydrochloride (JAN/USP); Sosegon (TN); Talacen (TN) |
(P) unclassified |
| D02229 |
Sildenafil citrate (JAN/USP); Revatio (TN); Viagra (TN) |
(P) Enzyme: CYP3A4 |
| D02234 |
Cyproheptadine hydrochloride (JP18/USP); Cyproheptadine hydrochloride sesquihydrate; Periactin (TN) |
(P) unclassified |
| D02245 |
Trimeprazine tartrate (USP); Alimemazine tartrate (JP18); Alimezine (TN) |
(P) unclassified |
| D02248 |
Levomepromazine maleate (JP18/USAN); Hirnamin (TN) |
(P) unclassified |
| D02252 |
Amobarbital sodium (JAN/USP); Amytal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02253 |
Pentobarbital calcium (JP18); Ravona (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02258 |
Atorvastatin calcium (USP); Atorvastatin calcium hydrate (JP18); Atorvastatin calcium trihydrate; Atorvaliq (TN); Lipitor (TN) |
(P) Enzyme: CYP3A4 |
| D02261 |
Quinine hydrochloride hydrate (JP18); Quinine hydrochloride dihydrate; Quinine hydrochloride (TN) |
(P) Enzyme: CYP3A4 |
| D02262 |
Quinine sulfate (USP); Quinine sulfate hydrate (JP18); Quinine hydrogen sulfate; Coco-quinine (TN) |
(P) Enzyme: CYP3A4 |
| D02268 |
Ergoloid mesylates (USP); Dihydroergotoxine mesilate (JP18); Circanol (TN); Hydergine (TN); Inorter (TN) |
(P) Enzyme: CYP3A4 |
| D02271 |
Morphine hydrochloride hydrate (JP18); Morphine hydrochloride trihydrate; Anpec (TN) |
(P) unclassified |
| D02274 |
Dantrolene sodium (USP); Dantrolene sodium hydrate (JP18); Dantrium (TN); Ryanodex (TN) |
(P) unclassified |
| D02283 |
Iomazenil (123I) (JAN/INN); Benzodine (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02340 |
Loxapine (USAN/INN); Adasuve (TN) |
(P) Enzyme: CYP3A4 |
| D02354 |
Thiethylperazine (USAN/INN) |
(P) unclassified |
| D02356 |
Verapamil (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02360 |
Sertraline (INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) unclassified |
| D02375 |
Terbinafine (USAN/INN); Lamasil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D02404 |
Procaterol hydrochloride (USAN); Pro-Air (TN) |
(P) Enzyme: CYP3A4 |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02497 |
Fosamprenavir (INN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02498 |
Lopinavir and ritonavir; Kaletra (TN) |
(CI,P) unclassified |
| D02523 |
Erythromycin acistrate (USAN); Erasis (TN) |
(P) unclassified |
| D02524 |
Erythromycin gluceptate (USP); Erythromycin glucoheptonate; Ilotycin gluceptate (TN) |
(P) unclassified |
| D02525 |
Erythromycin propionate (USAN) |
(P) unclassified |
| D02537 |
Dronedarone (INN) |
(P) unclassified |
| D02554 |
Rifaximin (JAN/USAN/INN); Xifaxan (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02555 |
Posaconazole (JAN/USAN/INN); Noxafil (TN) |
(P) CYP inhibition: CYP3A4 |
| D02556 |
Ravuconazole (prop.INN) |
(P) unclassified |
| D02559 |
Toloxatone (INN); Humoryl (TN) |
(P) unclassified |
| D02560 |
Brofaromine (INN); Consonar (TN) |
(P) unclassified |
| D02561 |
Moclobemide (USAN/INN); Aurorix (TN) |
(P) Enzyme: CYP2C19 / CYP inhibition: CYP2C19 |
| D02562 |
Rasagiline mesylate (USAN); Rasagiline mesilate (JAN); Azilect (TN) |
(P) unclassified |
| D02563 |
Befloxatone (INN) |
(P) unclassified |
| D02564 |
Pargyline hydrochloride (USAN); Eutonyl (TN) |
(P) unclassified |
| D02567 |
Escitalopram oxalate (JAN/USP); Lexapro (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D02570 |
Desvenlafaxine succinate (USAN); Desvenlafaxine succinate hydrate (JAN); Desvenlafaxine succinate monohydrate; Pristiq (TN) |
(P) Enzyme: CYP3A4 |
| D02577 |
Flibanserin (USAN/INN); Addyi (TN) |
(P) Enzyme: CYP3A4 |
| D02579 |
Iproniazid (INN) |
(P) unclassified |
| D02580 |
Isocarboxazid (INN); Marplan (TN) |
(P) unclassified |
| D02581 |
Cimoxatone (INN) |
(P) unclassified |
| D02591 |
Dexamethasone acefurate (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02592 |
Dexamethasone beloxil (USAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02593 |
Pantoprazole sodium (USP); Pantoprazole sodium hydrate (JAN); Protonix (TN) |
(P) Enzyme: CYP2C19 |
| D02604 |
Acepromazine maleate (USP) |
(P) unclassified |
| D02605 |
Methoxypromazine maleate |
(P) unclassified |
| D02607 |
Mepazine acetate |
(P) unclassified |
| D02608 |
Perazine fendizoate (JAN) |
(P) unclassified |
| D02609 |
Prochlorperazine edisylate (USP); Compazine syrup (TN) |
(P) unclassified |
| D02610 |
Thiethylperazine malate (JAN); Torecan (TN) |
(P) unclassified |
| D02611 |
Phenoperidine (INN) |
(P) unclassified |
| D02618 |
Butobarbital (BAN); Butethal; Neonal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02624 |
Eszopiclone (JAN/USP/INN); Estorra (TN); Lunesta (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02626 |
Bromperidol decanoate (USAN) |
(P) Enzyme: CYP3A4 |
| D02642 |
Butaperazine (USAN) |
(P) unclassified |
| D02643 |
Butaperazine maleate (USAN) |
(P) unclassified |
| D02644 |
Carphenazine maleate (USAN); Proketazine (TN) |
(P) unclassified |
| D02653 |
Cyclophenazine hydrochloride (USAN) |
(P) unclassified |
| D02666 |
Iloperidone (USAN/INN); Fanapt (TN) |
(P) Enzyme: CYP3A4 |
| D02671 |
Mesoridazine (USAN/INN); Lidanar (TN) |
(P) unclassified |
| D02679 |
Piperacetazine (USAN/INN); Quide (TN) |
(P) unclassified |
| D02680 |
Pipotiazine palmitate (USAN); Piportil depot (TN) |
(P) unclassified |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) CYP inhibition: CYP2C19 |
| D02714 |
Everolimus (JAN/USAN/INN); Afinitor (TN); Votubia (TN); Zortress (TN) |
(P) Enzyme: CYP3A4 |
| D02731 |
Vardenafil dihydrochoride (USAN); Levitra (TN) |
(P) Enzyme: CYP3A4 |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 |
| D02735 |
Rimabotulinumtoxin B (USAN); Botulinum toxin type B (JAN); Myobloc (TN) |
(P) unclassified |
| D02740 |
Lidocaine and prilocaine; Lidocaine and propitocaine; Emla (TN); Oraqix (TN); Lidocaine and prilocaine (TN) |
(P) Enzyme: CYP3A4 |
| D02817 |
Allobarbital (USAN/INN) |
(P) unclassified |
| D02824 |
Almotriptan (USAN) |
(P) Enzyme: CYP3A4 |
| D02825 |
Almotriptan malate (USP); Axert (TN) |
(P) Enzyme: CYP3A4 |
| D02829 |
Alosetron hydrochloride (USAN); Lotrpnex (TN) |
(P) unclassified |
| D02861 |
Indinavir sulfate ethanolate (JAN); Crixivan (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02867 |
Fosamprenavir calcium hydrate (JAN); Lexiva (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02910 |
Amiodarone (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D02914 |
Amlodipine maleate (USAN); Amvaz (TN) |
(P) Enzyme: CYP3A4 |
| D02941 |
Anileridine (USP/INN) |
(P) unclassified |
| D02942 |
Anileridine hydrochloride (USP); Leritine (TN) |
(P) unclassified |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D03098 |
Berythromycin (USAN/INN); Erythromycin B |
(P) unclassified |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03156 |
Brifentanil hydrochloride (USAN) |
(P) unclassified |
| D03165 |
Bromocriptine (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03180 |
Butabarbital (USP); Secbutabarbital (BAN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D03182 |
Butalbital (USP/INN); Sandoptal (TN) |
(P) unclassified |
| D03197 |
Butorphanol (USAN/INN) |
(P) unclassified |
| D03208 |
Aliskiren (USAN/INN); Rasilez (TN) |
(P) Enzyme: CYP3A4 |
| D03213 |
Apixaban (JAN/USAN/INN); Eliquis (TN) |
(P) Enzyme: CYP3A4 |
| D03215 |
Armodafinil (USAN/INN); Nuvigil (TN) |
(P) Enzyme: CYP3A4 |
| D03217 |
Avanafil (USAN/INN); Stendra (TN); Spedra (TN) |
(P) Enzyme: CYP3A4 |
| D03218 |
Axitinib (JAN/USAN); Inlyta (TN) |
(P) Enzyme: CYP3A4 |
| D03239 |
Ladostigil tartrate (USAN) |
(P) unclassified |
| D03248 |
Clorgiline (INN); Clorgyline |
(P) unclassified |
| D03252 |
Bosutinib (USAN) |
(P) Enzyme: CYP3A4 |
| D03253 |
Brecanavir (USAN) |
(CI) unclassified |
| D03259 |
Gemtuzumab ozogamicin (USAN); Gemtuzumab ozogamicin (genetical recombination) (JAN); Gemtuzumab (INN); Mylotarg (TN) |
(P) Enzyme: CYP3A4 |
| D03260 |
Vardenafil hydrochloride hydrate (JAN); Vardenafil monohydrochloride trihydrate; Levitra (TN); Staxyn (TN) |
(P) Enzyme: CYP3A4 |
| D03274 |
Chlorpromazine hibenzate (JAN); Contomin (TN) |
(P) unclassified |
| D03325 |
Mometasone furoate hydrate (JAN); Mometasone furoate monohydrate; Nasonex (TN) |
(P) Enzyme: CYP3A4 |
| D03405 |
Carfentanil citrate (USAN) |
(P) unclassified |
| D03409 |
Caroxazone (USAN/INN) |
(P) unclassified |
| D03415 |
Carvedilol phosphate (USAN); Carvedilol phosphate hydrate (JAN); Coreg CR (TN) |
(P) Enzyme: CYP3A4 |
| D03444 |
Opium (USP); Opium, powdered (JP18); Diluted opium powder (JP18) |
(P) unclassified |
| D03445 |
Opium alkaloids hydrochlorides (JP18); Pan opin (TN) |
(P) unclassified |
| D03492 |
Cifenline (USAN); Cibenzoline (INN) |
(P) Enzyme: CYP3A4 |
| D03503 |
Cimetidine hydrochloride (USP); Cimetidine hydrochloride (TN) |
(P) CYP inhibition: CYP3A4 |
| D03504 |
Cinacalcet (USAN) |
(P) Enzyme: CYP3A4 |
| D03505 |
Cinacalcet hydrochloride (JAN/USAN); Sensipar (TN); Mimpara (TN) |
(P) Enzyme: CYP3A4 |
| D03579 |
Codeine polistirex (USAN) |
(P) unclassified |
| D03580 |
Codeine sulfate (USP); Codeine sulfate trihydrate; Codeine sulfate (TN) |
(P) unclassified |
| D03618 |
Cyclazocine (USAN/INN) |
(P) unclassified |
| D03654 |
Darifenacin (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D03656 |
Darunavir (USAN/INN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP induction: CYP3A4 |
| D03671 |
Deflazacort (USAN/INN); Emflaza (TN) |
(P) Enzyme: CYP3A4 |
| D03725 |
Hydrocodone bitartrate (USP); Hydrocodone bitartrate hemipentahydrate; Dicodid (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D03731 |
Selegiline (USAN/INN); Emsam (TN) |
(P) Enzyme: CYP3A4 |
| D03733 |
Mofegiline hydrochloride (USAN) |
(P) unclassified |
| D03783 |
Oxycodone terephthalate (USP) |
(P) Enzyme: CYP3A4 |
| D03799 |
Dienogest (JAN/USAN/INN); Endometrion (TN) |
(P) Enzyme: CYP3A4 |
| D03820 |
Dutasteride (JAN/USP/INN); Avodart (TN) |
(P) Enzyme: CYP3A4 |
| D03825 |
Dihydrocodeine bitartrate (USP) |
(P) unclassified |
| D03830 |
Diltiazem malate (USAN); Tiamate (TN) |
(P) Enzyme: CYP3A4 |
| D03833 |
Indinavir (USAN); Indinavir hydrate |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03835 |
Fosamprenavir calcium (USAN); Lexiva (TN); Telzir (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03837 |
Fosamprenavir sodium (USAN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03839 |
Droxinavir hydrochloride (USAN) |
(CI) unclassified |
| D03840 |
Palinavir (USAN/INN) |
(CI) unclassified |
| D03842 |
Telinavir (USAN/INN) |
(CI) unclassified |
| D03843 |
Tipranavir disodium (USAN) |
(CI) unclassified |
| D03852 |
Droperidol and fentanyl citrate; Innovar (TN) |
(P) Enzyme: CYP3A4 |
| D03855 |
Pethidine hydrochloride and levallorphan tartrate; Pethilorfan (TN) |
(P) unclassified |
| D03863 |
Opium alkaloids and atropine (JP18); Opium alkaloids hydrochloride and atropine sulfate hydrate; Opiato (TN) |
(P) unclassified |
| D03866 |
Opium alkaloids and scopolamine (JP18); Weak opium alkaloids and scopolamine (JP18); Opium alkaloids hydrochloride and scopolamine hydrobromide hydrate; Opisco (TN) |
(P) unclassified |
| D03914 |
Dronedarone hydrochloride (USP); Multaq (TN) |
(P) unclassified |
| D03917 |
Drospirenone (JAN/USP/INN); Slynd (TN) |
(P) Enzyme: CYP3A4 |
| D04023 |
Erlotinib hydrochloride (JAN/USAN); Tarceva (TN) |
(P) Enzyme: CYP3A4 |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 |
| D04034 |
Chlorpromazine phenolphthalinate (JAN); Wintermin (TN) |
(P) unclassified |
| D04038 |
Perphenazine fendizoate (JAN); PZC (TN) |
(P) unclassified |
| D04048 |
Ropivacaine hydrochloride (USP); Ropivacaine hydrochloride hydrate (JAN); Anapeine (TN) |
(P) Enzyme: CYP3A4 |
| D04052 |
Epinephrine and lidocaine hydrochloride; Adrenaline and lidocaine hydrochloride; Xylocaine (TN) |
(P) Enzyme: CYP3A4 |
| D04054 |
Erythromycin salnacedin (USAN); Erythromycin salnacedin dihydrate |
(P) unclassified |
| D04056 |
Esomeprazole sodium (USAN); Nexium IV (TN) |
(P) Enzyme: CYP2C19 |
| D04061 |
Estradiol acetate (USAN); Femring (TN) |
(P) Enzyme: CYP3A4 |
| D04063 |
Estradiol cypionate (USP); Depo-estradiol (TN) |
(P) Enzyme: CYP3A4 |
| D04064 |
Estradiol enanthate (USAN) |
(P) Enzyme: CYP3A4 |
| D04065 |
Estradiol undecylate (USAN/INN); Delestrec (TN) |
(P) Enzyme: CYP3A4 |
| D04070 |
Estrogens, conjugated (JAN/USP); Conjugated estrogens; Premarin (TN) |
(P) Enzyme: CYP3A4 |
| D04077 |
Eterobarb (USAN/INN); Antilon (TN) |
(P) unclassified |
| D04092 |
Etryptamine acetate (USAN) |
(P) unclassified |
| D04112 |
Etravirine (JAN/USAN/INN); Intelence (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP2C19 / CYP induction: CYP3A4 |
| D04148 |
Fenfluramine hydrochloride (JAN/USAN); Fintepla (TN); Pondimin (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D04214 |
Flunisolide acetate (USAN) |
(P) Enzyme: CYP3A4 |
| D04292 |
Galantamine (USAN/INN); Reminyl (TN) |
(P) Enzyme: CYP3A4 |
| D04300 |
Ganaxolone (USAN/INN); Ztalmy (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D04313 |
Dihydrocodeine phosphate, dl-methylephedrine hydrochloride and Chlorpheniramine maleate; Huscode (TN) |
(P) unclassified |
| D04314 |
Gepirone hydrochloride (USAN); Exxua (TN) |
(P) Enzyme: CYP3A4 |
| D04338 |
Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride; Sekicode (TN) |
(P) unclassified |
| D04340 |
Dextromethorphan hydrobromide and potassium cresolsulfonate; Medicon (TN) |
(P) Enzyme: CYP3A4 |
| D04370 |
Granisetron (JAN/USAN/INN); Sancuso (TN) |
(P) Enzyme: CYP3A4 |
| D04446 |
Betamethasone acetate and betamethasone sodium phosphate; Celestone soluspan (TN); Rinderon (TN) |
(P) Enzyme: CYP3A4 |
| D04447 |
Betamethasone and d-chlorpheniramine maleate; Celestamine (TN) |
(P) Enzyme: CYP3A4 |
| D04461 |
Hydrocodone polistirex (USAN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D04463 |
Norgestrel and ethinylestradiol tablets (JP18); Low-ogestrel (TN); Planovar (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04645 |
Ixabepilone (JAN/USAN/INN); Ixempra (TN) |
(P) Enzyme: CYP3A4 |
| D04649 |
Ketazocine (USAN/INN); Ketocyclazocine |
(P) unclassified |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D04681 |
Lazabemide (USAN/INN) |
(P) unclassified |
| D04716 |
Levomethadyl acetate (USAN); Levacetylmethadol (INN) |
(P) Enzyme: CYP3A4 |
| D04764 |
Lofentanil oxalate (USAN) |
(P) unclassified |
| D04768 |
Lonafarnib (JAN/USAN/INN); Zokinvy (TN) |
(P) unclassified |
| D04813 |
Lidocaine hydrochloride and epinephrine bitartrate; Lidocaine hydrochloride and adrenaline bitartrate; Ora (TN); Lidosite (TN) |
(P) Enzyme: CYP3A4 |
| D04820 |
Lurasidone hydrochloride (JAN/USAN); SM 13496; Latuda (TN) |
(P) Enzyme: CYP3A4 |
| D04859 |
Maribavir (JAN/USAN/INN); Camvia (TN); Livtencity (TN) |
(P) Enzyme: CYP3A4 |
| D04924 |
Meptazinol hydrochloride (USAN) |
(P) unclassified |
| D04965 |
Perphenazine hydrochloride; Perphenazine dihydrochloride; PZC intramuscular injection (TN) |
(P) unclassified |
| D04973 |
Methadyl acetate (USAN); Acetylmethadol (INN) |
(P) unclassified |
| D04985 |
Methohexital (USP/INN) |
(P) Target: GABRA1 |
| D05000 |
Methylprednisolone hemisuccinate (USP); Methylprednisolone succinate (JP18) |
(P) Enzyme: CYP3A4 |
| D05001 |
Methylprednisolone sodium phosphate (USAN) |
(P) Enzyme: CYP3A4 |
| D05002 |
Methylprednisolone suleptanate (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D05024 |
Mibefradil dihydrochloride (USAN); Posicor (TN) |
(P) unclassified |
| D05028 |
Midazolam maleate (USAN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D05029 |
Midostaurin (JAN/USAN/INN); Rydapt (TN) |
(P) Enzyme: CYP3A4 |
| D05033 |
Milacemide hydrochloride (USAN) |
(P) unclassified |
| D05039 |
Minaprine (USAN/INN); Cantor (TN) |
(P) unclassified |
| D05040 |
Minaprine hydrochloride (USAN) |
(P) unclassified |
| D05048 |
Mirfentanil hydrochloride (USAN) |
(P) unclassified |
| D05152 |
Netupitant (USAN/INN) |
(P) unclassified |
| D05154 |
Nexeridine hydrochloride (USAN) |
(P) unclassified |
| D05217 |
Ocfentanil hydrochloride (USAN) |
(P) unclassified |
| D05259 |
Omeprazole magnesium (USP); Prilosec OTC (TN) |
(P) Enzyme: CYP2C19 |
| D05261 |
Omeprazole sodium injection (JAN); Omeprazole sodium hydrate; Omepral (TN) |
(P) Enzyme: CYP2C19 |
| D05312 |
Oxycodone (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D05333 |
Paclitaxel poliglumex (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D05343 |
Palonosetron hydrochloride (JAN/USP); Aloxi (TN) |
(P) Enzyme: CYP3A4 |
| D05351 |
Josamycin propionate (JP18); Josamy (TN) |
(P) CYP inhibition: CYP3A4 |
| D05353 |
Pantoprazole (USAN/INN) |
(P) Enzyme: CYP2C19 |
| D05366 |
Procaterol hydrochloride hydrate (JP18); Meptin (TN) |
(P) Enzyme: CYP3A4 |
| D05462 |
Oxycodone hydrochloride hydrate (JP18) |
(P) Enzyme: CYP3A4 |
| D05538 |
Mozenavir (INN) |
(CI) unclassified |
| D05632 |
Propoxyphene napsylate (USAN); Darvon-N (TN) |
(P) unclassified |
| D05681 |
Quinine ascorbate (USAN); Quinine biascorbate |
(P) Enzyme: CYP3A4 |
| D05699 |
Ranitidine bismuth citrate (USAN); Tritec (TN) |
(P) unclassified |
| D05744 |
Roflumilast (JAN/USAN/INN); Daliresp (TN); Zoryve (TN) |
(P) Enzyme: CYP3A4 |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D05792 |
Salmeterol (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D05928 |
Stiripentol (JAN/USAN/INN); Diacomit (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP3A4 CYP2C19 |
| D05938 |
Sufentanil (USAN/INN) |
(P) unclassified |
| D05987 |
Synthetic conjugated estrogens, B (USAN); Enjuvia (TN) |
(P) Enzyme: CYP3A4 |
| D06007 |
Tapentadol (USAN/INN) |
(P) unclassified |
| D06068 |
Temsirolimus (JAN/USAN/INN); Torisel (TN) |
(P) Enzyme: CYP3A4 |
| D06106 |
Thiamylal |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D06147 |
Tilidine hydrochloride (USAN); Valoron (TN) |
(P) unclassified |
| D06199 |
Trabectedin (JAN/USAN/INN); Yondelis (TN) |
(P) Enzyme: CYP3A4 |
| D06208 |
Trefentanil hydrochloride (USAN) |
(P) unclassified |
| D06268 |
Trimeperidine (INN) |
(P) unclassified |
| D06273 |
Imidafenacin (JAN/INN); Uritos (TN); Staybla (TN) |
(P) Enzyme: CYP3A4 |
| D06315 |
Fluticasone furoate (JAN/USAN/INN); Veramyst (TN) |
(P) Enzyme: CYP3A4 |
| D06342 |
Xorphanol mesylate (USAN) |
(P) unclassified |
| D06402 |
Sunitinib malate (JAN/USAN); Sutent (TN) |
(P) Enzyme: CYP3A4 |
| D06405 |
Nalfurafine hydrochloride (JAN/USAN) |
(P) Enzyme: CYP3A4 |
| D06407 |
Vandetanib (JAN/USAN/INN); Caprelsa (TN) |
(P) Enzyme: CYP3A4 |
| D06412 |
Aliskiren fumarate (JAN/USAN); Aliskiren hemifumarate; Tekturna (TN) |
(P) Enzyme: CYP3A4 |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 |
| D06478 |
Darunavir ethanolate (JAN); Prezista (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D06499 |
Opium tincture (JP18); Opium tincture (TN) |
(P) unclassified |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D06670 |
Maraviroc (JAN/INN); Selzentry (TN) |
(P) Enzyme: CYP3A4 |
| D06887 |
Talbutal (INN); Lotusate (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D07065 |
Acepromazine (INN); Concentrat vo34 (TN) |
(P) unclassified |
| D07073 |
Dexamethasone cipecilate (JAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07086 |
Rivaroxaban (JAN/USAN/INN); Xarelto (TN) |
(P) Enzyme: CYP3A4 |
| D07113 |
Loperamide oxide (INN) |
(P) Enzyme: CYP3A4 |
| D07122 |
Alfentanil (INN); Rapifen (TN) |
(P) unclassified |
| D07124 |
Alfuzosin (INN); Xatral (TN) |
(P) Enzyme: CYP3A4 |
| D07129 |
Alosetron (INN) |
(P) unclassified |
| D07132 |
Buprenorphine (JAN/INN); Temgesic (TN) |
(P) Enzyme: CYP3A4 |
| D07165 |
Ivabradine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D07175 |
Palonosetron (INN); Aloxi (TN) |
(P) Enzyme: CYP3A4 |
| D07203 |
Methylprednisolone aceponate (INN); Advantan (TN) |
(P) Enzyme: CYP3A4 |
| D07226 |
Fesoterodine (INN) |
(P) Enzyme: CYP3A4 |
| D07283 |
Esketamine (USAN/INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D07285 |
Nicomorphine (INN) |
(P) unclassified |
| D07286 |
Diamorphine (BAN); Heroin; Diacetylmorphine |
(P) unclassified |
| D07287 |
Dextromoramide (BAN) |
(P) unclassified |
| D07288 |
Piritramide (INN); Dipidolor (TN) |
(P) unclassified |
| D07289 |
Bezitramide (INN); Burgodin (TN) |
(P) unclassified |
| D07298 |
Barbexaclone (INN); Maliasin (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D07299 |
Lacosamide (JAN/USAN/INN); Erlosamide; Vimpat (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP2C19 |
| D07307 |
Cyamemazine (INN); Tercian (TN) |
(P) unclassified |
| D07308 |
Chlorproethazine (INN) |
(P) unclassified |
| D07321 |
Vinylbital (INN); Vinylbitone |
(P) unclassified |
| D07322 |
Vinbarbital (INN) |
(P) unclassified |
| D07323 |
Cyclobarbital (INN); Ciclobarbital (TN) |
(P) unclassified |
| D07324 |
Proxibarbal (INN); Centralgol (TN) |
(P) unclassified |
| D07337 |
Nialamide (INN); Niamid (TN) |
(P) unclassified |
| D07338 |
Iproclozide (INN); Iproclozide (TN) |
(P) unclassified |
| D07402 |
Levocetirizine (USAN/INN); Xazal (TN) |
(P) Enzyme: CYP3A4 |
| D07407 |
Rupatadine (INN) |
(P) Enzyme: CYP3A4 |
| D07435 |
Papaveretum (BAN); Omnopon (TN) |
(P) unclassified |
| D07448 |
Amitriptyline (INN); Laroxyl (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D07450 |
Amlodipine (USP/INN); Norvasc (TN) |
(P) Enzyme: CYP3A4 |
| D07471 |
Atazanavir (INN); Reyataz (TN) |
(CI,P) CYP inhibition: CYP3A4 |
| D07474 |
Atorvastatin (INN); Lipitor (TN); Sortis (TN) |
(P) Enzyme: CYP3A4 |
| D07494 |
Barnidipine (INN); Vasexten (TN) |
(P) Enzyme: CYP3A4 |
| D07509 |
Benidipine (INN) |
(P) Enzyme: CYP3A4 |
| D07520 |
Bepridil (INN); Bepadin (TN) |
(P) Enzyme: CYP3A4 |
| D07523 |
Betaine (JAN); Cystadane (TN) |
(P) unclassified |
| D07538 |
Bosentan (INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07552 |
Bupivacaine (USAN/INN); Bucaine (TN); Exparel (TN) |
(P) Enzyme: CYP3A4 |
| D07569 |
Candesartan cilexetil and anmlodipine besylate (JP18); Unisia (TN) |
(P) Enzyme: CYP3A4 |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) unclassified |
| D07585 |
Isopropylantipyrine, ergotamine tartrate and anhydrous caffeine; Cleamine A (TN) |
(P) Enzyme: CYP3A4 |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) CYP induction: CYP3A4 |
| D07603 |
Caffeine citrate (USP); Cafcit (TN) |
(P) unclassified |
| D07620 |
Carfentanil (INN) |
(P) unclassified |
| D07661 |
Cerivastatin (INN) |
(P) Enzyme: CYP3A4 |
| D07667 |
Cevimeline (INN) |
(P) Enzyme: CYP3A4 |
| D07685 |
Chlorproethazine hydrochloride; Neuriplege (TN) |
(P) unclassified |
| D07702 |
Ciprofloxacin lactate; Ciproxin (TN) |
(P) unclassified |
| D07704 |
Citalopram (USP/INN); Citadur (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2C19 |
| D07705 |
Citalopram hydrochloride; Seropram (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2C19 |
| D07710 |
Clarithromycin lactobionate; Klacid (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D07727 |
Clomipramine (INN); Anafranil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D07729 |
Clopidogrel (USP/INN); Clopidogrel (TN); Plavix (TN) |
(P) Enzyme: CYP2C19 |
| D07740 |
Codeine hydrochloride; Bisoltus (TN) |
(P) unclassified |
| D07748 |
Conivaptan (INN) |
(P) unclassified |
| D07756 |
Cyamemazine tartrate; Tercian (TN) |
(P) unclassified |
| D07757 |
Cyclobarbital calcium (BAN); Phanodorn calcium (TN) |
(P) unclassified |
| D07760 |
Cyclophosphamide (INN); Cyclophosphamide (TN); Cytoxan (TN) |
(P) Enzyme: CYP3A4 |
| D07782 |
Delavirdine (INN) |
(P) unclassified |
| D07793 |
Desvenlafaxine (INN); Khedezla (TN) |
(P) Enzyme: CYP3A4 |
| D07796 |
Dexamethasone 21-acetate; Dexamethasone acetate anhydrous; Decaject-L.A. (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07797 |
Dexamethasone isonicotinate; Dexamethasone 21-isonicotinate; Voren [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07798 |
Dexamethasone sodium hemisulfate; Dexamethasone 21-sodium sulfate; Colircusi Dexametasona (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07799 |
Dexamethasone 21-tebutate; Dexamethasone tertiary butyl acetate; Dexamedium [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07800 |
Dexamethasone 21-valerate; Voalla (TN); Zalucs (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07801 |
Dexamethasone phenylpropionate; Dexafort [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07802 |
Dexamethasone phosphate; Decadron-phosphate (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07808 |
Dextromoramide tartrate; Palfium (TN) |
(P) unclassified |
| D07809 |
Dextropropoxyphene (INN); Propoxypene |
(P) unclassified |
| D07810 |
Diacetylmorphine hydrochloride; Diamorphine hydrochloride; Heroin hydrochloride; Diamorphine (TN) |
(P) unclassified |
| D07831 |
Dihydrocodeine (INN); Remedacen (TN) |
(P) unclassified |
| D07832 |
Dihydrocodeine thiocyanate; Paracodin (TN) |
(P) unclassified |
| D07837 |
Dihydroergotamine (INN); Neomigran (TN) |
(P) Enzyme: CYP3A4 |
| D07838 |
Dihydroergotamine tartrate; Divegal (TN) |
(P) Enzyme: CYP3A4 |
| D07839 |
Dihydroergotoxine; Co-Dergocrin (TN) |
(P) Enzyme: CYP3A4 |
| D07845 |
Diltiazem (INN); Surazem (TN) |
(P) Enzyme: CYP3A4 |
| D07865 |
Dixyrazine; Esucos (TN) |
(P) unclassified |
| D07866 |
Docetaxel (JAN/INN); Docetaxel (TN); Taxotere (TN) |
(P) Enzyme: CYP3A4 |
| D07868 |
Domperidone maleate; Domperidone (TN) |
(P) Enzyme: CYP3A4 |
| D07869 |
Donepezil (JAN/INN); Donaz (TN); Allydone (TN) |
(P) Enzyme: CYP3A4 |
| D07871 |
Dorzolamide (INN); Trusopt (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D07873 |
Doxapram (INN); Docatone (TN) |
(P) Enzyme: CYP3A4 |
| D07887 |
Eletriptan (INN) |
(P) Enzyme: CYP3A4 |
| D07904 |
Eptazocine (INN) |
(P) unclassified |
| D07905 |
Ergometrine (INN) |
(P) Enzyme: CYP3A4 |
| D07906 |
Ergotamine (INN) |
(P) Enzyme: CYP3A4 |
| D07907 |
Erlotinib (INN) |
(P) Enzyme: CYP3A4 |
| D07909 |
Erythromycin thiocyanate; Erythrocin (TN) |
(P) unclassified |
| D07910 |
Erythromycin stinoprate (INN); Erysec (TN) |
(P) unclassified |
| D07913 |
Escitalopram (INN); Esertia (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D07917 |
Esomeprazole (INN); Inexium paranova (TN) |
(P) Enzyme: CYP2C19 |
| D07918 |
Estradiol hemihydrate; Estrasorb (TN); Vagifem (TN) |
(P) Enzyme: CYP3A4 |
| D07919 |
Estradiol 17 beta-hemisuccinate; 17beta-Estradiol hemisuccinate; Eutocol (TN) |
(P) Enzyme: CYP3A4 |
| D07928 |
Ethinylestradiol propanesulfonate; Turisteron (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D07929 |
Ethylmorphine (BAN) |
(P) Enzyme: CYP3A4 |
| D07937 |
Etorphine (INN) |
(P) unclassified |
| D07945 |
Fenfluramine (INN); Ponderax (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D07977 |
Fluphenazine (INN); Moditen (TN) |
(P) unclassified |
| D07981 |
Fluticasone (INN); Fluticaps (TN) |
(P) Enzyme: CYP3A4 |
| D07983 |
Fluvastatin (INN); Fluvas (TN) |
(P) Enzyme: CYP3A4 |
| D07984 |
Fluvoxamine (INN) |
(P) CYP inhibition: CYP2C19 CYP3A4 |
| D08031 |
Guanfacine (INN); Estulic (TN) |
(P) Enzyme: CYP3A4 |
| D08035 |
Haloperidol lactate; Haldol (TN) |
(P) Enzyme: CYP3A4 |
| D08045 |
Hydrocodone (INN); Dihydrocodeinone |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08046 |
Hydrocodone hydrochloride; Dihydrocodeinone hydrochloride; Dicodid (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08047 |
Hydromorphone (INN) |
(P) unclassified |
| D08050 |
Hydroxychloroquine (INN); Polirreumin (TN) |
(P) Enzyme: CYP3A4 |
| D08066 |
Imatinib (INN); Glamox (TN) |
(P) Enzyme: CYP3A4 |
| D08070 |
Imipramine (INN); Tofranil (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08071 |
Imipramine pamoate (USP); Imipramine embonate; Tofranil-pm (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08085 |
Iproniazid phosphate; Marsilid (TN) |
(P) unclassified |
| D08086 |
Irinotecan (INN); Biotecan (TN) |
(P) unclassified |
| D08095 |
Ivabradine hydrochloride (JAN/USAN); Ivabrandine hydrochloride; Corlanor (TN); Corlentor (TN); Coralan (TN) |
(P) Enzyme: CYP3A4 |
| D08100 |
Ketobemidone (INN) |
(P) unclassified |
| D08101 |
Ketobemidone hydrochloride; Ketogan (TN) |
(P) unclassified |
| D08108 |
Lapatinib (INN) |
(P) Enzyme: CYP3A4 |
| D08116 |
Levobupivacaine (INN); Novabupi (TN) |
(P) Enzyme: CYP3A4 |
| D08118 |
Levocetirizine dihydrochloride (USP); Levocetirizine hydrochloride (JAN); Xyzal (TN) |
(P) Enzyme: CYP3A4 |
| D08121 |
Levomethadone (INN) |
(P) unclassified |
| D08122 |
Levomethadone hydrochloride; L-polamidon (TN) |
(P) unclassified |
| D08123 |
Levorphanol (INN) |
(P) unclassified |
| D08127 |
Lidocaine hydrochloride monohydrate; Lidocaine (TN); Zingo (TN) |
(P) Enzyme: CYP3A4 |
| D08144 |
Loperamide (INN); Diamide (TN) |
(P) Enzyme: CYP3A4 |
| D08148 |
Loxapine hydrochloride; Desconex (TN) |
(P) Enzyme: CYP3A4 |
| D08155 |
Manidipine (INN); Manidipine 6300; Artedil (TN) |
(P) Enzyme: CYP3A4 |
| D08182 |
Meptazinol (INN) |
(P) unclassified |
| D08195 |
Methadone (BAN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP induction: CYP3A4 |
| D08207 |
Methylergometrine (INN); Ergotyl (TN) |
(P) Enzyme: CYP3A4 |
| D08216 |
Mianserin (INN); Tolvon (TN) |
(P) Enzyme: CYP3A4 |
| D08217 |
Mibefradil (INN) |
(P) unclassified |
| D08227 |
Mometasone (INN) |
(P) Enzyme: CYP3A4 |
| D08229 |
Montelukast (INN); Brondilat (TN) |
(P) Enzyme: CYP3A4 |
| D08233 |
Morphine (BAN); Morfina Dosa (TN); Substitol (TN) |
(P) unclassified |
| D08234 |
Morphine tartrate; Morphine Tartrate (TN) |
(P) unclassified |
| D08236 |
Mosapride (INN); Mosart (TN) |
(P) Enzyme: CYP3A4 |
| D08246 |
Nalbuphine (INN); Intapan (TN) |
(P) unclassified |
| D08255 |
Naratriptan (INN); Naramig (TN) |
(P) Enzyme: CYP3A4 |
| D08259 |
Nelfinavir (INN); Viracept (TN) |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08270 |
Nicardipine (INN); Cardene (TN) |
(P) Enzyme: CYP3A4 |
| D08273 |
Nicomorphine hydrochloride; Vilan (TN) |
(P) unclassified |
| D08283 |
Nordazepam (INN); Calmday (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D08287 |
Norfloxacin nicotinate; Quinabic soluble powder (TN) [veterinary] |
(P) unclassified |
| D08291 |
Ofloxacin hydrochloride; Tarivid (TN) |
(P) Enzyme: CYP3A4 |
| D08323 |
Oxymorphone (INN) |
(P) unclassified |
| D08341 |
Perphenazine decanoate; Trilafon dekanoat (TN) |
(P) unclassified |
| D08342 |
Perphenazine enantate; Perphenazine enanthate; Trilafon (TN) |
(P) unclassified |
| D08343 |
Pethidine (INN); Meperidine; Pethidine DBL (TN) |
(P) unclassified |
| D08349 |
Phenelzine (BAN) |
(P) unclassified |
| D08356 |
Phenobarbital diethylamine; Gratusminal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D08385 |
Pipotiazine (INN); Piportil (TN) |
(P) unclassified |
| D08392 |
Pirlindole (INN); Pyrazidol (TN) |
(P) unclassified |
| D08393 |
Pirlindole hydrochloride; Implementor (TN) |
(P) unclassified |
| D08408 |
Pranlukast (INN); Azlaire (TN) |
(P) Enzyme: CYP3A4 |
| D08424 |
Procaterol (INN); Meptin (TN) |
(P) Enzyme: CYP3A4 |
| D08430 |
Promazine (INN); Combelen [veterinary] (TN) |
(P) unclassified |
| D08435 |
Propafenone (INN); Propafenon hexal (TN) |
(P) Enzyme: CYP3A4 |
| D08441 |
Propiverine (INN) |
(P) Enzyme: CYP3A4 |
| D08453 |
Pargyline (INN) |
(P) unclassified |
| D08456 |
Quetiapine (INN); Norsic (TN) |
(P) Enzyme: CYP3A4 |
| D08460 |
Quinine (BAN); Kinder Quinina (TN) |
(P) Enzyme: CYP3A4 |
| D08461 |
Quinine dihydrochloride; Quinine (TN) |
(P) Enzyme: CYP3A4 |
| D08463 |
Rabeprazole (INN); Eraloc (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08469 |
Rasagiline (USAN/INN); Azilect (TN) |
(P) unclassified |
| D08473 |
Remifentanil (INN); Ultiva (TN) |
(P) unclassified |
| D08479 |
Rifampicin sodium; Rifadine (TN) |
(P) CYP induction: CYP3A4 |
| D08481 |
Rilmazafone (INN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D08488 |
Amlodipine besilate and atorvastatin calcium; Caduet (TN) |
(P) Enzyme: CYP3A4 |
| D08490 |
Ropivacaine (INN); Naropin (TN) |
(P) Enzyme: CYP3A4 |
| D08493 |
Dorzolamide hydrochloride and timolol maleate (JP18); Cosopt (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08497 |
Rupatadine fumarate (JAN); Rinialer (TN); Rupafin (TN) |
(P) Enzyme: CYP3A4 |
| D08508 |
Sarpogrelate (INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D08514 |
Sildenafil (INN); Aphrodil (TN) |
(P) Enzyme: CYP3A4 |
| D08522 |
Solifenacin (INN) |
(P) Enzyme: CYP3A4 |
| D08552 |
Sunitinib (INN) |
(P) Enzyme: CYP3A4 |
| D08556 |
Tacrolimus (INN); Prograf (TN) |
(P) Enzyme: CYP3A4 |
| D08559 |
Tamoxifen (INN); Tamoxifen (TN); Tamoplex (TN) |
(P) Enzyme: CYP3A4 |
| D08575 |
Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
(P) unclassified |
| D08585 |
Thioproperazine (INN) |
(P) unclassified |
| D08597 |
Tilidine (INN) |
(P) unclassified |
| D08605 |
Tipranavir (INN); Aptivus (TN) |
(CI) unclassified |
| D08616 |
Teneligliptin (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08620 |
Toremifene (INN); Fareston (TN) |
(P) Enzyme: CYP3A4 |
| D08623 |
Tramadol (INN); Amanda (TN) |
(P) Enzyme: CYP3A4 |
| D08625 |
Tranylcypromine (INN); Parnate (TN) |
(P) unclassified |
| D08626 |
Trazodone (INN); Trittico (TN) |
(P) Enzyme: CYP3A4 |
| D08636 |
Trifluoperazine (INN); Apo-trifluoperazine (TN) |
(P) unclassified |
| D08668 |
Vardenafil (USAN/INN); Levitra (TN) |
(P) Enzyme: CYP3A4 |
| D08670 |
Venlafaxine (INN); Efectin (TN) |
(P) unclassified |
| D08675 |
Vinblastine (INN); Vinblastina (TN) |
(P) Enzyme: CYP3A4 |
| D08680 |
Vinorelbine (INN); Navelbine (TN) |
(P) Enzyme: CYP3A4 |
| D08690 |
Zolpidem (INN); Sanval (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D08695 |
dl-Methylephedrine hydrochloride, dihydrocodeine phosphate, diprophylline, diphenhydramine salicylate, acetaminophen and bromovalerylurea; Coughcode N (TN) |
(P) unclassified |
| D08697 |
Platycodon fluidextract, glycyrrhiza extract, plantago herb extract, peony root extract and dihydrocodeine phosphate; Opisezol codeine (TN) |
(P) unclassified |
| D08699 |
Salmeterol xinafoate and fluticasone propionate; Adoair diskus (TN); Aerivio Spiromax (TN) |
(P) Enzyme: CYP3A4 |
| D08774 |
Amoxicillin hydrate, clarithromycin and lansoprazole; Lansap (TN); Prevpac (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP3A4 |
| D08837 |
Aclidinium bromide (JAN/USAN/INN); Tudorza pressair (TN); Eklira genuair (TN) |
(P) CYP inhibition: CYP3A4 |
| D08856 |
Anamorelin hydrochloride (JAN/USAN); Adlumiz (TN) |
(P) Enzyme: CYP3A4 |
| D08870 |
Belinostat (USAN/INN); Beleodaq (TN) |
(P) Enzyme: CYP3A4 |
| D08876 |
Boceprevir (INN/USAN); Victrelis (TN) |
(P) unclassified |
| D08903 |
Dexlansoprazole (INN/USAN); Dexilant (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP2C19 |
| D08914 |
Eribulin mesylate (USAN); Eribulin mesilate (JAN); Halaven (TN) |
(P) Enzyme: CYP3A4 |
| D08923 |
Fesoterodine fumarate (JAN/USAN); Toviaz (TN) |
(P) Enzyme: CYP3A4 |
| D08950 |
Neratinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D08953 |
Nilotinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D08969 |
Pimavanserin tartrate (USAN); Nuplazide (TN) |
(P) Enzyme: CYP3A4 |
| D08976 |
Pomalidomide (JAN/USAN/INN); Pomalyst (TN) |
(P) Enzyme: CYP3A4 |
| D08988 |
Rolapitant hydrochloride (USAN); Varubi (TN) |
(P) Enzyme: CYP3A4 |
| D08996 |
Saxagliptin (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09012 |
Telaprevir (JAN/USAN/INN); Incivek (TN); Incivo (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D09017 |
Ticagrelor (JAN/USAN/INN); Brilinta (TN) |
(P) unclassified |
| D09033 |
Voclosporin (JAN/USAN/INN); Lupkynis (TN) |
(P) Enzyme: CYP3A4 |
| D09187 |
Estradiol and levonorgestrel; Wellnara (TN); Climara pro (TN) |
(P) Enzyme: CYP3A4 |
| D09188 |
Estradiol and norethindrone; Menoaid (TN); Activella (TN); Combipatch (TN); Estradiol and norethindrone acetate (TN) |
(P) Enzyme: CYP3A4 |
| D09216 |
Thiopropazate (INN) |
(P) unclassified |
| D09318 |
Indacaterol (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09319 |
Indacaterol maleate (JAN/USAN); Arcapta neohaler (TN) |
(P) Enzyme: CYP3A4 |
| D09339 |
Esomeprazole potassium (USAN) |
(P) Enzyme: CYP2C19 |
| D09347 |
Fostamatinib (USAN) |
(P) Enzyme: CYP3A4 |
| D09348 |
Fostamatinib disodium (USAN); Fostamatinib sodium hydrate (JAN); Fostamatinib disodium hexahydrate; Tavalisse (TN) |
(P) Enzyme: CYP3A4 |
| D09365 |
Palovarotene (JAN/USAN/INN); Sohonos (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D09388 |
Tasimelteon (USAN/INN); Hetlioz (TN) |
(P) Enzyme: CYP3A4 |
| D09394 |
Fidaxomicin (JAN/USAN); Dificid (TN); Dificlir (TN) |
(P) CYP inhibition: CYP2C19 CYP3A4 |
| D09535 |
Mirabegron (JAN/USAN/INN); Myrbetriq (TN) |
(P) Enzyme: CYP3A4 |
| D09544 |
Ozenoxacin (JAN/USAN/INN); Xepi (TN) |
(P) Enzyme: CYP3A4 |
| D09594 |
Olmesartan medoxomil and azelnidipine; Rezaltas (TN) |
(P) Enzyme: CYP3A4 |
| D09595 |
Budesonide and formoterol fumarate dihydrate; Symbicort (TN); Budeforu (TN) |
(P) Enzyme: CYP3A4 |
| D09637 |
Lomitapide (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 |
| D09666 |
Selumetinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09683 |
Tivozanib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09698 |
Vilazodone (USAN/INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D09699 |
Vilazodone hydrochloride (USAN); Viibryd (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D09701 |
Abiraterone acetate (JAN/USP); Zytiga (TN) |
(P) Enzyme: CYP3A4 |
| D09728 |
Bosutinib hydrate (JAN); Bosutinib monohydrate; Bosulif (TN) |
(P) Enzyme: CYP3A4 |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 |
| D09741 |
Drospirenone and ethinylestradiol; Drospirenone and ethinylestradiol betadex; Angeliq (TN); Yaz (TN); Flexyess (TN) |
(P) Enzyme: CYP3A4 |
| D09742 |
Lansoprazole, amoxicillin hydrate and metronidazole; Lampion (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D09743 |
Telmisartan and amlodipine besilate (JP18); Telmisartan and amlodipine besylate; Micamlo (TN); Twynsta (TN) |
(P) Enzyme: CYP3A4 |
| D09745 |
Valsartan and amlodipine besilate; Exforge (TN) |
(P) Enzyme: CYP3A4 |
| D09753 |
Saxagliptin hydrate (JAN); Onglyza (TN) |
(P) Enzyme: CYP3A4 |
| D09756 |
Teneligliptin hydrobromide hydrate (JAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D09765 |
Vorapaxar (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09766 |
Vorapaxar sulfate (JAN/USAN); Zontivity (TN) |
(P) Enzyme: CYP3A4 |
| D09773 |
Isoniazid glucuronate sodium (JAN) |
(P) unclassified |
| D09783 |
Tofacitinib citrate (JAN/USAN); Tasocitinib citrate; Xeljanz (TN) |
(P) Enzyme: CYP3A4 |
| D09785 |
Delamanid (JAN/USAN); Deltyba (TN) |
(P) Enzyme: CYP3A4 |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09819 |
Chlorpromazine tannate (JAN) |
(P) unclassified |
| D09872 |
Bedaquiline (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09873 |
Bedaquiline fumarate (JAN/USAN); Sirturo (TN) |
(P) Enzyme: CYP3A4 |
| D09876 |
Cariprazine hydrochloride (JAN/USAN); Vraylar (TN) |
(P) Enzyme: CYP3A4 |
| D09881 |
Cobicistat (JAN/USAN/INN); Tybost (TN) |
(P) Enzyme-Target: CYP3A4 |
| D09893 |
Eliglustat (USAN/INN) |
(P) unclassified |
| D09894 |
Eliglustat tartrate (JAN/USAN); Eliglustat hemitartrate; Cerdelga (TN) |
(P) unclassified |
| D09959 |
Ruxolitinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09960 |
Ruxolitinib phosphate (JAN/USAN); Jakafi (TN); Jakavi (TN); Opzelura (TN) |
(P) Enzyme: CYP3A4 |
| D09970 |
Tofacitinib (USAN); Tasocitinib |
(P) Enzyme: CYP3A4 |
| D09989 |
Vardenafil hydrochloride (USP) |
(P) Enzyme: CYP3A4 |
| D09994 |
Selexipag (JAN/USAN/INN); Uptravi (TN) |
(P) Enzyme: CYP3A4 |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP induction: CYP3A4 |
| D09997 |
Cariprazine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D09999 |
Tramadol hydrochloride and acetaminophen; Tramcet (TN) |
(P) Enzyme: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 |
| D10012 |
Incobotulinumtoxin A (JAN/USAN); Onaclostox; Xeomin (TN) |
(P) unclassified |
| D10019 |
Panobinostat lactate (JAN); Farydak (TN) |
(P) Enzyme: CYP3A4 |
| D10024 |
Selumetinib sulfate (JAN/USAN); Koselugo (TN) |
(P) Enzyme: CYP3A4 |
| D10064 |
Dabrafenib (USAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10065 |
Daclatasvir (USAN) |
(P) Enzyme: CYP3A4 |
| D10066 |
Dolutegravir (USAN); Tivicay (TN) |
(P) unclassified |
| D10081 |
Simeprevir (JAN/USAN) |
(P) unclassified |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10105 |
Daclatasvir dihydrochloride (USAN); Daclatasvir hydrochloride (JAN); Daklinza (TN) |
(P) Enzyme: CYP3A4 |
| D10113 |
Dolutegravir sodium (JAN/USAN); Tivicay (TN) |
(P) unclassified |
| D10120 |
Esomeprazole strontium (USAN); Esomeprazole strontium tetrahydrate; Esomeprazole strontium (TN) |
(P) Enzyme: CYP2C19 |
| D10135 |
Macitentan (JAN/USAN); Opsumit (TN) |
(P) Enzyme: CYP3A4 |
| D10137 |
Regorafenib hydrate (JAN); Stivarga (TN) |
(P) Enzyme: CYP3A4 |
| D10138 |
Regorafenib (USAN/INN); Stivarga (TN) |
(P) Enzyme: CYP3A4 |
| D10158 |
Safinamide (USAN/INN) |
(P) unclassified |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10184 |
Vortioxetine (USAN); Brintellix (TN) |
(P) Enzyme: CYP2C19 |
| D10185 |
Vortioxetine hydrobromide (JAN/USAN); Brintellix (TN); Trintellix (TN) |
(P) Enzyme: CYP2C19 |
| D10188 |
Naldemedine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10190 |
Tivozanib hydrochloride (USAN); Tivozanib hydrochloride monohydrate; Fotivda (TN) |
(P) Enzyme: CYP3A4 |
| D10191 |
Safinamide mesylate (USAN); Safinamide mesilate (JAN); Safinamide methanesulfonate; Xadago (TN); Equfina (TN) |
(P) unclassified |
| D10194 |
Remimazolam besylate (USAN); Remimazolam besilate (JAN); Anerem (TN); Byfavo (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D10199 |
Tapentadol hydrochloride (JAN); Nucynta (TN) |
(P) unclassified |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10243 |
Irbesartan and amlodipine besilate (JP18); Aimix (TN) |
(P) Enzyme: CYP3A4 |
| D10246 |
Omeprazole, clarithromycin and amoxicillin; Omeclamox-pak (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP3A4 |
| D10262 |
Saxagliptin hydrochloride; Onglyza (TN) |
(P) Enzyme: CYP3A4 |
| D10263 |
Metformin hydrochloride and saxagliptin hydrochloride; Kombiglyze (TN) |
(P) Enzyme: CYP3A4 |
| D10306 |
Avatrombopag (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10307 |
Avatrombopag maleate (JAN/USAN); Doptelet (TN) |
(P) Enzyme: CYP3A4 |
| D10309 |
Brexpiprazole (JAN/USAN/INN); Rexulti (TN) |
(P) Enzyme: CYP3A4 |
| D10315 |
Momelotinib (USAN/INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10319 |
Panobinostat (USAN/INN); Farydak (TN) |
(P) Enzyme: CYP3A4 |
| D10355 |
Aripiprazole cavoxil (USAN) |
(P) Enzyme: CYP3A4 |
| D10358 |
Momelotinib dihydrochloride (USAN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10364 |
Aripiprazole lauroxil (USAN); Aristada (TN) |
(P) Enzyme: CYP3A4 |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10385 |
Ezetimibe and atorvastatin; Atozet (TN); Liptruzet (TN) |
(P) Enzyme: CYP3A4 |
| D10433 |
Vibegron (JAN/USAN/INN); Beova (TN); Gemtesa (TN) |
(P) Enzyme: CYP3A4 |
| D10450 |
Alectinib hydrochloride (JAN); Alecensa (TN) |
(P) Enzyme: CYP3A4 |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10469 |
Simeprevir sodium (JAN); Olysio (TN); Sovriad (TN) |
(P) unclassified |
| D10478 |
Naldemedine tosylate (JAN/USAN); Naldemedine tosilate; Symproic (TN) |
(P) Enzyme: CYP3A4 |
| D10501 |
Fluticasone furoate and vilanterol trifenatate; Breo ellipta (TN); Relvar ellipita (TN) |
(P) Enzyme: CYP3A4 |
| D10505 |
Glycopyrronium bromide and indacaterol maleate; Ultibro (TN) |
(P) Enzyme: CYP3A4 |
| D10506 |
Fluticasone propionate and formoterol fumarate hydrate; Flutiform (TN) |
(P) Enzyme: CYP3A4 |
| D10512 |
Brinzolamide and timolol maleate; Azorga (TN) |
(P) Enzyme: CYP3A4 |
| D10513 |
Clopidogrel sulfate and aspirin; Clopidogrel and acetylsalicyclic acid; Complavin (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10516 |
Aripiprazole hydrate (JAN); Aripiprazole monohydrate; Abilify maintena (TN) |
(P) Enzyme: CYP3A4 |
| D10519 |
Rabeprazole, amoxicillin and clarithromycin; Rabecure (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP3A4 |
| D10520 |
Rabeprazole, amoxicillin and metronidazole; Rabefine (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10524 |
Azilsartan and amlodipine besilate; Zacras (TN) |
(P) Enzyme: CYP3A4 |
| D10525 |
Valsartan and cilnidipine; Atedio (TN) |
(P) Enzyme: CYP3A4 |
| D10527 |
Acetylsalicylic acid and lansoprazole; Acetylsalicylic acid and lansoprazole; Takelda (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10533 |
Umeclidinium bromide and vilanterol; Anoro (TN) |
(P) Enzyme: CYP3A4 |
| D10542 |
Alectinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) unclassified |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10572 |
Fosnetupitant and palonosetron hydrochloride; Netupitant and palonosetron hydrochloride; Akynzeo (TN) |
(P) Enzyme: CYP3A4 |
| D10582 |
Dasabuvir, ombitasvir, paritaprevir and ritonavir; Viekira pak (TN) |
(P) CYP inhibition: CYP3A4 |
| D10600 |
Dolutegravir, abacavir and lamivudine; Triumeq (TN) |
(P) unclassified |
| D10612 |
Benzhydrocodone (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10627 |
Esketamine hydrochloride (JAN/USAN); Spravato (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10630 |
Fedratinib (USAN/INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10633 |
Finerenone (JAN/USAN/INN); Kerendia (TN) |
(P) Enzyme: CYP3A4 |
| D10639 |
Grazoprevir (USAN); Grazoprevir hydrate (JAN); Grazyna (TN) |
(P) unclassified |
| D10642 |
Irinotecan sucrosofate (USAN) |
(P) unclassified |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10644 |
Isavuconazonium (USAN) |
(P) unclassified |
| D10662 |
Rimegepant (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10663 |
Rimegepant sulfate (USAN); Nurtec odt (TN); Vydura (TN) |
(P) Enzyme: CYP3A4 |
| D10669 |
Sotagliflozin (USAN/INN); Inpefa (TN) |
(P) unclassified |
| D10673 |
Ubrogepant (USAN/INN); Ubrelvy (TN) |
(P) Enzyme: CYP3A4 |
| D10675 |
Valbenazine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10692 |
Benzhydrocodone hydrochloride (USAN) |
(P) Enzyme: CYP3A4 |
| D10696 |
Capmatinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10709 |
Gilteritinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10742 |
Rolapitant (USAN/INN); Varubi (TN) |
(P) Enzyme: CYP3A4 |
| D10745 |
Ombitasvir, paritaprevir and ritonavir; Technivie (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10749 |
Pitolisant (USAN/INN); Wakix (TN); Ozawade (TN) |
(P) unclassified |
| D10753 |
Atazanavir and cobicistat; Evotaz (TN) |
(P) Enzyme: CYP3A4 |
| D10755 |
Elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide; Genvoya (TN) |
(P) unclassified |
| D10756 |
Elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil; Stribild (TN) |
(P) unclassified |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP3A4 |
| D10800 |
Gilteritinib fumarate (JAN/USAN); Xospata (TN) |
(P) Enzyme: CYP3A4 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) CYP induction: CYP2C19 |
| D10805 |
Telmisartan, amlodipine and hydrochlorothiazide; Micatrio (TN) |
(P) Enzyme: CYP3A4 |
| D10811 |
Fentanyl hydrochloride (JAN); Ionsys (TN) |
(P) Enzyme: CYP3A4 |
| D10822 |
Ciprofloxacin hydrate (JAN); Ciprofloxacin hemiheptahydrate |
(P) unclassified |
| D10823 |
Clopidogrel hydrochloride; Clopidogrel (TN) |
(P) Enzyme: CYP2C19 |
| D10824 |
Clopidogrel besilate; Clopidogrel besylate; Clopidogrel (TN) |
(P) Enzyme: CYP2C19 |
| D10827 |
Sofosbuvir and velpatasvir; Epclusa (TN) |
(P) Enzyme: CYP3A4 |
| D10829 |
Rasagiline tartrate; Rasagiline (TN) |
(P) unclassified |
| D10832 |
Darunavir and cobicistat; Prezcobix (TN); Rezolsta (TN) |
(P) unclassified |
| D10866 |
Brigatinib (JAN/USAN); Alunbrig (TN) |
(P) Enzyme: CYP3A4 |
| D10883 |
Ribociclib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10889 |
Momelotinib hydrochloride hydrate (JAN); Momelotinib dihydrochloride monohydrate; Ojjaara (TN); Omjjara (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10891 |
Capmatinib hydrochloride (USAN); Capmatinib hydrochloride hydrate (JAN); Tabrecta (TN) |
(P) Enzyme: CYP3A4 |
| D10895 |
Fosaprepitant (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D10897 |
Teneligliptin and canagliflozin; Teneligliptin and canagliflozin; Canalia (TN) |
(P) Enzyme: CYP3A4 |
| D10898 |
Neratinib maleate; Nerlynx (TN) |
(P) Enzyme: CYP3A4 |
| D10915 |
Cannabidiol (USAN/INN); CBD; Epidiolex (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 |
| D10927 |
Erdafitinib (JAN/USAN/INN); Balversa (TN) |
(P) Enzyme: CYP3A4 |
| D10930 |
Etrasimod (USAN) |
(P) Enzyme: CYP3A4 |
| D10931 |
Etrasimod arginine (USAN); Etrasimod L-arginine (JAN); Velsipity (TN) |
(P) Enzyme: CYP3A4 |
| D10954 |
Mirvetuximab soravtansine (USAN/INN); Mirvetuximab soravtansine-gynx; Elahere (TN) |
(P) Enzyme: CYP3A4 |
| D10960 |
Nirogacestat (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10979 |
Ribociclib succinate (USAN); Kisqali (TN) |
(P) Enzyme: CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D10994 |
Upadacitinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D10995 |
Upadacitinib tartrate (USAN) |
(P) Enzyme: CYP3A4 |
| D10999 |
Valbenazine tosylate (USAN); Valbenazine tosilate (JAN); Valbenazine ditosylate; Ingrezza (TN); Dysval (TN) |
(P) Enzyme: CYP3A4 |
| D11000 |
Vamorolone (USAN/INN); Agamree (TN) |
(P) Enzyme: CYP3A4 |
| D11009 |
Indacaterol acetate (JAN) |
(P) Enzyme: CYP3A4 |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11022 |
Lemborexant (JAN/USAN/INN); Dayvigo (TN) |
(P) Enzyme: CYP3A4 |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 CYP2C19 |
| D11048 |
Upadacitinib hydrate (JAN); Upadacitinib hemihydrate; Rinvoq (TN) |
(P) Enzyme: CYP3A4 |
| D11053 |
Encorafenib (JAN/USAN/INN); Braftovi (TN) |
(P) Enzyme: CYP3A4 |
| D11056 |
Mirtazapine hydrate (JAN) |
(P) Enzyme: CYP3A4 |
| D11061 |
Osilodrostat (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11062 |
Osilodrostat phosphate (JAN/USAN); Isturisa (TN) |
(P) Enzyme: CYP3A4 |
| D11063 |
Evocalcet (JAN/INN); Orkedia (TN) |
(P) unclassified |
| D11072 |
Siponimod fumarate (USAN); Siponimod fumaric acid (JAN); Mayzent (TN) |
(P) unclassified |
| D11073 |
Tepotinib hydrochloride (USAN); Tepotinib hydrochloride hydrate (JAN); Tepmetko (TN) |
(P) Enzyme: CYP3A4 |
| D11093 |
Avacopan (JAN/USAN/INN); Tavneos (TN) |
(P) Enzyme: CYP3A4 |
| D11095 |
Atorvastatin calcium propylene glycol solvate |
(P) Enzyme: CYP3A4 |
| D11114 |
Esomeprazole magnesium dihydrate |
(P) Enzyme: CYP2C19 |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11150 |
Cenobamate (USAN/INN); Xcopri (TN) |
(P) Enzyme: CYP2C19 CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D11158 |
Leniolisib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11159 |
Leniolisib phosphate (USAN); Joenja (TN) |
(P) Enzyme: CYP3A4 |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11214 |
Oliceridine (USAN/INN); Olinvyk (TN) |
(P) unclassified |
| D11222 |
Selinexor (USAN/INN); Xpovio (TN) |
(P) Enzyme: CYP3A4 |
| D11252 |
Fexinidazole (USAN/INN); Fexinidazole (TN) |
(P) Enzyme: CYP3A4 |
| D11270 |
Pexidartinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11271 |
Pexidartinib hydrochloride (JAN/USAN); Turalio (TN) |
(P) Enzyme: CYP3A4 |
| D11296 |
Fedratinib hydrochloride (USAN); Fedratinib hydrochloride hydrate (JAN); Fedratinib dihydrochloride monohydrate; Inrebic (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D11313 |
Atogepant (USAN); Qulipta (TN); Aquipta (TN) |
(P) Enzyme: CYP3A4 |
| D11330 |
Voxelotor (USAN); Oxbryta (TN) |
(P) Enzyme: CYP3A4 |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11371 |
Capivasertib (JAN/USAN); Truqap (TN) |
(P) Enzyme: CYP3A4 |
| D11382 |
Darunavir, cobicistat, emtricitabine and tenofovir alafenamide; Symtuza (TN) |
(P) unclassified |
| D11389 |
Dutasteride and tamsulosin; Jalyn (TN) |
(P) Enzyme: CYP3A4 |
| D11403 |
Asciminib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11404 |
Asciminib hydrochloride (JAN/USAN); Scemblix (TN) |
(P) Enzyme: CYP3A4 |
| D11405 |
Prabotulinumtoxin A (USAN); PrabotulinumtoxinA-xvfs; Jeuveau (TN) |
(P) unclassified |
| D11406 |
Risdiplam (JAN/USAN/INN); Evrysdi (TN) |
(P) Enzyme: CYP3A4 |
| D11417 |
Pemigatinib (JAN/USAN/INN); Pemazyre (TN) |
(P) Enzyme: CYP3A4 |
| D11453 |
Nirogacestat hydrobromide (USAN); Ogsiveo (TN) |
(P) Enzyme: CYP3A4 |
| D11454 |
Repotrectinib (JAN/USAN); Augtyro (TN) |
(P) Enzyme: CYP3A4 |
| D11460 |
Siponimod (USAN/INN) |
(P) unclassified |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11490 |
Pitolisant hydrochloride (USAN); Wakix (TN) |
(P) unclassified |
| D11553 |
Lidocaine and tetracaine; Pliaglis (TN); Synera (TN) |
(P) unclassified |
| D11565 |
Grazoprevir (USAN/INN); Grazoprevir anhydrous |
(P) unclassified |
| D11572 |
Beclomethasone dipropionate monohydrate; Beconase aq (TN) |
(P) Enzyme: CYP3A4 |
| D11573 |
Oxycodone and ibuprofen |
(P) Enzyme: CYP3A4 |
| D11576 |
Naproxen and esomeprazole magnesium; Vimovo (TN) |
(P) Enzyme: CYP2C19 |
| D11616 |
Aspirin and omeprazole; Yosprala (TN) |
(P) Enzyme: CYP2C19 |
| D11617 |
Eletriptan hydrobromide monohydrate |
(P) Enzyme: CYP3A4 |
| D11619 |
Desvenlafaxine succinate anhydrous; Desvenlafaxine succinate (TN) |
(P) unclassified |
| D11628 |
Benzhydrocodone and acetaminophen; Apadaz (TN) |
(P) Enzyme: CYP3A4 |
| D11631 |
Lefamulin (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11632 |
Lefamulin acetate (USAN); Xenleta (TN) |
(P) Enzyme: CYP3A4 |
| D11652 |
Tenapanor (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11653 |
Tenapanor hydrochloride (JAN/USAN); Ibsrela (TN); Phozevel (TN); Xphozah (TN) |
(P) Enzyme: CYP3A4 |
| D11656 |
Azelastine hydrochloride and fluticasone propionate; Dymista (TN) |
(P) Enzyme: CYP3A4 |
| D11671 |
Elacestrant (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11672 |
Elacestrant hydrochloride (USAN); Elacestrant dihydrochloride; Orserdu (TN) |
(P) Enzyme: CYP3A4 |
| D11673 |
Berotralstat (USAN/INN) |
(P) CYP inhibition: CYP3A4 |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP3A4 |
| D11706 |
Omeprazole and sodium bicarbonate; Zegerid (TN) |
(P) Enzyme: CYP2C19 |
| D11710 |
Phentermine and topiramate; Qsymia (TN) |
(P) Enzyme: CYP3A4 |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 |
| D11717 |
Tepotinib (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11768 |
Pacritinib (USAN/INN); Vonjo (TN) |
(P) Enzyme: CYP3A4 |
| D11784 |
Vonoprazan (USAN/INN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D11793 |
Zuranolone (JAN/USAN/INN); Zurzuvae (TN) |
(P) Enzyme: CYP3A4 |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11851 |
Butalbital, acetaminophen, caffeine and codeine phosphate |
(P) unclassified |
| D11860 |
Butalbital, aspirin, caffeine and codeine; Fiorinal with codeine (TN) |
(P) Enzyme: CYP3A4 |
| D11881 |
Amlodipine benzoate; Katerzia (TN) |
(P) Enzyme: CYP3A4 |
| D11886 |
Daridorexant (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11954 |
Belzutifan (JAN/USAN/INN); Welireg (TN) |
(P) Enzyme: CYP2C19 |
| D11968 |
Teneligliptin hydrobromide (JAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) unclassified |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12130 |
Drospirenone, ethinyl estradiol and levomefolate calcium; Beyaz (TN); Safyral (TN); Tydemy (TN) |
(P) Enzyme: CYP3A4 |
| D12265 |
Mavacamten (JAN/USAN/INN); Camzyos (TN) |
(P) Enzyme: CYP2C19 |
| D12269 |
Nirmatrelvir and ritonavir; Paxlovid (TN) |
(CI,P) Enzyme: CYP3A4 |
| D12301 |
Adagrasib (USAN/INN); Krazati (TN) |
(P) Enzyme: CYP3A4 |
| D12312 |
Codeine phosphate and chlorpheniramine maleate; Tuxarin (TN) |
(P) unclassified |
| D12313 |
Chlorpheniramine polistirex and codeine polistirex; Tuzistra (TN) |
(P) Enzyme: CYP3A4 |
| D12353 |
Ensitrelvir fumarate (USAN); Ensitrelvir fumaric acid (JAN); Xocova (TN) |
(P) unclassified |
| D12403 |
Venlafaxine besylate monohydrate; Venlafaxine besylate (TN) |
(P) unclassified |
| D12444 |
Nilotinib hydrochloride dihydrate (JAN) |
(P) Enzyme: CYP3A4 |
| D12483 |
Olutasidenib (USAN/INN); Rezlidhia (TN) |
(P) Enzyme: CYP3A4 |
| D12486 |
Finasteride and tadalafil; Entadfi (TN) |
(P) Enzyme: CYP3A4 |
| D12497 |
Drospirenone and estradiol; Angeliq (TN) |
(P) Enzyme: CYP3A4 |
| D12544 |
Vortioxetine hemihydrobromide (USAN) |
(P) Enzyme: CYP2C19 |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) unclassified |
| D12609 |
Dasatinib laurylsulfate (USAN) |
(P) Enzyme: CYP3A4 |
| D12619 |
Ensitrelvir (USAN/INN) |
(P) unclassified |
| D12637 |
Darunavir hydrate |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D12660 |
Alphacetylmethadol (INN) |
(P) unclassified |
| D12661 |
Betacetylmethadol (INN) |
(P) unclassified |
| D12662 |
Allylprodine (INN) |
(P) unclassified |
| D12663 |
Ethylmethylthiambutene (INN) |
(P) unclassified |
| D12664 |
Diethylthiambutene (INN) |
(P) unclassified |
| D12665 |
Dimethylthiambutene (INN) |
(P) unclassified |
| D12666 |
Alphameprodine (INN); alpha-Meprodine |
(P) unclassified |
| D12667 |
Betameprodine (INN); beta-Meprodine |
(P) unclassified |
| D12668 |
Clonitazene (INN) |
(P) unclassified |
| D12669 |
Etonitazene (INN) |
(P) unclassified |
| D12670 |
Desomorphine (INN) |
(P) unclassified |
| D12671 |
Dipipanone (BAN) |
(P) unclassified |
| D12672 |
Dimenoxadol (INN) |
(P) unclassified |
| D12673 |
Dimepheptanol (INN) |
(P) unclassified |
| D12674 |
Alphamethadol (INN) |
(P) unclassified |
| D12675 |
Betamethadol (INN) |
(P) unclassified |
| D12676 |
Isomethadone (INN) |
(P) unclassified |
| D12677 |
Proheptazine (INN) |
(P) unclassified |
| D12678 |
Alphaprodine (INN) |
(P) unclassified |
| D12679 |
Betaprodine (INN) |
(P) unclassified |
| D12680 |
Etoxeridine (INN) |
(P) unclassified |
| D12681 |
Hydroxypethidine (INN); Bemidone |
(P) unclassified |
| D12682 |
Furethidine (INN) |
(P) unclassified |
| D12683 |
Piminodine (INN) |
(P) unclassified |
| D12685 |
Benzethidine (INN) |
(P) unclassified |
| D12686 |
Hydromorphinol (INN) |
(P) unclassified |
| D12687 |
Levophenacylmorphan (INN) |
(P) unclassified |
| D12688 |
Phenomorphan (INN) |
(P) unclassified |
| D12689 |
Methyldihydromorphine (INN) |
(P) unclassified |
| D12690 |
Metopon (BAN); Methyldihydromorphinone |
(P) unclassified |
| D12691 |
Methyldesorphine (INN) |
(P) unclassified |
| D12692 |
Norlevorphanol (INN) |
(P) unclassified |
| D12693 |
Phenampromide (INN) |
(P) unclassified |
| D12694 |
Diampromide (INN) |
(P) unclassified |
| D12695 |
Levomoramide (INN) |
(P) unclassified |
| D12696 |
Levomethorphan (INN) |
(P) unclassified |
| D12697 |
Morpheridin (INN) |
(P) unclassified |
| D12698 |
Phenadoxone (INN) |
(P) unclassified |
| D12699 |
Dioxaphetyl butyrate (INN) |
(P) unclassified |
| D12700 |
Acetorphine (INN) |
(P) unclassified |
| D12701 |
Norpipanone (INN) |
(P) unclassified |
| D12752 |
Darunavir propylene glycolate |
(CI,P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D12756 |
Vonoprazan and amoxicillin; Voquezna (TN) |
(P) Enzyme: CYP2C19 CYP3A4 |
| D12816 |
Dexlansoprazole sesquihydrate |
(P) Enzyme: CYP2C19 CYP3A4 / CYP inhibition: CYP2C19 |
| D12854 |
Nilotinib laurylsulfate (USAN) |
(P) Enzyme: CYP3A4 |
